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EnVivo Pharmaceuticals starts encenicline Phase 3 study in patients with Alzheimer's disease

EnVivo Pharmaceuticals, a company dedicated to developing a broad range of novel therapies for central nervous system diseases, today announced it has initiated COGNITIV AD, a Phase 3 clinical program evaluating its novel alpha-7 (α7) potentiator, encenicline-hydrochloride (EVP-6124), in patients with Alzheimer's disease. The program is being conducted under a Special Protocol Assessment agreement with the FDA.

22 Jan 2014

Advanced melanoma treatments: an interview with Dr. James Larkin, Consultant Medical Oncologist, The Royal Marsden

Advanced melanoma affects around 2,000 people per year in the UK. Advanced melanoma describes a melanoma that has spread from its site of origin to other areas of the body.

22 Jan 2014

Long-term exposure to particulate matter linked with increased risk for heart attack

Long-term exposure to particulate matter is associated with an increased risk for heart attack. Moreover, this association can already be observed in levels of particulate exposure below the current specified European limit values.

22 Jan 2014

Study reports that being overweight makes children less active

A new study from the University of Copenhagen's OPUS Research Centre reports that being overweight makes children less active. The findings underscore that parents of overweight children have an obligation to keep their children active, as physical activity is vital for the general health of all children. The study also shows that slender children do not become overweight due to a lack of activity.

22 Jan 2014

Girls treated for Hodgkin's disease during adolescence acquire risk of developing breast cancer

Girls treated for Hodgkin's disease during adolescence acquire a considerable risk of developing breast cancer, as shown by an observational study published in the current issue of Deutsches Ärzteblatt International.

22 Jan 2014

Researchers assess familial risks for MS using population registers, health care registries

Even though multiple sclerosis is largely caused by genetic factors, the risk of patients' relatives developing the disease is lower than previously assumed. This is the conclusion of a new population registry-based study, published in the scientific journal Brain.

22 Jan 2014

EKF Diagnostics announces major breakthrough for PointMan DNA enrichment technology

EKF, announces a major breakthrough for its PointMan DNA enrichment technology for potential use in future cancer testing and treatment.

From EKF Diagnostics 22 Jan 2014

Joint research program in SMA enters initial stage of clinical development

PTC Therapeutics, Inc., the SMA Foundation, and Roche, announced today that their joint research program in Spinal Muscular Atrophy has entered the first stage of clinical development aiming to assess safety and tolerability of an oral compound in healthy volunteers.

22 Jan 2014

Increasing number of children are treated in U.S. EDs for head injuries

Although a voluntary shopping cart safety standard was implemented in the United States in 2004, the overall number and rate of injuries to children associated with shopping carts have not decreased. In fact, the number and rate of concussions/closed head injuries have continued to climb, according to a new study.

22 Jan 2014

Self-testing for HPV effective in detecting cervical cancer

Self-testing for Human Papillomavirus (HPV) - the virus that causes cervical cancer - is as effective at detecting cancer as a conventional smear test (cytology screening) even when scaled up to test large populations.

22 Jan 2014

CytRx receives FDA approval to continue dosing aldoxorubicin for patients with soft tissue sarcomas

CytRx Corporation (NASDAQ:CYTR), a biopharmaceutical research and development company specializing in oncology, today announced it has received approval from the U.S. Food and Drug Administration (FDA) to continue dosing patients with aldoxorubicin until disease progression in a planned pivotal, global Phase 3 clinical trial with aldoxorubicin as a second-line treatment for soft tissue sarcomas.

22 Jan 2014

Study ultimately could lead to development of screening test for diagnosing bladder cancer

Findings from a Loyola University Medical Center study ultimately could lead to tests to screen for and diagnose bladder cancer.

