Genomics

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Researchers identify genes responsible for safener efficacy in grain sorghum

Weeds often emerge at the same time as vulnerable crop seedlings and sneak between plants as crops grow. How do farmers kill them without harming the crops themselves?

22 Mar 2019

Fluctuating growth rate of bacteria helps it to develop resistance against antibiotic

If an antibiotic doesn't kill all the bacteria that infects a patient, the surviving bugs may be particularly adept at timing their resurgence.

22 Mar 2019

New computer program developed by TGen lights up cancer-causing genetic mutations

By conjuring the spell "Lumos!" wizards in the mythical world of Harry Potter could light up the tip of their magic wands and illuminate their surroundings. So, too, does LumosVar, a computer program developed by the Translational Genomics Research Institute, "light up" cancer-causing genetic Var-ients, or mutations, illuminating how physicians might best treat their patients.

21 Mar 2019

CRISPR/Cas libraries could revolutionize drug discovery

CRISPR/Cas enables the targeted deactivation of genes by cutting DNA at pre-determined sites. This is accomplished by providing the Cas enzyme with a genetic zip code.

20 Mar 2019

Gene editing and designer babies experiments face global moratorium

Powerful gene editing tools could soon face a global regulations on their use on human embryos, sperms or eggs.

20 Mar 2019

Researchers track effects of epigenetic marks carried by sperm chromosomes

As an organism grows and responds to its environment, genes in its cells are constantly turning on and off, with different patterns of gene expression in different cells. But can changes in gene expression be passed on from parents to their children and subsequent generations?

20 Mar 2019

Androgen receptor plays vital role in regulating multiple mitochondrial processes

Androgens, commonly known as male hormones, stimulate prostate cancer cells to grow. Thus, many of the drugs to target that cancer focus on stopping androgen biosynthesis or blocking the androgen receptor. This standard treatment is known as androgen deprivation therapy.

20 Mar 2019

Study illuminates how hot spots of genetic variation evolved in the human genome

What makes one person different from one another, and how did these differences evolve? A study by University at Buffalo biologists is illuminating one aspect of this complicated question. The research examines hot spots of genetic variation within the human genome, examining the sections of our DNA that are most likely to differ significantly from one person to another.

20 Mar 2019

Gene medication shows promise to treat spinal cord injuries

The two-gene medication has been proven to recover motor functions in rats. After several months of treatment, rodents were able to use previously paralyzed limbs. Researchers at Kazan Federal University are now seeking pre-clinical trial investment.

18 Mar 2019

World's oldest semen viable for artificial insemination

Semen stored since 1968 in a laboratory in Sydney has been defrosted and successfully used to impregnate 34 Merino ewes, with the resulting live birth rate as high sperm frozen for just 12 months.

18 Mar 2019

Promising gene therapy could restore vision in humans

It was surprisingly simple. University of California, Berkeley, scientists inserted a gene for a green-light receptor into the eyes of blind mice and, a month later, they were navigating around obstacles as easily as mice with no vision problems.

15 Mar 2019

Natural speed limit on DNA replication sets pace for life's first steps

Fruit flies make for stingy mothers, imparting only a portion of the genetic building blocks their offspring need to survive. The rest must be produced by the fertilized egg in its first few steps of growth.

15 Mar 2019

Study describes epigenetic loss that changes how cells obtain energy from cancer

It has been known for decades that cancer cells have an altered metabolism and it is seen in several biochemical pathways and in particular, in the way they get energy for their survival.

15 Mar 2019

An Insider’s Guide to the chemagic™ Prime™ Junior Instrument

Masoud Toloue from PerkinElmer provides an overview of the chemagic Prime Junior Instrument and gives his inside tips for scientists working with nucleic acids.

From Revvity 14 Mar 2019

Rice University bioscientists reveal danger of vitamin B12 deficiency

Using roundworms, one of Earth's simplest animals, Rice University bioscientists have found the first direct link between a diet with too little vitamin B12 and an increased risk of infection by two potentially deadly pathogens.

14 Mar 2019

New method for on-the-spot genome analysis

The ability to read the genome - all the DNA of an organism - has vast potential to understand human health and disease.

14 Mar 2019

Scientists introduce a simple, reliable method for universal isothermal DNA amplification

Whether revealing a perpetrator with DNA evidence, diagnosing a pathogen, classifying a paleontological discovery, or determining paternity, the duplication of nucleic acids (amplification) is indispensable.

13 Mar 2019

DNAnexus launches innovative clinico-genomic cohort browser to accelerate research and discovery

DNAnexus, Inc., the leader in biomedical informatics and data management, today announced the addition of an innovative browser for clinico-genomic cohorts to its DNAnexus Apollo™ Platform, allowing for easy at-scale navigation and exploration on combined genotypic and phenotypic data.

12 Mar 2019

Experts issue new guidelines for use of genetic testing in psychiatric care

An expert committee of psychiatrists and geneticists has issued revised guidelines for the use of genetic testing in psychiatric care.

12 Mar 2019

CAR-T cell therapy could be on the horizon for patients with lupus

Researchers have developed a novel CAR-T cell therapy that can reduce B cell numbers known to cause the inflammatory responses in lupus.

7 Mar 2019

Genomics

Researchers identify genes responsible for safener efficacy in grain sorghum

Fluctuating growth rate of bacteria helps it to develop resistance against antibiotic

New computer program developed by TGen lights up cancer-causing genetic mutations

CRISPR/Cas libraries could revolutionize drug discovery

Gene editing and designer babies experiments face global moratorium

Researchers track effects of epigenetic marks carried by sperm chromosomes

Androgen receptor plays vital role in regulating multiple mitochondrial processes

Study illuminates how hot spots of genetic variation evolved in the human genome

Gene medication shows promise to treat spinal cord injuries

World's oldest semen viable for artificial insemination

Promising gene therapy could restore vision in humans

Natural speed limit on DNA replication sets pace for life's first steps

Study describes epigenetic loss that changes how cells obtain energy from cancer

An Insider’s Guide to the chemagic™ Prime™ Junior Instrument

Rice University bioscientists reveal danger of vitamin B12 deficiency

New method for on-the-spot genome analysis

Scientists introduce a simple, reliable method for universal isothermal DNA amplification

DNAnexus launches innovative clinico-genomic cohort browser to accelerate research and discovery

Experts issue new guidelines for use of genetic testing in psychiatric care

CAR-T cell therapy could be on the horizon for patients with lupus

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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