Genomics

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Scientists use CRISPR to reveal the secret life of antimicrobial peptides

When it comes to the immune system, we usually think about lymphocytes like B and T cells or macrophages going on constant seek-and-destroy missions against invading pathogens like bacteria and viruses.

26 Feb 2019

Scientists report new and improved method to detect chemical modifications to DNA

Ludwig Cancer Research scientists report in the current issue of Nature Biotechnology a new and improved method to detect chemical modifications to DNA.

26 Feb 2019

Researchers uncover possibility of acoustic side-channel attack on DNA synthesis process

During the DNA synthesis process in a laboratory, recordings can be made of the subtle, telltale noises made by synthesis machines. And those captured sounds can be used to reverse-engineer valuable, custom-designed genetic materials used in pharmaceuticals, agriculture and other bioengineering fields.

25 Feb 2019

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

As the biomedical field races to develop therapies based on an individual's genetic makeup, a City of Hope scientist and his colleagues found that some commercial cell lines used for countless laboratory studies have mislabeled ancestry when it comes to minorities.

25 Feb 2019

The gene-edited twins born in China may have altered cognition and memory

A new study has fuelled further concerns over the controversial gene-editing experiment that was performed in China last year.

22 Feb 2019

UVA scientist receives $1 million award to map out submicroscopic world

A scientist at the University of Virginia School of Medicine has received a prestigious three-year, $1 million award from the William M. Keck Foundation to develop a new and better way to map out the submicroscopic world.

22 Feb 2019

Mitochondrial proteotoxicity appears to be epicentre of molecular pathogenesis

Researchers at the University of Helsinki uncovered the mechanisms for a novel cellular stress response arising from the toxicity of newly synthesized proteins.

22 Feb 2019

Researchers discover several genes linked to increased use of alcohol and tobacco

The use of alcohol and tobacco is closely linked to several diseases, and is a contributing factor in many deaths.

21 Feb 2019

Study quantifies hepatic and intestinal mRNA expression of Ugt isoforms in rats

In pharmaceutical companies, rats are used commonly in nonclinical studies to investigate the safety, efficacy, and pharmacokinetic profiles of drug candidates before they are entered into clinical studies. Most compounds administered via the oral route are metabolized in the liver and intestine, so the metabolism is a key determinant of pharmacokinetics.

20 Feb 2019

Researchers unlock the secret behind reproduction of fish called ‘Mary’

A female stickleback fish, nick-named 'Mary', has produced offspring from eggs that appear to have been fertilized while they were still inside her, according to scientists at the University of Nottingham.

20 Feb 2019

Mogrify to accelerate novel IP and cell therapies using $3.7m USD funding

Mogrify today announced a second close on its seed funding, bringing the total raised to $3.7 million USD, and the appointment of Darrin Disley as CEO.

20 Feb 2019

Researchers engineer stem cell with ‘suicide genes’ to induce cell death in all but beta cells

Researchers have been advancing methods to generate insulin-producing beta cells from pluripotent stem cells for the clinical treatment of type 1 diabetes.

20 Feb 2019

Researchers unlock plant’s secret of producing specialized metabolites

Plants are master chemists, and Michigan State University researchers have unlocked their secret of producing specialized metabolites.

20 Feb 2019

Study shows how 3D organization of genetic material helps perpetuate the species

From fathers to children, the delivery of hereditary information requires the careful packing of DNA in sperm. But just how nature packages this DNA to prepare offspring isn't clear.

19 Feb 2019

Researchers identify multiple genetic variants associated with body fat distribution

A new breakthrough from the Genetic Investigation of Anthropometric Traits consortium, which includes many public health researchers from the University of North Carolina at Chapel Hill, identifies multiple genetic variants associated with how the body regulates and distributes body-fat tissue.

18 Feb 2019

CRISPR technology creates pluripotent stem cells that are 'invisible' to the immune system

UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally "invisible" to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants.

18 Feb 2019

IDT expands its courier zones in the UK

As an advocate for researchers in the genomics age, Integrated DNA Technologies (IDT) is expanding its courier zones to ensure that the highest-fidelity oligos are available in less time and at the same price, to more customers.

From Integrated DNA Technologies 15 Feb 2019

Scientists shed light on damaging cell effects linked to aging

Some of the damaging cell effects linked to aging could be prevented by manipulating tiny parts of cells, a study shows.

14 Feb 2019

Whole-genome sequencing and sharing real-time data could limit spread of foodborne bacteria

Employing advanced genetic-tracing techniques and sharing the data produced in real time could limit the spread of bacteria -- Bacillus cereus -- which cause foodborne illness, according to researchers who implemented whole-genome sequencing of a pathogen-outbreak investigation.

14 Feb 2019

Study: Prime real estate is determined by previous owner in the squirrel world

A young squirrel lucky enough to take over territory from an adult male squirrel is like a teenager falling into a big inheritance, according to a new University of Guelph study.

14 Feb 2019

Genomics

Scientists use CRISPR to reveal the secret life of antimicrobial peptides

Scientists report new and improved method to detect chemical modifications to DNA

Researchers uncover possibility of acoustic side-channel attack on DNA synthesis process

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

The gene-edited twins born in China may have altered cognition and memory

UVA scientist receives $1 million award to map out submicroscopic world

Mitochondrial proteotoxicity appears to be epicentre of molecular pathogenesis

Researchers discover several genes linked to increased use of alcohol and tobacco

Study quantifies hepatic and intestinal mRNA expression of Ugt isoforms in rats

Researchers unlock the secret behind reproduction of fish called ‘Mary’

Mogrify to accelerate novel IP and cell therapies using $3.7m USD funding

Researchers engineer stem cell with ‘suicide genes’ to induce cell death in all but beta cells

Researchers unlock plant’s secret of producing specialized metabolites

Study shows how 3D organization of genetic material helps perpetuate the species

Researchers identify multiple genetic variants associated with body fat distribution

CRISPR technology creates pluripotent stem cells that are 'invisible' to the immune system

IDT expands its courier zones in the UK

Scientists shed light on damaging cell effects linked to aging

Whole-genome sequencing and sharing real-time data could limit spread of foodborne bacteria

Study: Prime real estate is determined by previous owner in the squirrel world

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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