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FDA grants orphan-drug designation to Genoa's pirfenidone for treatment of IPF disease

Genoa Pharmaceuticals, the leader in inhaled medicines for pulmonary fibrosis, today announced the U.S. Food and Drug Administration (FDA) has granted orphan-drug designation to Genoa for the use of pirfenidone in their lead program - inhaled GP-101 for the treatment of IPF.

5 Aug 2014

Mutated gene related to diabetes in Mexicans, shows research

The research team, directed by Dr. Karol Estrada, analyzed genetic sequencing of 8000 Mexicans and found a mutated gene related to diabetes in 30% of mestizos and in half the indigenous population.

5 Aug 2014

New project aims to develop unique database on frailty and dementia

What is the relationship between frailty and dementia? Many studies acknowledge that frailty and dementia often coexist, but little research has been done on why that is the case.

5 Aug 2014

Researchers postulate similarities between changes in cells and origins of triple negative breast cancer

Healthy breast cells may be able to reinvent themselves -- some have the flexibility to change after they are mature -- which leads researchers to postulate that similarities exist between this occurrence and the origins of a particularly aggressive type of breast cancer.

5 Aug 2014

Persons with ASD have trouble in noticing their movement imitated by others

A Japanese research group led by Prof Norihiro Sadato, a professor of the National Institute for Physiological Sciences (NIPS), National Institutes of Natural Sciences (NINS), has found that people with autism spectrum disorders (ASD) have decreased activity in an area in the brain critical for understanding if his/her movement was imitated by others.

5 Aug 2014

Overweight people who suffer from hypoventilation can have low levels of oxygen during air travel

Severely overweight people who suffer from hypoventilation can have abnormally low levels of oxygen (hypoxaemia) in their blood during air travel as a result of reduced atmospheric pressure in the cabin of aircrafts.

5 Aug 2014

Ragweed pollen reported for first time in 2014 allergy reporting season

Later summer triggers ragweed allergies in 10 to 20 percent of Americans and today spells misery for those with sensitive systems. Ragweed pollen was reported for the first time in the 2014 allergy reporting season, causing a pollen vortex of sneezing, itching and headaches for Midwesterners.

5 Aug 2014

Researchers receive $435K to study how environmental factors affect genes that cause autism

Over the last decade, autism research has been primarily focused on finding genes that may "cause" autism. However, little information exists on gene-environment interactions that may increase risk for autism.

5 Aug 2014

Acupuncture at Waiguan can activate several brain regions in patients with ischemic stroke

Both acupuncture at Waiguan (SJ5) and sham acupuncture can activate/deactivate several brain regions in patients with ischemic stroke, but there are some difference in Brodmann areas 4, 6, 8, Brodmann areas 7, 39, 40, Brodmann areas 18, 19, 22 and Brodmann areas 13, 24, 32, 28.

5 Aug 2014

Scientists spearhead new £6 million initiative to find better ways to prevent cancer

Queen's University scientists are helping to spearhead a new £6 million initiative to find better ways to prevent cancer.

5 Aug 2014

Triple therapy for glioblastoma has prolonged survival of mice with brain cancers

A triple therapy for glioblastoma, including two types of immunotherapy and targeted radiation, has significantly prolonged the survival of mice with these brain cancers, according to a new report by scientists at the Johns Hopkins Kimmel Cancer Center.

5 Aug 2014

Subtle changes in gene can predict how brain reacts to stress

Scientists studying depression in teens have discovered that subtle changes in a gene can predict how the brain reacts to stress, which can cause such health issues as depression, post-traumatic stress disorder and obesity.

5 Aug 2014

Positive emotions may play exacerbating role in fueling anorexia nervosa

Positive emotions - even those viewed through a distorted lens - may play an exacerbating role in fueling eating disorders like anorexia nervosa, which has a death rate 12 times higher for females between the ages of 15 and 24 than all other causes of death combined, according to a Rutgers study.

4 Aug 2014

Doctor offers 5 tips for reducing risk of deep vein thrombosis

For most people, a well-paying white-collar job definitely beats the kind of hard physical labor that can often lead to a variety of health problems as we get older – and we all love our modern conveniences.

4 Aug 2014

Research results in new insights into clinical depression

Research led by the University of Adelaide has resulted in new insights into clinical depression that demonstrate there cannot be a "one-size-fits-all" approach to treating the disease.

4 Aug 2014

New, promising approach combines metformin and SGLT2 inhibitors to treat diabetes

Various active substances in oral antidiabetic agents are frequently combined in the treatment of diabetes in order to achieve an effective reduction in the blood sugar. A new, very promising approach combines the substances metformin and SGLT2 inhibitors, the latter were just approved in 2012.

4 Aug 2014

5-LO enzyme plays important role in the survival of leukaemic AML stem cells

Despite improved therapy, only one out of every two adult patients survive acute myeloid leukaemia (AML). The mean survival time for this disease, which predominantly occurs in the elderly, is less than a year for patients over 65 years. It is assumed that leukaemic stem cells, which cannot be completely eliminated during treatment, are the origin of relapse.

4 Aug 2014

Study shows new potential mechanism to better understand AD in African Americans

Researchers from Boston University School of Medicine report that two rare variants in the AKAP9 gene significantly increase the risk of Alzheimer's disease (AD) in African-Americans.

4 Aug 2014

Phase 3 ASPIRE clinical trial meets primary endpoint of progression-free survival

Amgen and its subsidiary, Onyx Pharmaceuticals, Inc., today announced that a planned interim analysis demonstrated that the Phase 3 clinical trial ASPIRE (CArfilzomib, Lenalidomide, and DexamethaSone versus Lenalidomide and Dexamethasone for the treatment of PatIents with Relapsed Multiple MyEloma) met its primary endpoint of progression-free survival (PFS).

4 Aug 2014

Neuralstem doses final patient with NSI-566 stem cells in Phase II trial

Neuralstem, Inc. announced that the final patient was treated in its Phase II trial using NSI-566 spinal cord-derived neural stem cells in the treatment of amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease).

4 Aug 2014

Medical Condition News

FDA grants orphan-drug designation to Genoa's pirfenidone for treatment of IPF disease

Mutated gene related to diabetes in Mexicans, shows research

New project aims to develop unique database on frailty and dementia

Researchers postulate similarities between changes in cells and origins of triple negative breast cancer

Persons with ASD have trouble in noticing their movement imitated by others

Overweight people who suffer from hypoventilation can have low levels of oxygen during air travel

Ragweed pollen reported for first time in 2014 allergy reporting season

Researchers receive $435K to study how environmental factors affect genes that cause autism

Acupuncture at Waiguan can activate several brain regions in patients with ischemic stroke

Scientists spearhead new £6 million initiative to find better ways to prevent cancer

Triple therapy for glioblastoma has prolonged survival of mice with brain cancers

Subtle changes in gene can predict how brain reacts to stress

Positive emotions may play exacerbating role in fueling anorexia nervosa

Doctor offers 5 tips for reducing risk of deep vein thrombosis

Research results in new insights into clinical depression

New, promising approach combines metformin and SGLT2 inhibitors to treat diabetes

5-LO enzyme plays important role in the survival of leukaemic AML stem cells

Study shows new potential mechanism to better understand AD in African Americans

Phase 3 ASPIRE clinical trial meets primary endpoint of progression-free survival

Neuralstem doses final patient with NSI-566 stem cells in Phase II trial

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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