Genomics

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Innovative super minigene to revolutionize spinal muscular atrophy research

Ravindra Singh has spent years studying a gene that when missing or mutated causes spinal muscular atrophy (SMA), a deadly disease that's among the most common genetic disorders in children.

13 Mar 2024

Protein Kdm1a plays a crucial role in preserving neuronal identity, study shows

Epigenetic processes allow different cell types to emerge from a single genome. Throughout development, cells differentiate and acquire distinct characteristics by expressing the same genome in different ways.

12 Mar 2024

MIT researchers develop new method to quickly screen cancer-associated genetic mutations

Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways - some mutations simply replace one DNA nucleotide with another, while others insert or delete larger sections of DNA.

12 Mar 2024

Unveiling the molecular mechanism responsible for crossover interference during meiosis

Movies such as 'X-Men,' 'Fantastic Four,' and 'The Guardians,' which showcase vibrant mutant heroes, have captivated global audiences.

7 Mar 2024

"Copy-paste" genetic mechanism increases the genetic diversity of malaria parasite

By dissecting the genetic diversity of the most deadly human malaria parasite – Plasmodium falciparum – researchers at EMBL's European Bioinformatics Institute (EMBL-EBI) have identified a mechanism of 'copy-paste' genetics that increases the genetic diversity of the parasite at accelerated time scales.

7 Mar 2024

Inherited genetic factors may predict elevated risk of new cancers among childhood cancer survivors

Common inherited genetic factors that predict cancer risk in the general population may also predict elevated risk of new cancers among childhood cancer survivors, according to a study led by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health.

7 Mar 2024

New interdisciplinary center aims to spark developments in synthetic genomics

Applying and developing new technologies for DNA synthesis to pave the way for producing entire artificial genomes - that is the goal of a new interdisciplinary center that is being established at Heidelberg University, Karlsruhe Institute of Technology (KIT), and Johannes Gutenberg University Mainz (JGU). The aim of the Center for Synthetic Genomics is to spark new developments in synthetic genomics through basic research and technology development using methods of artificial intelligence.

6 Mar 2024

Genetic study reveals insights into ancestry-associated differences in type 2 diabetes

The development and progression of type 2 diabetes are affected by numerous biological processes, such as the body's response to insulin, the health of insulin-producing pancreatic beta cells, and the functioning of metabolic pathways.

6 Mar 2024

New insights into the evolution of genomic imprinting

Some of our genes can be expressed or silenced depending on whether we inherited them from our mother or our father.

6 Mar 2024

Key gene found to prevent muscle breakdown in muscular dystrophy

A specific gene may play a key role in new treatments that prevent muscle in the body from breaking down in serious muscle diseases, muscular dystrophies.

6 Mar 2024

MGI Tech and Eurofins genomics partner to elevate precision health with revolutionary DNBSEQ-T20×2 Sequencer and Related Technologies

MGI Tech, a company committed to building core tools and technology to lead life science, today proudly announced a milestone collaboration with Eurofins Genomics Europe Genotyping A/S (“Eurofins Genomics”), which has placed a corporate order of the revolutionary DNBSEQ-T20×2 (“T20”) ultra-high throughput sequencer, along with the genomics data center ZTRON Appliance and a range of MGI’s state-of-the-art laboratory automation products and systems.

From MGI 6 Mar 2024

Harvard's Catherine Brownstein's Multi-Omics Approach: A New Horizon for Understanding Rare Pediatric Disorders

Catherine Brownstein, MPH, PhD, an esteemed Assistant Professor at Harvard Medical School and an investigator at Boston Children's Hospital.

From Society for Laboratory Automation and Screening (SLAS) 6 Mar 2024

Novel screening system reveals sperm cell development and health at the molecular level

A novel screening system developed at Kyoto University enables researchers to investigate sperm cell development and health at the molecular level.

5 Mar 2024

Unlocking the role of lncREST RNA in DNA replication and repair

Researchers at Cima Universidad de Navarra have discovered that a ribonucleic acid that does not contain information to make proteins (long non-coding RNA) plays a crucial role in signalling and repairing errors in DNA replication during cell division.

4 Mar 2024

RAD51 protein identified as a key player in preventing DNA re-replication

Every time a cell divides, its DNA is duplicated so that the two daughter cells have the same genetic material as their parent.

4 Mar 2024

AI-powered transfer learning approach predicts gene perturbations that transform cell behavior

Technological advances in gene sequencing and computing have led to an explosion in the availability of bioinformatic data and processing power, respectively, creating a ripe nexus for artificial intelligence (AI) to design strategies for controlling cell behavior.

4 Mar 2024

New scSNV-seq technique unveils genetic drivers of diseases like cancer and Alzheimer's

Scientists have developed a new screening tool to uncover how genetic changes affect gene activity and can lead to diseases such as cancer, autoimmunity, neurodegeneration and cardiovascular disease. This new tool enables the investigation of thousands of DNA mutations identified by genetic studies in one experiment, guiding the development of advanced diagnostics and treatments.

4 Mar 2024

New ISS investigation expands genes in space toolkit for student spaceflight experiments

For nearly a decade, Genes in Space™ has challenged students to develop spaceflight experiments that use biotechnology to address spaceflight challenges.

4 Mar 2024

Prioritizing biologically motivated approaches in Mendelian randomization studies

Mendelian randomization, a powerful tool in medical research, helps us understand whether certain factors truly cause disease.

1 Mar 2024

Novel genetic mechanisms of tetracycline resistance in gut bacteria discovered

Antibiotic resistance is a significant and growing medical problem worldwide. Researchers at the Marine Biological Laboratory (MBL) and collaborators have found a novel genetic arrangement that may help a common bacterium in the human gut, Bacteroides fragilis, protect itself from tetracycline, a widely used antibiotic.

1 Mar 2024

Genomics

Innovative super minigene to revolutionize spinal muscular atrophy research

Protein Kdm1a plays a crucial role in preserving neuronal identity, study shows

MIT researchers develop new method to quickly screen cancer-associated genetic mutations

Unveiling the molecular mechanism responsible for crossover interference during meiosis

"Copy-paste" genetic mechanism increases the genetic diversity of malaria parasite

Inherited genetic factors may predict elevated risk of new cancers among childhood cancer survivors

New interdisciplinary center aims to spark developments in synthetic genomics

Genetic study reveals insights into ancestry-associated differences in type 2 diabetes

New insights into the evolution of genomic imprinting

Key gene found to prevent muscle breakdown in muscular dystrophy

MGI Tech and Eurofins genomics partner to elevate precision health with revolutionary DNBSEQ-T20×2 Sequencer and Related Technologies

Harvard's Catherine Brownstein's Multi-Omics Approach: A New Horizon for Understanding Rare Pediatric Disorders

Novel screening system reveals sperm cell development and health at the molecular level

Unlocking the role of lncREST RNA in DNA replication and repair

RAD51 protein identified as a key player in preventing DNA re-replication

AI-powered transfer learning approach predicts gene perturbations that transform cell behavior

New scSNV-seq technique unveils genetic drivers of diseases like cancer and Alzheimer's

New ISS investigation expands genes in space toolkit for student spaceflight experiments

Prioritizing biologically motivated approaches in Mendelian randomization studies

Novel genetic mechanisms of tetracycline resistance in gut bacteria discovered

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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