Genomics

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Modern humans interbred with multiple Denisovan populations, suggests study

The findings are based on a new study led by Murray Cox from Massey University in New Zealand and made possible by sampling efforts led by Herawati Sudoyo from the Eijkman Institute for Molecular Biology in Jakarta, Indonesia.

12 Apr 2019

Study describes vulnerability shared by large subset of cancer cell lines

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth.

12 Apr 2019

Rare gut condition is more predictable from individual's genetic makeup, study finds

Hirschsprung disease - a rare condition where the failure of gut nerves to develop before birth leads to impaired bowel contractions that prevent infants from passing stool - is more predictable from an individual's genetic makeup than previously envisioned.

11 Apr 2019

Bacteria share genes with one another, even across tissue boundaries

Bacteria in the human body are sharing genes with one another at a higher rate than is typically seen in nature, and some of those genes appear to be traveling - independent of their microbial hosts - from one part of the body to another, researchers report in the journal Scientific Reports.

11 Apr 2019

Scientists develop new approach to unravel toxic effects of multiple stressors

Genomic markers are the key in a new approach for assessing the toxic effects arising from exposure to multiple stressors.

11 Apr 2019

Hundreds of new anti-cancer drug targets identified using CRISPR

A team of scientists from the Wellcome Sanger Institute have identified the genes that are essential for the survival of thirty types of cancer cells.

11 Apr 2019

New strategy for editing and repairing genetic mutation associated with microduplications

Scientists at UMass Medical School have developed a strategy for editing and repairing a particular type of genetic mutation associated with microduplications using CRISPR/Cas9 and a seldom-used DNA repair pathway.

11 Apr 2019

Key gene involved in transmission of African sleeping sickness identified

Life scientists from UCLA and the University of Bern have identified a key gene in the transmission of African sleeping sickness -- a severe disease transmitted by the bite of infected tsetse flies, which are common in sub-Saharan Africa.

10 Apr 2019

Alcohol, Cannabis and Other Drugs: A Pharmacological Evaluation

Understanding the interactions between alcohol and cannabis can provide researchers, clinicians and other HCPs with important information on the severity of their side effects.

10 Apr 2019

New bioinformatics method helps scientists to understand differences in gene regulation in cells

A Belgian team of computational biologists led by Stein Aerts has developed a new bioinformatics method called cisTopic.

10 Apr 2019

Scientists develop new CRISPR-based 'allelic drive'

New CRISPR-based gene drives and broader active genetics technologies are revolutionizing the way scientists engineer the transfer of specific traits from one generation to another.

10 Apr 2019

High Throughput Nucleic Acid Purification Simplified

Labs demand purity and flexibility for high throughput nucleic acid purification, while needing to complete difficult downstream analysis, for example NGS.

From Promega Corporation 9 Apr 2019

Study compares library preparation and sequencing platforms for single-cell RNA-sequencing

Researchers from University of Southern Denmark, Wellcome Sanger Institute and BGI, today published a study in the journal Genome Biology comparing the library preparation and sequencing platforms for single-cell RNA-sequencing.

9 Apr 2019

Study finds no major epigenetic differences between space astronaut and his earthbound twin brother

In a landmark study, a group of U.S. scientists from Johns Hopkins, Stanford University and other institutions has found no long-lasting, major differences between the epigenomes of astronaut Scott Kelly, who spent a year in space aboard the International Space Station, and his twin brother, Mark, who remained on Earth.

9 Apr 2019

Study demonstrates viability of gene editing strategy for recessive dystrophic epidermolysis bullosa

A group of researchers from the Centro de Investigación Biomédica en Red de Enfermedades Raras, Universidad Carlos III de Madrid, the Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, and the Instituto de Investigación Sanitaria Fundación Jiménez Díaz have led a study which demonstrates the viability of a gene editing strategy for recessive dystrophic epidermolysis bullosa (also known as butterfly chilidren) with the tool CRISPR/Cas9 in preclinical models with this disease.

8 Apr 2019

A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

A protein complex that is involved in nearly every step in the regulatory control of gene expression in cells has now been shown also to play a key role in clearing potential traffic jams in the production of RNA.

5 Apr 2019

Researchers discover how specific mutation obstructs healthy blood cell maturation

In the veins, stem cells constantly mature and develop into different blood cells that are necessary for the body to work properly.

5 Apr 2019

NYU biologists develop methods to validate gene regulatory networks

A team of biologists and computer scientists has mapped out a network of interactions for how plant genes coordinate their response to nitrogen, a crucial nutrient and the main component of fertilizer.

5 Apr 2019

Study uncovers genetic causes of poor sleep

The international collaboration, led by the University of Exeter and published in Nature Communications, has found 47 links between our genetic code and the quality, quantity and timing of how we sleep. They include ten new genetic links with sleep duration and 26 with sleep quality.

5 Apr 2019

Inauguration of NIDD, the Neuroimmunology Drug Development Summit

NIDD is the industry’s first meeting dedicated to targeting neuroimmunological mechanisms in order to develop clinically efficacious therapeutics.

From Neuroimmunology Drug Development 5 Apr 2019

Genomics

Modern humans interbred with multiple Denisovan populations, suggests study

Study describes vulnerability shared by large subset of cancer cell lines

Rare gut condition is more predictable from individual's genetic makeup, study finds

Bacteria share genes with one another, even across tissue boundaries

Scientists develop new approach to unravel toxic effects of multiple stressors

Hundreds of new anti-cancer drug targets identified using CRISPR

New strategy for editing and repairing genetic mutation associated with microduplications

Key gene involved in transmission of African sleeping sickness identified

Alcohol, Cannabis and Other Drugs: A Pharmacological Evaluation

New bioinformatics method helps scientists to understand differences in gene regulation in cells

Scientists develop new CRISPR-based 'allelic drive'

High Throughput Nucleic Acid Purification Simplified

Study compares library preparation and sequencing platforms for single-cell RNA-sequencing

Study finds no major epigenetic differences between space astronaut and his earthbound twin brother

Study demonstrates viability of gene editing strategy for recessive dystrophic epidermolysis bullosa

A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

Researchers discover how specific mutation obstructs healthy blood cell maturation

NYU biologists develop methods to validate gene regulatory networks

Study uncovers genetic causes of poor sleep

Inauguration of NIDD, the Neuroimmunology Drug Development Summit

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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