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HCT 1026 may help stem debilitating effects of muscular dystrophy

Cedars-Sinai Heart Institute researchers have found that an experimental compound may help stem the debilitating effects of muscular dystrophy by restoring normal blood flow to muscles affected by the genetic disorder.

9 Nov 2012

FDA accepts Merck’s suvorexant NDA for standard review

Merck, known as MSD outside the United States and Canada, today announced that the New Drug Application (NDA) for suvorexant, the company's investigational insomnia medicine, has been accepted for standard review by the U.S. Food and Drug Administration (FDA).

9 Nov 2012

UIC researchers develop transgenic Alzheimer's mouse with apoE4 gene

Researchers at the University of Illinois at Chicago College of Medicine have developed a transgenic mouse that carries a human gene known to increase risk of Alzheimer's 15-fold. This new mouse mimics the genetics of the human disease more closely than any of the dozen existing mouse models and may prove more useful in the development of candidate drugs to prevent or treat the disease.

9 Nov 2012

Lack of vitamin D2 associated with Alzheimer's

Scientists at London's Kingston University have uncovered evidence that lack of a particular form of vitamin D is associated with Alzheimer's disease.

8 Nov 2012

Plexxikon updates Zelboraf Phase 1 data on BRAF V600E mutation-positive melanoma

Plexxikon today announced that updated Phase 1 clinical data of Zelboraf (vemurafenib) were presented at the Society for Melanoma Research (SMR) 2012 Congress, held November 8-11 in Los Angeles, CA.

8 Nov 2012

Corneal limbal stromal cells could lead to new treatments for eye conditions

Eye experts and scientists at the University of Southampton have discovered specific cells in the eye which could lead to a new procedure to treat and cure blinding eye conditions.

8 Nov 2012

Low antioxidant levels contribute to increased blood pressure during exercise for people with PAD

Low antioxidant levels contribute to increased blood pressure during exercise for people with peripheral arterial disease, according to researchers at Penn State Hershey Heart and Vascular Institute.

8 Nov 2012

Pevion launches Defensomes platform for broad spectrum immune enhancement

Pevion Biotech AG today announced the launch of a new program called Defensomes, a platform for broad spectrum immune enhancement via mechanisms of innate immunity. The proprietary technology is derived from a vaccine platform with a solid safety track record comprising more than 80 million doses applied to humans to date. Defensomes offer opportunities for a wide range of prophylactic and therapeutic indications, where boosting of the body's own natural defense is beneficial.

8 Nov 2012

Patient recruitment complete for immatics IMA901 Phase 3 trial for renal cell carcinoma

immatics biotechnologies GmbH, a biopharmaceutical company developing rationally designed therapeutic vaccines that are active against cancer, announced today that it has completed patient recruitment into the pivotal phase 3 trial evaluating its lead cancer vaccine IMA901 for renal cell carcinoma (RCC). The trial has completed patient inclusion and it is expected that around 345 patients will be randomized across 10 countries in the US and Europe.

8 Nov 2012

FDA grants Albireo's A4250 orphan-drug designation for treatment of PFIC and PBC

Albireo AB, a biopharmaceutical company specializing in gastroenterology, today announced that A4250 (an inhibitor of the ileal bile acid transporter, IBAT/ASBT) has been granted orphan-drug designation by the U.S Food and Drug Administration for the treatment of Progressive Familial Intrahepatic Cholestasis (PFIC) and Primary Biliary Cirrhosis (PBC).

8 Nov 2012

Cardiac arrhythmias: an interview with Dr Andrew Grace

Cardiac arrhythmias are disturbances of the heartbeat. The heart can either go too slowly, which might make people collapse or exhausted; or too quickly.

8 Nov 2012

Study reveals increased risk of leukemia among Chernobyl cleanup workers

A 20-year study following 110,645 workers who helped clean up after the 1986 Chernobyl nuclear power plant accident in the former Soviet territory of Ukraine shows that the workers share a significant increased risk of developing leukemia. The results may help scientists better define cancer risk associated with low doses of radiation from medical diagnostic radiation procedures such as computed tomography scans and other sources.

