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Antimalarial drug enhances effect of aminoglycosides in genetic disorders

The antimalarial drug mefloquine could help treat genetic diseases such as cystic fibrosis, Duchenne muscular dystrophy, as well as some cancers.

23 Apr 2025

Electronic alerts could improve survival for patients with severe aortic stenosis

A new method of alerting clinical care providers holds promise for increasing treatment and improving survival for patients with severe aortic stenosis (AS), a valvular heart condition that can be deadly when left untreated.

23 Apr 2025

Dementia costs in the United States reach record high in 2025

The total economic burden of Alzheimer's disease and related dementias in the United States will reach $781 billion this year, according to new USC-led research.

23 Apr 2025

Scientists uncover surprising new link between gut health and blood cancer risk

Scientists at Cincinnati Children's along with an international team of researchers have discovered a surprising new connection between gut health and blood cancer risk-one that could transform how we think about aging, inflammation, and the early stages of leukemia.

23 Apr 2025

New approach targets cell surface protein to treat leukemia and solid tumors

In 2021, research led by Ryan Flynn, MD, PhD, and his mentor, Nobel laureate Carolyn Bertozzi, PhD, opened a new chapter in biology, characterizing a new kind of player on the cell surface: glycoRNAs.

23 Apr 2025

New recommendations for the treatment of familial Mediterranean fever

In 2016, EULAR - The European Alliance of Associations for Rheumatology - published recommendations on the treatment of familial Mediterranean fever (FMF). Since then, new evidence has become available, so the recommendations have been reviewed and updated.

23 Apr 2025

Emotional empathy may be preserved in people with Alzheimer's disease

People with Alzheimer's disease may retain their ability to empathize, despite declines in other social abilities, finds a new study led by University College London (UCL) researchers.

23 Apr 2025

Hyperbaric oxygen therapy brings long-term relief after cancer radiation

Hyperbaric oxygen treatment provides long-term relief for patients suffering from late radiation-induced injuries after treatment of cancer in the lower abdominal area.

23 Apr 2025

DT-109 shows promise in treating atherosclerosis and liver disease

A drug candidate, previously successful at treating severe fatty liver disease, reduces atherosclerosis - a primary driver of cardiovascular death worldwide - in large mammals, a study suggests.

23 Apr 2025

Biodesix partner, Friends of Cancer Research, publishes data in Clinical Cancer Research, demonstrating strong association between ctDNA changes and treatment outcomes for patients with solid tumor types

Biodesix, Inc, a leading diagnostics solutions company, and Bio-Rad Laboratories, a global leader in life science research and diagnostics products, contributed to new research findings from Friends of Cancer Research's (Friends') ctMoniTR Project, recently published in Clinical Cancer Research (CCR). The findings demonstrate a strong association between changes in levels of circulating tumor DNA (ctDNA) and treatment outcomes, offering the potential for integration of ctDNA analysis in therapeutic development programs, and clinical cancer care.

23 Apr 2025

DASH diet and salt reduction work together to reduce cardiovascular risk

Reducing dietary sodium and following the DASH diet each lower 10-year risk of atherosclerotic cardiovascular disease, with the greatest benefit when combined. This effect is especially strong for women, Black adults, and those with stage 2 hypertension.

23 Apr 2025

Mediterranean diet lowers breast cancer risk by 13%, postmenopausal women benefit most

A new meta-analysis of 31 observational studies finds that adherence to the Mediterranean diet is associated with a 13% lower risk of breast cancer in women, particularly among postmenopausal populations. The protective effect was strongest in Asian countries and in case-control study designs.

22 Apr 2025

Interferon regulatory factor 8 identified as key driver of liver fat buildup in NAFLD

Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance. Interferon regulatory factor 8 (IRF8) is well known for its roles in immune cell differentiation and tumor pathogenesis; however, its role in regulating glucose homeostasis and lipid metabolism remains unclear.

22 Apr 2025

Why skin shame matters more than symptoms in chronic skin conditions

A new study in Scientific Reports reveals that skin shame is a key psychological burden for people with atopic dermatitis and psoriasis. It significantly affects quality of life, even more than anxiety or depression, especially when disease severity is high.

22 Apr 2025

Genetic susceptibility to schizophrenia associated with thinner retinas

A new study led by the University of Zurich has shown that evidence of genetic susceptibility to schizophrenia can be found in the retina. This finding could help improve the early detection of the disorder.

22 Apr 2025

AI tool helps GPs spot lung cancer risk months earlier

GPs may soon be able to identify patients with an increased risk of lung cancer up to 4 months earlier than is currently the case.

22 Apr 2025

Carotid artery plaque contains elevated micronanoplastics

People with plaque in the blood vessels of their neck have a higher amount of tiny plastic particles in those vessels compared to people with healthy arteries.

22 Apr 2025

Tulane researchers identify a potential new way to treat idiopathic pulmonary fibrosis

Researchers at Tulane University have identified a potential new way to treat idiopathic pulmonary fibrosis (IPF), a deadly and currently incurable lung disease that affects more than 3 million people worldwide.

22 Apr 2025

Study reveals how medulloblastoma spreads and grows on the leptomeninges

Researchers at Baylor College of Medicine, Texas Children's Hospital, the Hospital for Sick Children in Toronto and collaborating institutions reveal in Nature Cell Biology a strategy that helps medulloblastoma, the most prevalent malignant brain tumor in children, spread and grow on the leptomeninges, the membranes surrounding the brain and spinal cord.

22 Apr 2025

Can a plant-based diet help prevent breast cancer?

A case-control study in Iranian women found that higher adherence to a healthy plant-based diet significantly reduces breast cancer risk in postmenopausal women and those with a BMI under 25. In contrast, high intake of unhealthy plant-based foods raised risk in premenopausal women.

22 Apr 2025