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Edison Pharmaceuticals initiates Phase 2B/3 study of EPI-743 in children with Leigh syndrome

Edison Pharmaceuticals today announced the initiation of a phase 2B/3 study entitled, "A Phase 2B/3 Open-label Study of EPI-743 in Children with Leigh Syndrome" to be conducted in conjunction with Dainippon Sumitomo Pharma Co, Ltd.

10 Mar 2014

Exposure to UV light may exacerbate melanoma cells to creep outside blood vessels

Based on the pioneering work of Dr. Claire Lugassy and Dr. Raymond Barnhill at UCLA's Jonsson Comprehensive Cancer Center, a new study provides additional support for a process by which melanoma cells, a deadly form of skin cancer, can spread throughout the body by creeping like tiny spiders along the outside of blood vessels without ever entering the blood stream, and that this process is exacerbated by exposure to ultraviolet (UV) light.

10 Mar 2014

Mutations in gene associated with leukaemia may affect growth, intellectual development in children

Mutations in a gene associated with leukaemia cause a newly described condition that affects growth and intellectual development in children, new research reports.

10 Mar 2014

Erlotinib has promising potential to improve treatment for cervical cancer

A new clinical study has found that erlotinib, a targeted antitumor agent, has promising potential to improve treatment for cervical cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the results indicate that larger trials are warranted to determine whether the drug should become part of standard therapy for women with the disease.

10 Mar 2014

Tissue analysis near tumors holds promise for earlier detection, new treatments

Seemingly healthy cells may in fact hide clues that lung cancer will later develop, according to a study led by researchers at The University of Texas MD Anderson Cancer Center The research is published online in the Journal of the National Cancer Institute.

9 Mar 2014

People with type 2 diabetes have epigenetic changes on DNA

People with type 2 diabetes have epigenetic changes on their DNA that healthy individuals do not have. This has been shown in a major study by researchers at Lund University. The researchers also found epigenetic changes in a large number of genes that contribute to reduced insulin production.

9 Mar 2014

Dr. Daniel D. Von Hoff named one of ASCO's 50 Oncology Luminaries

In association with its 50th anniversary, the American Society of Clinical Oncology has named Dr. Daniel D. Von Hoff one of ASCO's 50 Oncology Luminaries, celebrating 50 doctors who over the past half-century have significantly advanced cancer care.

9 Mar 2014

Study looks at relationships between obesity, education and wealth in low- and middle-income countries

Obesity levels among women in low- and middle-income countries tend to rise in line with wealth as they purchase more energy-dense foods, but a new UCL study suggests that more educated consumers make better food choices that mitigate this effect.

9 Mar 2014

FDA-approved anti-psychotic drugs possess tumor-killing activity against glioblastoma

Researchers at the University of California, San Diego School of Medicine have discovered that FDA-approved anti-psychotic drugs possess tumor-killing activity against the most aggressive form of primary brain cancer, glioblastoma. The finding was published in this week's online edition of Oncotarget.

8 Mar 2014

Aptel Research releases newest report Patient Voices Series Rheumatoid Arthritis

Aptel Research, a specialty marketing research and consulting company that provides actionable strategic insights to the pharmaceutical and biotech industries, released its newest report Patient Voices Series Rheumatoid Arthritis (US).

8 Mar 2014

National clinical trial to test new avenue for tinnitus treatment

UT Southwestern Medical Center will take part in a national clinical trial to test a device that could provide relief for people suffering from tinnitus, a persistent buzzing or ringing sound in the ears. The device uses nervous system stimuli to rewire parts of the brain, in hopes of significantly reducing or removing tinnitus.

7 Mar 2014

BWH researchers explore newer approaches to treat Alzheimer's disease

A team of Alzheimer's disease (AD) researchers at Brigham and Women's Hospital (BWH) has been able to study the underlying causes of AD and develop assays to test newer approaches to treatment by using stem cells derived from related family members with a genetic predisposition to (AD).

