Genomics

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Aging may have originated at the very beginning of life, says study

A new USC Dornsife study indicates that aging may have originated at the very beginning of the evolution of life, at the same time as the evolution of the first genes.

13 Sep 2018

Study provides complete picture of HPV virus-head and neck cancer connections

Human papillomavirus is widely known to cause nearly all cases of cervical cancer. However, you might not know that HPV also causes 70 percent of oropharyngeal cancer, a subset of head and neck cancers that affect the mouth, tongue, and tonsils.

12 Sep 2018

Study finds overlapping copy number variations in Japanese patients with autism and schizophrenia

Common genetic variants may underlie autism spectrum disorder and schizophrenia across human populations, according to a study appearing September 11th in the journal Cell Reports.

12 Sep 2018

Differences in mitochondrial DNA determine severity of heart disease caused by nDNA mutation

Differences in the DNA within the mitochondria, the energy-producing structures within cells, can determine the severity and progression of heart disease caused by a nuclear DNA mutation.

12 Sep 2018

Penn receives NIH grant to create Center for Sub-Cellular Genomics

The five-year, $10.5 million grant from the NIH is the first CEGS awarded to Penn and funds the creation of the Center for Sub-Cellular Genomics.

12 Sep 2018

Scientists develop first DNA-based test for predicting risk of leukemia relapse

A group of Canadian and Korean scientists and physicians have developed the first DNA-based test that allows them to tell which patients will relapse after receiving chemotherapy and a bone marrow transplant, for their acute myeloid leukemia, or AML.

11 Sep 2018

New framework combines three existing methods to find cancer cell mutations

Cancer cells often have mutations in their DNA that can give scientists clues about how the cancer started or which treatment may be most effective. Finding these mutations can be difficult, but a new method may offer more complete, comprehensive results.

10 Sep 2018

Discovery provides new hope for anti-HIV vaccine

Researchers have discovered that the RNA genome of the HIV virus can influence the immune response generated, and thus influence human survival.

10 Sep 2018

Researchers develop the first interactive model of cell division

Researchers have developed an interactive atlas of human cell division, that shows the effect of protein misfolding on mitosis.

10 Sep 2018

Acute changes in extracellular matrix can trigger rapid change in cell’s metabolism

UCLA researchers have found that the extracellular matrix, the dense network of proteins and carbohydrates that surround a cell, can influence how cells move within the body by regulating their sugar consumption.

10 Sep 2018

Family genetic background essential for understanding autism progression

Whether an individual develops a neurodevelopmental disorder like autism or ADHD and the severity of that disorder depends on genetic changes beyond a single supposedly disease-causing mutation.

7 Sep 2018

Chemical signals influence guest-host protocell interactions

Resident artificial cells shown to leave their protocell hosts when triggered by a chemical signal that causes them to behave antagonistically.

7 Sep 2018

UTA doctoral student receives prestigious grant to fund research in genetic variation

A doctoral student in biology at The University of Texas at Arlington has received a prestigious grant to fund her research in genetic variation in whiptail lizards.

7 Sep 2018

Researchers find new gene in brown fat cells that may help in treatment of obesity

A team of researchers, led by Professor Jan-Wilhelm Kornfeld from the Department of Biochemistry and Molecular Biology, University of Southern Denmark, Elena Schmidt from the Max Planck Institute for Metabolism Research, Cologne, Germany and Martin Bilban from the Medical University, Vienna, Austria, have made a groundbreaking discovery in obesity research.

7 Sep 2018

Researchers hope to translate mRNA drugs from lab to medicine cabinet

In cells, ribosomes translate messenger RNA into proteins. And in the nascent field of mRNA therapeutics, researchers and investors are hoping to translate mRNA drugs from the lab to the medicine cabinet.

6 Sep 2018

Researchers find bacterial DNA in intestine of newborn calves

Researchers at the University of Helsinki, Finland have found bacterial DNA in the intestine of newborn calves, representing quite a diverse variety of bacterial species.

6 Sep 2018

Link discovered between tumor genome changes and mortality risk across cancer types

Researchers have discovered a link between certain changes in the genome of a tumor and increased chances of death across multiple types of cancer.

5 Sep 2018

New method identifies 25 genetic changes associated with longer human lifespan

A new method has made it possible to identify twenty-five parallel mutations located in genes associated with wound healing, blood coagulation and cardiovascular disorders. The results could help to develop new drugs to treat aging-related diseases.

5 Sep 2018

Research reveals noise-canceling mechanisms in developmental biology

Noise is usually considered a nuisance, for example when preventing us from clearly hearing what someone is saying. The general concept of noise applies more broadly. In biology, the physical differences between organisms of the same type, for example two humans, originate from so-called developmental noise -- ultimately stemming from probabilistic collisions between reacting molecules and environmental conditions in cells during the early stages of the organism's growth.

4 Sep 2018