Genomics

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Researchers uncover new 'hidden' gene in SARS-CoV-2

Researchers have discovered a new "hidden" gene in SARS-CoV-2--the virus that causes COVID-19--that may have contributed to its unique biology and pandemic potential.

10 Nov 2020

SARS-CoV-2 RNA genome structure reveals potential targets for development of drugs

The SARS-CoV-2 coronavirus RNA genome structure was studied in detail by researchers from the University of Groningen, the International Institute of Molecular and Cell Biology in Warsaw, and Leiden University.

10 Nov 2020

Consumption of tree nuts impacts sperm DNA methylation

Many environmental and lifestyle factors have been implicated in the decline of sperm quality, with diet being one of the most plausible factors identified in recent years.

9 Nov 2020

Genomic surveillance of yellow fever outbreak in São Paulo

Yellow fever virus is normally confined to the Amazon region, but the virus circulated in the Southeast of Brazil between 2016 and 2018, causing the worst epidemic and epizootic outbreaks there for decades.

5 Nov 2020

Argonne supports the largest analysis of COVID-19 genome sequences in the U.S.

Argonne computational resources supported the largest comprehensive analysis of COVID-19 genome sequences in the U.S. and helped corroborate growing evidence of a protein mutation.

5 Nov 2020

New, effective CRISPR-based gene drive approach to control transmission of malaria parasites

Employing a strategy known as "population modification," which involves using a CRISPR-Cas9 gene drive system to introduce genes preventing parasite transmission into mosquito chromosomes, University of California researchers have made a major advance in the use of genetic technologies to control the transmission of malaria parasites.

3 Nov 2020

UConn researcher identifies genes and regulatory elements critical to heart development

The advent of genome science has given researchers an unprecedented ability to understand the root causes of a host of conditions.

3 Nov 2020

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Breast cancer is the leading cause of cancer-related death among the female population globally, despite the ever-growing technology of early detection.

From Bruker BioSpin - NMR, EPR and Imaging 30 Oct 2020

Toxin-carrying virus implicated in the emergence of new Salmonella strain in pigs

Researchers at the Quadram Institute have implicated a toxin-carrying virus in the emergence of a new strain of Salmonella in pigs.

29 Oct 2020

Tumor suppressor gene represses 'jumping genes'

About half of all tumors have mutations of the gene p53, normally responsible for warding off cancer. Now, UT Southwestern scientists have discovered a new role for p53 in its fight against tumors: preventing retrotransposons, or "jumping genes," from hopping around the human genome.

29 Oct 2020

Severe ulcerative colitis linked to a newly-discovered strain of oral bacteria

Bacteria from the mouth could hold clues to understanding – and potentially treating – severe ulcerative colitis, a painful bowel disease.

29 Oct 2020

Study reveals complex and vast diversity of African genetic variation

The study, in which six Wits researchers were involved, show that these newly discovered variants were found mostly among newly sampled ethnolinguistic groups.

29 Oct 2020

Penn researchers awarded $5.4 million to find genetic risk markers for testicular cancer

The international hunt to find more genetic risk markers for testicular cancer is expanding. A team of researchers led by Katherine L. Nathanson, MD, deputy director of the Abramson Cancer Center and the Pearl Basser Professor for BRCA-Related Research in the Perelman School of Medicine at the University of Pennsylvania, was recently awarded $5.4 million over five years from the National Institutes of Health to continue the long-standing genomics work of the TEsticular CAncer Consortium (TECAC).

28 Oct 2020

Genetic analysis with RNA sequencing can increase diagnostic yield, shows study

In the world of rare genetic diseases, exome and genome sequencing are two powerful tools used to make a diagnosis. A recent addition to the toolkit, RNA sequencing, has been demonstrated to help researchers narrow down disease candidate variants identified first on exome and genome sequencing.

28 Oct 2020

Cleveland Clinic-led study identifies features associated with pathogenic and benign variants

An international team of researchers led by Cleveland Clinic's Lerner Research Institute has performed for the first time a wide-scale characterization of missense variants from 1,330 disease-associated genes.

27 Oct 2020

UVA research sheds light on how cancer remodels our chromosomes

Cancer remodels the architecture of our chromosomes so the disease can take hold and spread, researchers at the University of Virginia have revealed.

27 Oct 2020

Study finds new transposon-derived genes related to autism

The lack of some genes in the BEC/TCEAL cluster could be related to some alterations associated with the autism spectrum disorder, according to a preclinical study published in the journal Genome Biology, and led by Professor Jordi Garcia Fernàndez, from the Faculty of Biology and the Institute of Biomedicine of the University of Barcelona, and researcher Jaime Carvajal, from the Andalusian Centre for Developmental Biology - University Pablo de Olavide.

27 Oct 2020

Genome-wide screens reveal new helpful and harmful COVID-19 related genes

Researchers at Yale University and the Broad Institute of MIT and Harvard screened hundreds of millions of cells exposed to the COVID-19 and MERS viruses and identified dozens of genes that both enable the viruses to replicate in cells and also those that seem to slam the door on the virus.

27 Oct 2020

Oral bacteria persist on wasted chewing gums for weeks

Researchers from the Institute of Integrative Systems Biology (I2SysBio), a joint center of the University of Valencia and the CSIC, have analyzed the bacteria from used chewing gums from five different countries.

23 Oct 2020

Study reveals unexpected eating habits of fringe-lipped bats

Poop is full of secrets. For scientists, digging into feces provides insights into animal diets and is particularly useful for understanding nocturnal or rare species. When animals eat, prey DNA travels all the way through animal digestive tracts and comes out again.

23 Oct 2020

Genomics

Researchers uncover new 'hidden' gene in SARS-CoV-2

SARS-CoV-2 RNA genome structure reveals potential targets for development of drugs

Consumption of tree nuts impacts sperm DNA methylation

Genomic surveillance of yellow fever outbreak in São Paulo

Argonne supports the largest analysis of COVID-19 genome sequences in the U.S.

New, effective CRISPR-based gene drive approach to control transmission of malaria parasites

UConn researcher identifies genes and regulatory elements critical to heart development

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Toxin-carrying virus implicated in the emergence of new Salmonella strain in pigs

Tumor suppressor gene represses 'jumping genes'

Severe ulcerative colitis linked to a newly-discovered strain of oral bacteria

Study reveals complex and vast diversity of African genetic variation

Penn researchers awarded $5.4 million to find genetic risk markers for testicular cancer

Genetic analysis with RNA sequencing can increase diagnostic yield, shows study

Cleveland Clinic-led study identifies features associated with pathogenic and benign variants

UVA research sheds light on how cancer remodels our chromosomes

Study finds new transposon-derived genes related to autism

Genome-wide screens reveal new helpful and harmful COVID-19 related genes

Oral bacteria persist on wasted chewing gums for weeks

Study reveals unexpected eating habits of fringe-lipped bats

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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