7 Mar 2014

Research paper takes broader snapshot of returning soldiers' mental state

Much of the research on post-combat mental health of veterans focuses on problems like post-traumatic stress disorder (PTSD) and major depression. A paper co-authored by R. Tyson Smith, visiting assistant professor of sociology, takes an even broader snapshot of returning soldiers' mental state by focusing instead on the identity conflict many face when transitioning from soldier to civilian life and how that conflict manifests as mental distress.

7 Mar 2014

Higher levels of exposure to traffic-related air pollution linked to changes in right ventricle of the heart

Exposure to high levels of traffic-related air pollution is associated with changes in the right ventricle of the heart that may contribute to the known connection between air pollution exposure and heart disease, according to a new study.

7 Mar 2014

Scientists throw light on genetic mutation that causes particularly severe genetic disease ARVC5

The genetic disease ARVC leads to sudden cardiac death and is more common than it has been hitherto assumed. This is reported by an international team of researchers headed by Prof Dr Hendrik Milting from the Heart and Diabetes Center NRW in the "European Heart Journal".

7 Mar 2014

Research explores new diagnostic strategies to detect glaucoma

Research exploring several new diagnostic strategies to find the earliest changes in the eye to detect glaucoma is underway at the University of Alabama at Birmingham School of Optometry. One optometrist says awareness of this eye disorder is just as important as continuing to study it.

7 Mar 2014

TAZ gene represents potential target for drug therapies to treat aggressive types of breast cancer

Significance: Understanding more about how the different types of cells in breast tissue develop improves our knowledge of breast cancer. TAZ represents a potential new target for drug therapies to treat aggressive types of breast cancer.

7 Mar 2014

Doctors' unconscious biases does not affect high BP treatment for minority patients, says study

Doctors' unconscious biases favor whites but do not affect high blood pressure treatment for their minority patients, according to a University of Colorado Boulder study, even though a previous study by the same research group found that doctors' biases are reflected in lower ratings by African-American patients.

7 Mar 2014

Incyte Corporation publishes results of Phase III trial of ruxolitinib in patients with polycythemia vera

Incyte Corporation (Nasdaq: INCY) today announced that a pivotal Phase III trial of ruxolitinib compared to best available therapy in patients with polycythemia vera who are resistant to or intolerant of hydroxyurea has met its primary endpoint of achieving phlebotomy independence and reducing spleen size by 35 percent or more.

7 Mar 2014

New study shows that half the people in Hirono have PTSD symptoms

Though just two of Hirono's 5,418 residents lost their lives in Japan's mega-earthquake and tsunami, a new study shows that the survivors are struggling to keep their sanity.

7 Mar 2014

Medical Condition News

Edison Pharmaceuticals initiates Phase 2B/3 study of EPI-743 in children with Leigh syndrome

Exposure to UV light may exacerbate melanoma cells to creep outside blood vessels

Mutations in gene associated with leukaemia may affect growth, intellectual development in children

Erlotinib has promising potential to improve treatment for cervical cancer

Tissue analysis near tumors holds promise for earlier detection, new treatments

People with type 2 diabetes have epigenetic changes on DNA

Dr. Daniel D. Von Hoff named one of ASCO's 50 Oncology Luminaries

Study looks at relationships between obesity, education and wealth in low- and middle-income countries

FDA-approved anti-psychotic drugs possess tumor-killing activity against glioblastoma

Aptel Research releases newest report Patient Voices Series Rheumatoid Arthritis

National clinical trial to test new avenue for tinnitus treatment

BWH researchers explore newer approaches to treat Alzheimer's disease

Research paper takes broader snapshot of returning soldiers' mental state

Higher levels of exposure to traffic-related air pollution linked to changes in right ventricle of the heart

Scientists throw light on genetic mutation that causes particularly severe genetic disease ARVC5

Research explores new diagnostic strategies to detect glaucoma

TAZ gene represents potential target for drug therapies to treat aggressive types of breast cancer

Doctors' unconscious biases does not affect high BP treatment for minority patients, says study

Incyte Corporation publishes results of Phase III trial of ruxolitinib in patients with polycythemia vera

New study shows that half the people in Hirono have PTSD symptoms

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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