Genomics

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Spatial configuration of the genome is not inherited, but set up during embryogenesis

The architecture of the DNA-protein complexes that make up the genome in each cell nucleus regulates the course of early embryonic development.

23 May 2019

Scientists uncover unique set of genes that play a role in muscle cellular gene regulation

York University scientists have uncovered a unique set of genes that play a role in muscle cellular gene expression and differentiation which could lead to new therapeutic targets to prevent the spread of muscle cancer.

23 May 2019

Large study links rare DNA alterations to type 2 diabetes

An international consortium of scientists has analyzed protein-coding genes from nearly 46,000 people, linking rare DNA alterations to type 2 diabetes.

23 May 2019

Genetic switch that controls conversion of bad to good fat identified

Fat cells. They are the bane of a dieter's existence, but fat is important. Previous studies showed the subcutaneous white fat cells can transform to brown and beige varieties when exposed to cold stress.

23 May 2019

Scientists develop new genetic tool to modify and understand gene function

Scientists of the National Center for Cardiovascular Research led by Rui Benedito have developed a new genetic tool (iSuRe-Cre) that provides certainty in Cre-inducible genetic modifications, a key technique for understanding gene function.

22 May 2019

Yeast species thrives, despite losing DNA repair genes years ago

Researchers have discovered an ancient species of budding yeast that has lost dozens of DNA repair genes, without any adverse effects.

22 May 2019

Newly discovered molecules safely halt the gene editing process

Scientists have discovered two non-toxic molecules that safely halt the CRISPR-Cas9 gene editing process.

22 May 2019

Scientists create bacteria with man-made DNA

In a landmark research study, a living organism (E. coli) has been made using entirely human-made DNA.

21 May 2019

Archaeological evidence shows anatomically modern humans were roasting and eating plant starches

New discoveries made at the Klasies River Cave in South Africa's southern Cape, where charred food remains from hearths were found, provide the first archaeological evidence that anatomically modern humans were roasting and eating plant starches, such as those from tubers and rhizomes, as early as 120,000 years ago.

20 May 2019

Insulin-producing beta cells can change their function in diabetes, reveals study

A revolutionary new study using only materials derived from humans has revealed that insulin-producing beta cells can change their function in diabetes - and that this change may be reversible.

17 May 2019

CRISPR uncovers which gene fusions are critical for growth of cancer cells

In the first large-scale analysis of cancer gene fusions, which result from the merging of two previously separate genes, researchers at the Wellcome Sanger Institute, EMBL-EBI, Open Targets, GSK and their collaborators have used CRISPR to uncover which gene fusions are critical for the growth of cancer cells.

16 May 2019

Researchers use cutting-edge technology to read the dark heart of chromosomes

Although the genomes of thousands of plant and animal species have been sequenced, for most of these genomes a significant portion is missing — the highly repetitive DNA.

15 May 2019

Physician training makes doctors' DNA to age six times faster than normal

In just a few short weeks, tens of thousands of newly minted doctors will start the most intense year of their training: the first year of residency, also called the intern year.

15 May 2019

Research on repetitive worm behavior may shed light on repetition in humans

Repetition can be useful if you're trying to memorize a poem, master a guitar riff, or just cultivate good habits.

13 May 2019

Researchers reveal ebb and flow of gene expression that may awaken neural stem cells

The human body has powerful healing abilities. But treating brain disorders is no easy task, as brain cells -- neurons -- have limited ability to regenerate.

13 May 2019

'Eye-in-a-dish' model reveals genetic variants that may contribute to AMD

Age-related macular degeneration is one of the most common causes of vision loss in people over age 65.

10 May 2019

Insights into parasitic yeast species could lead to new strategies for controlling yeast pathogens

Insights into the genes and proteins involved in the predatory behavior of a parasitic yeast species could lead to new strategies for controlling yeast pathogens, according to a study published May 9 in the open-access journal PLOS Pathogens by Jürgen Wendland of the Carlsberg Research Laboratory in Denmark and Vrije Universiteit Brussel in Belgium, and colleagues.

10 May 2019

Egg yolk precursor protein plays key role in regulating mosquitos’ attraction to humans

Feeding mosquitoes sugar makes them less attracted to humans, a response that is regulated by the protein vitellogenin, according to a study publishing May 9 in the open-access journal PLOS Biology by Jessica Dittmer, Paolo Gabrieli and colleagues at the Università degli Studi di Pavia in Italy.

10 May 2019

IDT announces significant NGS portfolio expansion

Demonstrating its advocacy for genomics research, Integrated DNA Technologies announces a significant expansion to its NGS portfolio.

From Integrated DNA Technologies 10 May 2019

New computational framework reveals impact of arthritis drugs on gene expression

A new computational framework has revealed key differences between four rheumatoid arthritis medications and their impact on biological pathways in mice.

10 May 2019

Genomics

Spatial configuration of the genome is not inherited, but set up during embryogenesis

Scientists uncover unique set of genes that play a role in muscle cellular gene regulation

Large study links rare DNA alterations to type 2 diabetes

Genetic switch that controls conversion of bad to good fat identified

Scientists develop new genetic tool to modify and understand gene function

Yeast species thrives, despite losing DNA repair genes years ago

Newly discovered molecules safely halt the gene editing process

Scientists create bacteria with man-made DNA

Archaeological evidence shows anatomically modern humans were roasting and eating plant starches

Insulin-producing beta cells can change their function in diabetes, reveals study

CRISPR uncovers which gene fusions are critical for growth of cancer cells

Researchers use cutting-edge technology to read the dark heart of chromosomes

Physician training makes doctors' DNA to age six times faster than normal

Research on repetitive worm behavior may shed light on repetition in humans

Researchers reveal ebb and flow of gene expression that may awaken neural stem cells

'Eye-in-a-dish' model reveals genetic variants that may contribute to AMD

Insights into parasitic yeast species could lead to new strategies for controlling yeast pathogens

Egg yolk precursor protein plays key role in regulating mosquitos’ attraction to humans

IDT announces significant NGS portfolio expansion

New computational framework reveals impact of arthritis drugs on gene expression

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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