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Spider brain studies lead to breakthrough in understanding human brain diseases

Researchers from Saint Michael's College and the University of Vermont have made a groundbreaking new discovery that provides a better understanding of how Alzheimer's disease develops in the human brain.

4 Dec 2024

L-arginine shows potential in treating spinocerebellar ataxia type 6

A team led by Specially Appointed Associate Professor Tomohiko Ishihara and Professor Osamu Onodera at Niigata University, along with Professor Yoshitaka Nagai at Kindai University, conducted a randomized, double-blind trial on the efficacy and safety of L-arginine in treating Spinocerebellar ataxia type 6 (SCA6).

3 Dec 2024

Type 2 diabetes doubles infection-related mortality and exposes gaps in health reporting

People with type 2 diabetes face a significantly higher risk of infection-related deaths, particularly in younger age groups, with infections accounting for 13% of deaths compared to 1.2% in conventional records.

3 Dec 2024

Holistic lifestyle interventions outshine drugs in preventing cardiometabolic diseases

Comprehensive lifestyle interventions prevent cardiometabolic diseases effectively but face challenges in routine care and require supportive policies for lasting impact.

3 Dec 2024

Behavioral chaos in Alzheimer’s disease mice decoded by machine learning

Researchers use machine learning to identify behavioral disruptions in Alzheimer’s disease mouse models, highlighting a potential therapeutic target in fibrinogen-microglia interactions.

3 Dec 2024

Serum protein panel test can help identify cardiomyopathy risk in childhood cancer survivors

Early disease detection is beneficial for securing the best possible outcomes for patients. But finding noninvasive, effective ways to predict disease risk is a tremendous challenge.

3 Dec 2024

Study cracks the cold case of immunotherapy resistance

A study from the University of Michigan Health Rogel Cancer Center may have, at last, cracked the cold case of immunotherapy resistance.

3 Dec 2024

New algorithm identifies tumor cells driving aggressive cancer growth

The first computer algorithm capable of identifying which tumor cells are driving aggressive cancer growth has been developed by Cancer Research UK-funded scientists from UCL and The Francis Crick Institute.

3 Dec 2024

Spinal manipulation linked to lower butalbital use in tension-type headaches

A team of researchers led by University Hospitals Connor Whole Health have identified an association between spinal manipulative therapy (SMT) and a reduced likelihood of butalbital prescription and medication overuse headache (MOH) for patients experiencing tension-type headaches (TTH). Their retrospective study, published in Health Science Reports, includes more than 6,200 patients from a national US database spanning 2013 to 2024.

3 Dec 2024

New immune therapy improves survival and reduces tumor burden in glioblastoma

The Wistar Institute's David B. Weiner, Ph.D. - Executive Vice President, director of the Vaccine & Immunotherapy Center and W.W. Smith Charitable Trust Distinguished Professor in Cancer Research - and his lab have successfully tested a new immune therapy that, in preclinical lab testing, reliably improves survival and reduces tumor burden in glioblastoma.

3 Dec 2024

Researchers aim to uncover causes of acquired hearing loss and find potential therapies

With a new five-year, $3.2 million grant from the National Institute on Deafness and Other Communications Disorders, researchers at Case Western Reserve University and Mass Eye and Ear will study what causes acquired hearing loss (AHL) and seek new ways to protect against it.

3 Dec 2024

Study finds T cell exhaustion in chronic fatigue syndrome patients

Chronic fatigue syndrome creates conditions where pathogen-killing immune T cells become exhausted, according to a new Cornell University study.

3 Dec 2024

Report highlights increasing use of targeted therapies before surgery for cancer treatment

Breast, bladder, and pancreatic cancers are increasingly being treated with a broad range of therapies before a patient undergoes surgery, and cancer stage at diagnosis continues to be a leading factor in determining a person's survival rate for all types of cancer, according to the first-ever annual cancer report from the National Cancer Database (NCDB) of the American College of Surgeons (ACS) Cancer Programs.

3 Dec 2024

How carrageenan affects insulin resistance

A randomized controlled trial found that carrageenan, a common food additive, may cause subclinical inflammation and insulin resistance in overweight individuals, mediated by gut permeability and inflammation. Effects were linked to BMI but not observed in non-overweight participants during short-term exposure.

3 Dec 2024

High blood sugar impairs brain health even without diabetes

A study by Baycrest found that high blood sugar may impair brain health even in people without diabetes.

3 Dec 2024

Baycrest study discovers role of thalamus in post-stroke recovery

A recent study by Baycrest reveals that an area of the brain distinct from the stroke lesion may play a significant role in causing the life-altering symptoms survivors are often left with, which can include severe challenges with speech, mobility and cognition.

3 Dec 2024

UTHealth study could set new standards for treating acromioclavicular joint injuries in athletes

A new UTHealth Houston study focused on finding the best surgical technique for reconstruction of the acromioclavicular joint (ACJ), where the collarbone meets the shoulder blade, has the potential to enhance recovery and long-term shoulder health for young athletes.

3 Dec 2024

Study finds no impact of high vitamin D doses on type 2 diabetes prevention

Using significantly higher doses of vitamin D than recommended for five years did not affect the incidence of type 2 diabetes in elderly men and women, according to a new study from the University of Eastern Finland.

3 Dec 2024

Study sheds light on brain circuit behind auditory hallucinations in schizophrenia

Voice experiments in people with epilepsy have helped trace the circuit of electrical signals in the brain that allow its hearing center to sort out background sounds from their own voices.

3 Dec 2024

Loss of empathy in frontotemporal dementia linked to brain activity changes

Patients with frontotemporal dementia often lack the ability to empathize. A study at Karolinska Institutet has now shown that these patients do not show the same brain activity as healthy individuals when they witness the pain of others, a finding that it is hoped will increase understanding of this specific dementia disease.

3 Dec 2024