Genomics

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Researchers identify chemical compounds that increase stability of haploid cell

Since the emergence of molecular genetics more than fifty years ago, scientists have tried to isolate haploid mammalian cells, that is, cells with half the number of chromosomes contained in somatic cells. Haploid cells are a powerful genetic tool to analyze gene function.

17 Jul 2019

Study identifies genomic differences that impact response to Cryptococcus infection

Cryptococcus neoformans is a fungal pathogen that infects people with weakened immune systems, particularly those with advanced HIV/AIDS. New University of Minnesota Medical Research could mean a better understanding of this infection and potentially better treatments for patients.

16 Jul 2019

New method spots rare immune cells reactive against cancer

Researchers from the Garvan Institute of Medical Research have developed a new method to spot rare immune cells that are reactive against cancer cells, from within a patient's own immune system.

16 Jul 2019

Inhibition of p38 protein boosts formation of blood vessels in colon cancer

A study performed at the Institute for Research in Biomedicine and published in the journal Nature Communications demonstrates that inhibition of the p38 protein boosts the formation of blood vessels in human and mice colon cancers.

16 Jul 2019

EMBL study reveals uncoupling between chromatin topology and gene expression

Molecular biologists long thought that domains in the genome’s 3D organization control how genes are expressed.

16 Jul 2019

New study identifies eight genetic variants associated with anorexia nervosa

A new large-scale genome-wide association study published in Nature Genetics, has identified eight genetic variants significantly associated with anorexia nervosa; and the research shows that the origins of this serious disorder appear to be both metabolic and psychiatric.

16 Jul 2019

Researchers use blood samples from zoo to improve computer-assisted disease prognosis

The researchers want to use similar genetic patterns, which have been present in the blood of humans and animals for thousands of years, to improve computer-assisted disease prognosis.

16 Jul 2019

Evaluating safety and efficacy of magnetically labeled mesenchymal stem cells

Cells equipped with superparamagnetic iron oxide nanoparticles can be directed to a specific location by an external magnetic field, which is beneficial for tissue repair.

16 Jul 2019

New review highlights opportunities and challenges in metagenomics

A new expert review highlights the opportunities and methodological challenges at this critical juncture in the growth of the field of metagenomics.

16 Jul 2019

Research reveals the parenting habits of our earliest extinct ancestors

Extended parental care is considered one of the hallmarks of human evolution. A stunning new research result published today in Nature reveals for the first time the parenting habits of one of our earliest extinct ancestors.

15 Jul 2019

Scientists discover hundreds of protein-pairs through coevolution study

Scientists have discovered hundreds of new protein-protein interactions by looking for co-evolution in some residues of aligned protein sequences.

15 Jul 2019

LexaGene’s beta prototype achieves 98.2% consistency with reference lab data

LexaGene Holdings, Inc., a biotechnology company that develops genetic analyzers for rapid pathogen detection and other molecular markers, announced today the test results from its first beta prototype placed at the Massachusetts Veterinary Referral Hospital in Woburn, MA. Mass Vet is one of 24 hospitals owned and operated by Ethos Veterinary Health.

15 Jul 2019

Mammalian mothers more likely to commit infanticide

In previous studies, males have been found to kill when females will not mate with them if they are still caring for an offspring sired by their previous partner. Dieter Lukas and Elise Huchard have now looked into infanticide by female mammals.

15 Jul 2019

Researchers discover gene linked to healthy aging in worms

People with the same lifespan do not necessarily have the same quality of life. As we live longer, extending quality of life -- "healthspan" -- is gaining importance.

12 Jul 2019

Ancient epigenetic change deactivates some genes linked to cancer

An epigenetic change, a form of DNA control, that deactivates some genes linked to cancer late in human development has been conserved for more than 400 million years, new research led by the Garvan Institute of Medical Research suggests.

11 Jul 2019

Comprehensive cell atlas of the human liver

The liver is one of the largest and most versatile organs of the human body. It turns sugars, proteins, and fats from our food into substances useful for the body and releases them to the cells.

11 Jul 2019

Research reveals genetic cause of deadly digestive disease in children

Nearly 10 years ago, a group of Israeli clinical researchers emailed Lawrence Berkeley National Laboratory (Berkeley Lab) geneticist Len Pennacchio to ask for his team's help in solving the mystery of a rare inherited disease that caused extreme, and sometimes fatal, chronic diarrhea in children.

11 Jul 2019

UCR scientists decode genome of black-eyed peas

UC Riverside scientists have decoded the genome of black-eyed peas, offering hope for feeding Earth's expanding population, especially as the climate changes.

10 Jul 2019

Common virus exists in over one-third of the countries worldwide

We are all the same, yet we are all different. With the participation of researcher Josefa Antón, from the University of Alicante's Department of Physiology, Genetics and Microbiology, a new study has shown how a family of tiny viruses lives in the guts of humans around the world, yet changes depending on which country we are from.

10 Jul 2019