8 Nov 2012

Better understanding of clotting dynamics in atherosclerosis could lead to more effective drugs

The disease atherosclerosis involves the build up of fatty tissue within arterial walls, creating unstable structures known as plaques. These plaques grow until they burst, rupturing the wall and causing the formation of a blood clot within the artery. These clots also grow until they block blood flow; in the case of the coronary artery, this can cause a heart attack.

8 Nov 2012

Study on genetic capacity of diverse populations to make critical PUFAs

World-renowned scientists are taking what they've learned from their multicenter research collaboration studying the health impact of fatty acids on diverse populations to set up a genetics center in India.

8 Nov 2012

Early clues regarding progression of Alzheimer's disease found in brain's metabolism

When it comes to Alzheimer's disease, scientists usually - and understandably - look to the brain as their first center of attention. Now researchers at Tel Aviv University say that early clues regarding the progression of the disease can be found in the brain's metabolism.

8 Nov 2012

Atherotech VAP Lipid Panel demonstrates accuracy in personalized heart disease risk assessment

Researchers using the Atherotech VAP Lipid Panel demonstrated the comprehensive lipid profile's accuracy in risk stratification through subclass measurement in two abstracts presented today at the American Heart Association (AHA) Scientific Sessions 2012.

8 Nov 2012

New understanding of how noise can break critical tip link protein structure in inner ear cells

Researchers have mapped the precise 3-D atomic structure of a thin protein filament critical for cells in the inner ear and calculated the force necessary to pull it apart.

8 Nov 2012

Autologous stem cells do not improve heart function when given three weeks after heart attack

Administering stem cells derived from patients' own bone marrow either three or seven days after a heart attack is safe but does not improve heart function six months later, according to a clinical trial supported by the National Institutes of Health (NIH).

8 Nov 2012

Landmark study could lead to fewer inappropriate shocks from implanted defibrillators

Loyola University Medical Center is among the centers participating in a landmark study that could lead to fewer inappropriate shocks from implanted defibrillators.

8 Nov 2012

PBS documentary explores stories and science behind organ donation and transplantation

Transplant: A Gift for Life -- a one-hour, Emmy Award-winning PBS documentary that includes Mayo Clinic transplant patients, their families, and doctors -- will be distributed to public television stations nationwide this month. On Nov. 8, more than 60 PBS stations will air the program simultaneously through the PBS World channel, and many other PBS stations will air the program at various times (check local listings) over the next three years.

8 Nov 2012

Medical Condition News

HCT 1026 may help stem debilitating effects of muscular dystrophy

FDA accepts Merck’s suvorexant NDA for standard review

UIC researchers develop transgenic Alzheimer's mouse with apoE4 gene

Lack of vitamin D2 associated with Alzheimer's

Plexxikon updates Zelboraf Phase 1 data on BRAF V600E mutation-positive melanoma

Corneal limbal stromal cells could lead to new treatments for eye conditions

Low antioxidant levels contribute to increased blood pressure during exercise for people with PAD

Pevion launches Defensomes platform for broad spectrum immune enhancement

Patient recruitment complete for immatics IMA901 Phase 3 trial for renal cell carcinoma

FDA grants Albireo's A4250 orphan-drug designation for treatment of PFIC and PBC

Cardiac arrhythmias: an interview with Dr Andrew Grace

Study reveals increased risk of leukemia among Chernobyl cleanup workers

Better understanding of clotting dynamics in atherosclerosis could lead to more effective drugs

Study on genetic capacity of diverse populations to make critical PUFAs

Early clues regarding progression of Alzheimer's disease found in brain's metabolism

Atherotech VAP Lipid Panel demonstrates accuracy in personalized heart disease risk assessment

New understanding of how noise can break critical tip link protein structure in inner ear cells

Autologous stem cells do not improve heart function when given three weeks after heart attack

Landmark study could lead to fewer inappropriate shocks from implanted defibrillators

PBS documentary explores stories and science behind organ donation and transplantation

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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