22 Jan 2014

Strategic placement of care managers in PCMHs can improve outcomes for high-risk diabetes patients

Patient centered medical homes (PCMHs) have been found to be an effective way to help care for patients with chronic diseases such as diabetes. Dr. Robert Gabbay, M.D., Ph.D., FACP, Chief Medical Officer and Senior Vice President at Joslin Diabetes Center, and his team conducted a study that shows the strategic placement of care managers in PCMHs can further improve patient outcomes for high-risk diabetes patients.

22 Jan 2014

New orthotic device could aid in rehabilitation of patients with ankle-foot disorders

A soft, wearable device that mimics the muscles, tendons and ligaments of the lower leg could aid in the rehabilitation of patients with ankle-foot disorders such as drop foot, said Yong-Lae Park, an assistant professor of robotics at Carnegie Mellon University.

22 Jan 2014

ASA's recommendations to help patients avoid unnecessary tests for chronic pain

Not prescribing opioids first or as a long-term therapy for chronic, non-cancer pain and avoiding MRIs, CTs and X-rays for low-back pain are among the tests and treatments identified by ASA that are commonly ordered but not always necessary.

22 Jan 2014

Clues of "silent thief of sight”: Glaucoma

Glaucoma is sometimes called the "silent thief of sight" because it slowly damages the eyes and can cause irreparable harm before there is any vision loss. But this disease is stealthy in more ways than one.

22 Jan 2014

Researchers demonstrate existence of an epigenetic lesion in hippocampus of Alzheimer patients

Alzheimer's disease can reach epidemic range in the coming decades, by the increasing average age of society. There are two key issues for Alzheimer's disease: there is currently no effective treatment and it has been described very few associated genetic changes (mutations) which reduces the number of targets for future therapies.

22 Jan 2014

Brain imaging via MRI scans may be useful biomarker for early detection of subtle developmental abnormalities

Researchers at Penn Medicine have generated a brain development index from MRI scans that captures the complex patterns of maturation during normal brain development.

22 Jan 2014

Longer withdrawal times during colonoscopy correlates with higher rate of polyp detection

Dartmouth-Hitchcock Norris Cotton Cancer Center (NCCC) researchers found that longer withdrawal times during a colonoscopy correlates with a higher rate of polyp detection. The study was recently published online in in the American Journal of Gastroenterology.

22 Jan 2014

Patients who arrive at hospital during off-hours are more likely to die

More people die and emergency hospital treatment takes longer for heart attack victims who arrive at the hospital during off-hours (nights and weekends), compared with patients who arrive during regular daily hours, according to a Mayo Clinic study published online in the British Medical Journal on Jan. 21.

22 Jan 2014

Medical Condition News

EnVivo Pharmaceuticals starts encenicline Phase 3 study in patients with Alzheimer's disease

Advanced melanoma treatments: an interview with Dr. James Larkin, Consultant Medical Oncologist, The Royal Marsden

Long-term exposure to particulate matter linked with increased risk for heart attack

Study reports that being overweight makes children less active

Girls treated for Hodgkin's disease during adolescence acquire risk of developing breast cancer

Researchers assess familial risks for MS using population registers, health care registries

EKF Diagnostics announces major breakthrough for PointMan DNA enrichment technology

Joint research program in SMA enters initial stage of clinical development

Increasing number of children are treated in U.S. EDs for head injuries

Self-testing for HPV effective in detecting cervical cancer

CytRx receives FDA approval to continue dosing aldoxorubicin for patients with soft tissue sarcomas

Study ultimately could lead to development of screening test for diagnosing bladder cancer

Strategic placement of care managers in PCMHs can improve outcomes for high-risk diabetes patients

New orthotic device could aid in rehabilitation of patients with ankle-foot disorders

ASA's recommendations to help patients avoid unnecessary tests for chronic pain

Clues of "silent thief of sight”: Glaucoma

Researchers demonstrate existence of an epigenetic lesion in hippocampus of Alzheimer patients

Brain imaging via MRI scans may be useful biomarker for early detection of subtle developmental abnormalities

Longer withdrawal times during colonoscopy correlates with higher rate of polyp detection

Patients who arrive at hospital during off-hours are more likely to die

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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