Genomics

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Study provides new insights into genetic factors underlying facial beauty

Genes play a role in determining the beauty of a person’s face, but that role varies with the person’s sex, according to a new study by Qiongshi Lu and colleagues at the University of Wisconsin-Madison, published 4th April in PLOS Genetics.

5 Apr 2019

UMSOM's Institute for Genome Sciences receives $17.5 million grant for infectious disease research

The Institute for Genome Sciences at the University of Maryland School of Medicine was awarded $17.5 million from the National Institute of Allergy and Infectious Diseases to fund the IGS Genome Center for Infectious Diseases for another five years.

5 Apr 2019

Poverty can become embedded across wide swaths of the genome, study finds

A new Northwestern University study challenges prevailing understandings of genes as immutable features of biology that are fixed at conception.

4 Apr 2019

Study evaluates effects of unpaired 1 gene overexpression on lifespan in flies

Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS announce the publication of a scientific article titled "Effects of unpaired 1 gene overexpression on the lifespan of Drosophila melanogaster" in BMC Systems Biology - an open access journal publishing original peer-reviewed research articles in experimental and theoretical aspects of the function of biological systems at the molecular, cellular or organismal level.

4 Apr 2019

Mutation in Huntington’s disease may alter interactions of Huntingtin protein with Rac1

Since 1993, when the gene that causes Huntington's disease was identified, there has been intense focus on understanding how this genetic mutation causes the disease's severe progressive neural deterioration.

4 Apr 2019

Simplifying Gene Expression Analysis in Neuroscience Research

In this interview, Kevin Gamber introduces the Neuroscience panel of the NanoString service for gene expression analysis from Canopy Biosciences.

From Canopy Biosciences 3 Apr 2019

New Chromatrap ChIP-seq kit performs chromatin immunoprecipitation with unparalleled sensitivity

Porvair Sciences announces version 2.0 of its Chromatrap® ChIP-seq kit - developed to perform chromatin immunoprecipitation with unparalleled sensitivity.

From Chromatrap® - Porvair Sciences Ltd 3 Apr 2019

New analysis establishes global microbial signatures for colorectal cancer

Cancers have long been known to arise due to environmental exposures such as unhealthy diet or smoking. Lately, the microbes living in and on our body have entered the stage as key players: while stomach cancer can be caused by a single bacterial species, Helicobacter pylori, the role that gut microbes play in the development of colorectal cancer - the third most common cancer worldwide - is less clear.

2 Apr 2019

Study finds gene variant which causes hairlessness in dogs

Hairlessness in dogs can be the result of deliberate breeding or, in certain breeds, a defect. A recent study completed at the University of Helsinki describes a gene variant in the SGK3 gene, which causes hairlessness in Scottish Deerhounds.

2 Apr 2019

Researchers discover natural gene therapy for intractable skin disease

Pathogenic gene mutations causing a type of intractable skin disease can be eliminated from some parts of patients' skin as they age, according to Hokkaido University researchers and their collaborators in Japan. This represents a form of natural gene therapy.

1 Apr 2019

Research reveals genomic basis of acute erythroid leukemia

Acute erythroid leukemia is a high-risk cancer with a dismal prognosis, uncertain genetic basis and controversy surrounding the diagnosis. That is changing, thanks to research led by St. Jude Children's Research Hospital that appears today in the journal Nature Genetics.

30 Mar 2019

Novel EU-funded project in the field of genomics

The European Advanced infraStructure for Innovative Genomics (EASI-Genomics), a project funded under the European Union's research and innovation programme Horizon 2020, will provide researchers free-of-charge access to cutting-edge European genomics facilities.

30 Mar 2019

Study highlights need to diversify population-level genetic data for better disease prediction

Polygenic scores can predict a person's risk for conditions like coronary artery disease, breast cancer, and type 2 diabetes (T2D) with great accuracy, even in patients who lack common warning signs. This new genome analysis tool holds promise for physicians, who may be able to intervene earlier to help prevent common disease for at-risk individuals.

30 Mar 2019

Study finds two new genes in the developmental defects of canine enamel

In addition to humans, hereditary disorders of enamel development occur in dogs, greatly impacting their dental health and wellbeing. A recent study reveals canine enamel disorders similar to those found in humans, linking them with ENAM and ACP4, two genes previously described in humans.

29 Mar 2019

UTM researchers uncover 'master pacemaker' for biological clocks

What makes a biological clock tick? According to a new study from U of T Mississauga, the surprising answer lies with a gene typically associated with stem and cancer cells.

28 Mar 2019

Probing Submicron Protein Aggregation using Asymmetrical Flow Field-Flow Fractionation, AF4, and Light Scattering

The most recent developments by Wyatt in their instrumentation and software have made the full potential of FFF accessible to a wider user base. In this interview, Kim R. Williams and Christoph Johann talk to News-Medical and Life Sciences about the technologies and their research.

From Waters | Wyatt Technology 27 Mar 2019

Researchers uncover mechanism that initiates sexual organs maturation

Puberty is a period of extensive changes of body morphology and function. As much as we are familiar with these life-altering changes, relatively little is known about what sets the whole process in motion.

26 Mar 2019

New study questions value of genome-wide polygenic score

What's known as the genome-wide polygenic score, or GPS, combines information from many thousands of genetic markers, each with only a minimal effect, to produce an overall assessment of disease risk based on an individual's entire genetic background.

26 Mar 2019

Luxia Scientific partners with Life Genomics to commercialize microbiome-based tests in the Nordic countries

Luxia Scientific, a French biotech dedicated to improving wellbeing and health for all through the analysis and understanding of the microbiome, announced today that it has signed an exclusive distribution agreement with Life Genomics to commercialize « 1test1TM » in Nordic countries.

From Luxia Scientific 25 Mar 2019

Understanding genetic interactions holds key to new personalized therapies

When the Human Genome Project was completed, in 2003, it opened the door to a radical new idea of health - that of personalized medicine, in which disease risk and appropriate treatment would be gleaned from one's genetic makeup.

25 Mar 2019