Genomics

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Scientists use 3D mapping techniques to unravel mystery of blood stem cells

Princess Margaret scientists have revealed how stem cells are able to generate new blood cells throughout our life by looking at vast, uncharted regions of our genetic material that hold important clues to subtle biological changes in these cells.

25 Nov 2020

Research sheds new light on how the CRISPR immune system evolved

With new insights into how the genetic tool CRISPR - which allows direct editing of our genes - evolved and adapted, we are now one step closer to understanding the basis of the constant struggle for survival that takes place in nature. The results can be used in future biotechnologies.

25 Nov 2020

Study: None of the SARS-CoV-2 mutations appear to increase transmissibility in humans

None of the mutations currently documented in the SARS-CoV-2 virus appear to increase its transmissibility in humans, according to a study led by UCL researchers.

25 Nov 2020

Study reveals a gene responsible for anthraquinone synthesis in plants

Anthraquinones are a class of naturally occurring compounds prized for their medicinal properties, as well as for other applications, including ecologically friendly dyes.

25 Nov 2020

Mother's protein found to be involved in genomic imprinting process

Mothers leave their mark on their children in many ways - and Australian researchers have discovered a protein called SMCHD1 is involved in this 'imprinting' process.

24 Nov 2020

New findings could pave the way for more effective, safer and cheaper gene therapy

In a promising advance for affordable, personalized medicine, researchers have used metal-organic frameworks to successfully deliver the genetic snipping tool CRISPR/Cas9 into human cancer cells.

20 Nov 2020

Specific bacterial sRNA plays key role in symbiosis between Vibrio fischeri and squid

Bacteria living symbiotically within the Hawaiian bobtail squid can direct the host squid to change its normal gene-expression program to make a more inviting home, according to a new study published in PLoS Biology by researchers at the University of Hawai'i (UH) at Mānoa School of Ocean and Earth Science and Technology (SOEST).

20 Nov 2020

Researchers identify CLCN6 as disease gene for severe lysosomal neurodegenerative disorder

A mutation in the CLCN6 gene is associated with a novel, particularly severe neurodegenerative disorder. Scientists from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie and the Max Delbrück Center für Molekulare Medizin, together with an international team of researchers, have now analyzed the effect of a point mutation that was found in three unrelated affected children.

19 Nov 2020

Research shows sexual lineage plays crucial role in transgenerational plasticity

A new pair of papers published in the Journal of Animal Ecology has shown that sexual lineage matters for how offspring receive adaptations from parents in stickleback fish.

18 Nov 2020

Researchers use proteogenomics to better understand the biological complexity of breast cancer

Researchers at Baylor College of Medicine, the Broad Institute of MIT and Harvard and other institutions have applied powerful proteogenomics approaches to better understand the biological complexity of breast cancer.

18 Nov 2020

Finding ways to mitigate food allergies at the source

Food allergies are a big problem. About 7% of children and 2% of adults in the U.S. suffer from some kind of food allergy.

18 Nov 2020

Somatic mutation may act as a natural gene therapy in patients with rare autosomal disease

Researchers affiliated with the Center for Cell-Based Therapy in Ribeirão Preto, Brazil, have identified for the first time a non-hereditary mutation in blood cells from a patient with GATA2 deficiency, a rare autosomal disease caused by inherited mutations in the gene that encodes GATA-binding protein 2 (GATA2).

17 Nov 2020

Scientists reveal how genetically modified organisms can help mitigate climate change

Fighting the imminent climate change crisis has now become a global priority. In this regard, scientists in the US have discussed how gene editing technology can modify plants and organisms to reduce atmospheric CO2 and slow down climate change.

17 Nov 2020

Sanger Institute and COG-UK get £12.2M funding to build genomic surveillance system for COVID-19

The Department for Health and Social Care Testing Innovation Fund has backed the Wellcome Sanger Institute and the COVID-19 Genomics UK Consortium in expanding whole genome sequencing of positive SARS-CoV-2 virus samples to map how COVID-19 spreads and evolves.

16 Nov 2020

Study reveals a previously undetected repertoire of cancer driver genes

A new study, led by researchers from the University of California, Irvine, has deepened the understanding of epigenetic mechanisms in tumorigenesis and revealed a previously undetected repertoire of cancer driver genes.

12 Nov 2020

TMDU and Fujitsu complete cancer gene network analysis in less than a day

Tokyo Medical and Dental University and Fujitsu Laboratories Limited have recently completed, in less than a day, estimation of the network that represents the influence relationship between genes and prediction of their relationship with infiltration and metastasis based on genes highly likely to be involved in cancer development.

12 Nov 2020

Comparison of 240 mammal genomes helps geneticists to identify disease mutations

A large international consortium led by scientists at Uppsala University and the Broad Institute of MIT and Harvard has sequenced the genome of 130 mammals and analyzed the data together with 110 existing genomes to allow scientist to identify which are the important positions in the DNA.

11 Nov 2020

Genomics

Scientists use 3D mapping techniques to unravel mystery of blood stem cells

Research sheds new light on how the CRISPR immune system evolved

Study: None of the SARS-CoV-2 mutations appear to increase transmissibility in humans

Study reveals a gene responsible for anthraquinone synthesis in plants

Mother's protein found to be involved in genomic imprinting process

New findings could pave the way for more effective, safer and cheaper gene therapy

Specific bacterial sRNA plays key role in symbiosis between Vibrio fischeri and squid

Researchers identify CLCN6 as disease gene for severe lysosomal neurodegenerative disorder

Research shows sexual lineage plays crucial role in transgenerational plasticity

Researchers use proteogenomics to better understand the biological complexity of breast cancer

Finding ways to mitigate food allergies at the source

Somatic mutation may act as a natural gene therapy in patients with rare autosomal disease

Scientists reveal how genetically modified organisms can help mitigate climate change

Sanger Institute and COG-UK get £12.2M funding to build genomic surveillance system for COVID-19

Study reveals a previously undetected repertoire of cancer driver genes

TMDU and Fujitsu complete cancer gene network analysis in less than a day

Comparison of 240 mammal genomes helps geneticists to identify disease mutations

Researchers uncover potential genetic target for treating endometriosis

Uracil point mutations found in SARS-CoV-2 variants alter innate immune responses

Two paralogous androgen receptor genes control social dominance

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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