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TSRI study shows how aging affects brain's neural circuitry

How aging affects communication between neurons is not well understood, a gap that makes it more difficult to treat a range of disorders, including Alzheimer's and Parkinson's disease.

23 Jan 2014

Study identify key barriers associated with lack of cancer screenings in Appalachian women

A new study by University of Kentucky researchers shows that women who never or rarely screen for breast cancer are also unlikely to receive screening for cervical cancer. The study also identified four key barriers independently associated with the lack of these cancer screenings in Appalachian women.

23 Jan 2014

Structural biologists advance efforts to develop new drugs targeting NMDA receptors in brain

Structural biologists at Cold Spring Harbor Laboratory (CSHL) and collaborators at Emory University have obtained important scientific results likely to advance efforts to develop new drugs targeting NMDA receptors in the brain.

23 Jan 2014

Number of cancer stem cells in tumor might inaccurately estimate tumor's recurrence or progression

New research from The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) suggests that it may be the quality of cancer stem cells rather than their quantity that leads to better survival in certain patients with oral cancer.

23 Jan 2014

Personalized vaccine therapy contributes to increased survival rate in IL2-treated metastatic melanoma

Metastatic melanoma has a poor prognosis, but treatment with high-dose interleukin-2 (IL2) can extend survival. Now, a combination of IL2 therapy and activation of patients' immune systems using personalized vaccines made from their own tumor cells has been shown to improve survival rates even more than IL2 alone, according to a new article in Cancer Biotherapy and Radiopharmaceuticals, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

23 Jan 2014

EORTC trial follow-up shows chemo-radiotherapy for patients with rectal cancer does not improve survival

Appearing in Lancet Oncology, long term results of EORTC trial 22921 with 10.4 years median follow-up show that 5-FU (fluorouracil) based adjuvant chemotherapy after preoperative (chemo)-radiotherapy for patients with cT3-resectable T4 M0 rectal cancer does not improve survival or disease-free survival.

23 Jan 2014

Targeting symptoms, rather than disorders, might help reduce work impact of mental health issues

Symptoms such as insomnia and emotional distress account for much of the work impact of mental health problems such as depression and anxiety, reports a study in the February issue of Medical Care.

23 Jan 2014

MD Anderson collaborates with Johnson & Johnson to develop immunology-based cancer treatments

The University of Texas MD Anderson Cancer Center will collaborate with Johnson & Johnson Innovation, LLC, and its affiliate Janssen Biotech, Inc., to develop immunology-based cancer treatments through the MD Anderson Moon Shots Program immunotherapy platform.

23 Jan 2014

Hydroxytyrosol in olive oil may help reduce risk of breast cancer

A major component of olive oil, hydroxytyrosol, is the subject of a Houston Methodist study of women who are at increased risk of developing breast cancer. The study focuses on the changes in breast density after one year of treatment and is the first of its kind in the United States.

23 Jan 2014

Hispanic women twice as likely as white women to be affected by vulvodynia

Hispanic women surveyed in the metro Detroit area were twice as likely as white women to be affected by vulvodynia, unexplained vulvar pain that can make sex, tampon use or even sitting excruciating. Meanwhile, the condition affected half as many black women, new University of Michigan research shows.

23 Jan 2014

Obese kids exposed to high levels of air pollutants are nearly 3 times as likely to have asthma

Obese children exposed to high levels of air pollutants were nearly three times as likely to have asthma, compared with non-obese children and lower levels of pollution exposure, report researchers at Columbia University Medical Center (CUMC).

23 Jan 2014

ICR, Nuevolution and CRT partner to identify novel drug candidates for cancer treatment

The Institute of Cancer Research, London, Cancer Research Technology, London and Nuevolution A/S, Copenhagen have entered into a drug discovery collaboration to identify novel lead candidates for cancer treatment.

23 Jan 2014

Chinese and American researchers introduce new approach to gene therapy

Resistance of tumor cells toward multiple cytostatic drugs is a serious problem in cancer treatment. In the journal Angewandte Chemie, a team of Chinese and American researchers has now introduced a new approach to gene therapy that could counter this problem: The gene that codes for resistance is “silenced” through the use of an ingenious nanocomplex.

