Genomics

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New tool judges accuracy of computer predictions of tumor’s genetic diversity

Cancers are often made up of many cells which vary genetically to each other. These genetic differences mean the cancer may be particularly susceptible or resistant to a given treatment. As a result, identifying these variations can help clinicians decide which treatment is most likely to be successful for a specific patient.

10 Jan 2020

First-ever genomic analysis of puberty yields insights into critical areas of human health

In the first-ever genome-scale analysis of the puberty process in humans, researchers at Huntsman Cancer Institute at the University of Utah outline distinct and critical changes to stem cells in males during adolescence.

9 Jan 2020

Common genetic defect in prostate cancer associated with worse prognosis

Like security screening to make sure nothing harmful makes its way into a crowded area, cells in the human body use checkpoints to control their growth and prevent harmful mutations from making their way into new cell populations and causing trouble.

9 Jan 2020

Researchers identify synergistic cellular pathways that considerably amplify lifespan

Scientists at the MDI Biological Laboratory, in collaboration with scientists from the Buck Institute for Research on Aging in Novato, Calif., and Nanjing University in China, have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research.

9 Jan 2020

ERS Genomics and New England Biolabs sign agreement to commercialize CRISPR/Cas9 tools, reagents

ERS Genomics Limited, which was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property co-owned by Dr. Emmanuelle Charpentier, today announced it has signed an agreement with New England Biolabs, a global leader in the discovery and production of enzymes for molecular biology applications, granting NEB rights to sell CRISPR/Cas9 tools and reagents.

From New England Biolabs 9 Jan 2020

New ACMG Points to Consider document on use of fetal exome sequencing in prenatal care

A new Points to Consider document from the ACMG aims to assist referring physicians, laboratory geneticists, genetic counselors and other medical professionals in understanding the complexity and implications of exome sequencing in prenatal care.

8 Jan 2020

Palmetto GBA now covers Genomic Testing Cooperative’s solid tumor molecular profile

Genomic Testing Cooperative, LCA announced that the Medicare Administrative Contractor Palmetto GBA (MolDx) has established coverage for its solid tumor molecular profile.

7 Jan 2020

Hobbyist DNA services may be vulnerable to genetic hacking

Online services that allow users to upload their genetic information, research genealogy and find lost relatives may be vulnerable to a sort of genetic hacking, according to two geneticists at the University of California, Davis. A paper describing the work is published Jan. 7 in the journal eLife.

7 Jan 2020

Major genetic study provides most comprehensive map of breast cancer risk variants to date

A major international study of the genetics of breast cancer has identified more than 350 DNA 'errors' that increase an individual's risk of developing the disease. The scientists involved say these errors may influence as many as 190 genes.

7 Jan 2020

Researchers discover a way to restore strength of cardiac muscles in aging fruit flies

Researchers may have discovered a way to turn back the clock on aging heart muscles in fruit flies, a development that could lead to new therapies for older humans with heart disease.

7 Jan 2020

The first clinical trials of CRISPR gene editing have shown promising results

Results of clinical trials testing CRISPR suggest that treating diseases with the gene-editing tool may be on the horizon.

7 Jan 2020

Some genetic sequencing misses out large parts of the genome

A study of patient samples has found that more than a quarter of genes are missed in genetic sequencing procedures.

7 Jan 2020

Using CRISPR to switch off pain gene becomes a possibility with new study

A pathbreaking study reports success in disabling an important gene that is responsible for inducing the sensation of pain.

7 Jan 2020

Study uncovers genes controlling mycorrhizal colonization in soybean

Like most plants, soybeans pair up with soil fungi in a symbiotic mycorrhizal relationship. In exchange for a bit of sugar, the fungus acts as an extension of the root system to pull in more phosphorus, nitrogen, micronutrients, and water than the plant could on its own.

6 Jan 2020

Whole exome sequencing routinely fails to adequately analyze large segments of DNA

Children who undergo expansive genetic sequencing may not be getting the thorough DNA analysis their parents were expecting, say experts at UT Southwestern Medical Center.

6 Jan 2020

Prison sentences given to scientists who gene-edited babies

The three scientists responsible for the creation of three gene-edited babies have received prison sentences.

6 Jan 2020

Competition between groups has negative effects on wild chimpanzees' reproductive success

Both species, humans and chimpanzees, can be extremely territorial, and territorial disputes between groups can turn violent, with individuals killing each other. In humans, such between-group competition can escalate to war and devastating loss of human life.

3 Jan 2020

Promega and MilliporeSigma sign license agreement to expand the potential of CRISPR

Promega announce license agreement with MilliporeSigma, a leader in genome editing, to access MilliporeSigma’s foundational CRISPR genome-editing technology.

From Promega Corporation 2 Jan 2020

Common plasticizer leads to fertility problems in roundworms

A new study published 9th January in PLOS Genetics by Mónica Colaiácovo of Harvard Medical School and colleagues reports that the most commonly used plasticizer, diethylhexyl phthalate, leads to fertility problems by causing an excess number of breaks in the DNA during egg production, and then interfering with the repair systems that fixes the breaks.

2 Jan 2020

Advancement in reconstitution of the blood system from human pluripotent stem cells

The reconstitution of the blood system in humans holds great therapeutic potential to treat many disorders, like blood cancers, sickle-cell anemia and others.

31 Dec 2019

Genomics

New tool judges accuracy of computer predictions of tumor’s genetic diversity

First-ever genomic analysis of puberty yields insights into critical areas of human health

Common genetic defect in prostate cancer associated with worse prognosis

Researchers identify synergistic cellular pathways that considerably amplify lifespan

ERS Genomics and New England Biolabs sign agreement to commercialize CRISPR/Cas9 tools, reagents

New ACMG Points to Consider document on use of fetal exome sequencing in prenatal care

Palmetto GBA now covers Genomic Testing Cooperative’s solid tumor molecular profile

Hobbyist DNA services may be vulnerable to genetic hacking

Major genetic study provides most comprehensive map of breast cancer risk variants to date

Researchers discover a way to restore strength of cardiac muscles in aging fruit flies

The first clinical trials of CRISPR gene editing have shown promising results

Some genetic sequencing misses out large parts of the genome

Using CRISPR to switch off pain gene becomes a possibility with new study

Study uncovers genes controlling mycorrhizal colonization in soybean

Whole exome sequencing routinely fails to adequately analyze large segments of DNA

Prison sentences given to scientists who gene-edited babies

Competition between groups has negative effects on wild chimpanzees' reproductive success

Promega and MilliporeSigma sign license agreement to expand the potential of CRISPR

Common plasticizer leads to fertility problems in roundworms

Advancement in reconstitution of the blood system from human pluripotent stem cells

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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