22 Jan 2014

New scientific article shows that Patrys' PAT-SC1 safe, well-tolerated in gastric cancer patients

Patrys Limited, a clinical stage biotechnology company is pleased to announce the publication of a new scientific article regarding its product PAT-SC1 in the Oncology Reports journal. The article is currently available online and will be included in a future print edition of the journal.

22 Jan 2014

UC researchers receive more than $1M grant to study complex traumatic injuries of warfare

Trauma and critical care researchers at the University of Cincinnati (UC) have received more than $1 million from the United States Air Force in a recent set of grant awards to study how air medical evacuation affects patients, medical professionals and medical equipment.

22 Jan 2014

New oral drug appears to offer hope for fighting indolent non-Hodgkin lymphoma

Slow-growing, or indolent, non-Hodgkin lymphomas are difficult to treat, with most patients relapsing repeatedly and the disease becoming increasingly resistant to therapy over time.

22 Jan 2014

Adverse events for patients treated for heart attack and heart failure have declined, study finds

Adverse events for patients being treated for heart attack and heart failure have declined, according to a new study published in the January 23 issue of the New England Journal of Medicine. However, the analysis funded by the Agency for Healthcare Research and Quality found that there has not been a significant decrease in adverse events for patients being treated for pneumonia and those who are recovering from surgery.

22 Jan 2014

Lack of SIRT1 protein in the liver leads to lower levels of liver FGF21

A new study led by Boston University School of Medicine demonstrates that the abnormal metabolism linked to obesity could be regulated in part by the interaction of two metabolic regulators, called the NAD-dependent deacetylase SIRT1 and fibroblast growth factor 21 (FGF21). Using experimental models, the researchers found that a lack of SIRT1 protein in the liver led to lower levels of a liver secreted protein FGF21, which resulted in an increased likelihood of developing fatty liver disease and obesity.

22 Jan 2014

High-protein diet increases chance of developing kidney stones, other renal diseases

High-protein diets, like the popular Dr. Dukan diet, increase the long-term risk of developing kidney disease and have a negative effect on renal urinary and morphological markers. What's more, they may promote serious pathologies like nephrolithiasis (calcium kidney stones) because they drastically reduce urinary citrate (an inhibitor of calcium salt crystallization) and urinary pH, and increase urinary calcium (to compensate for the metabolic acidity caused by excess protein).

22 Jan 2014

Research under way to develop new techniques for detecting diabetic retinopathy

Research is under way to develop new techniques for detecting diabetic retinopathy at early onset with the hope of improving prevention and treatment of this major cause of blindness.

22 Jan 2014

Medical Condition News

TSRI study shows how aging affects brain's neural circuitry

Study identify key barriers associated with lack of cancer screenings in Appalachian women

Structural biologists advance efforts to develop new drugs targeting NMDA receptors in brain

Number of cancer stem cells in tumor might inaccurately estimate tumor's recurrence or progression

Personalized vaccine therapy contributes to increased survival rate in IL2-treated metastatic melanoma

EORTC trial follow-up shows chemo-radiotherapy for patients with rectal cancer does not improve survival

Targeting symptoms, rather than disorders, might help reduce work impact of mental health issues

MD Anderson collaborates with Johnson & Johnson to develop immunology-based cancer treatments

Hydroxytyrosol in olive oil may help reduce risk of breast cancer

Hispanic women twice as likely as white women to be affected by vulvodynia

Obese kids exposed to high levels of air pollutants are nearly 3 times as likely to have asthma

ICR, Nuevolution and CRT partner to identify novel drug candidates for cancer treatment

Chinese and American researchers introduce new approach to gene therapy

New scientific article shows that Patrys' PAT-SC1 safe, well-tolerated in gastric cancer patients

UC researchers receive more than $1M grant to study complex traumatic injuries of warfare

New oral drug appears to offer hope for fighting indolent non-Hodgkin lymphoma

Adverse events for patients treated for heart attack and heart failure have declined, study finds

Lack of SIRT1 protein in the liver leads to lower levels of liver FGF21

High-protein diet increases chance of developing kidney stones, other renal diseases

Research under way to develop new techniques for detecting diabetic retinopathy

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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