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Stapled Peptide oncology drug candidate exhibits robust efficacy in xenograft cancer models

Aileron Therapeutics, Inc. and its collaborator Roche today announced new results of a preclinical study of its Stapled Peptide oncology drug candidate ATSP-7041, which exhibited robust efficacy in MDM2 and MDMX xenograft cancer models.

8 Nov 2012

Most patients taking common blood-thinning drugs may be receiving wrong dosage levels

Cardiology researchers at the Intermountain Medical Center Heart Institute have found that approximately 75 percent of patients taking two common blood-thinning drugs may be receiving the wrong dosage levels, according to a new study.

8 Nov 2012

Sensory substitution devices provide visual information to the blind via existing senses

Common wisdom has it that if the visual cortex in the brain is deprived of visual information in early infanthood, it may never develop properly its functional specialization, making sight restoration later in life almost impossible.

8 Nov 2012

Reduce intensity of exercising when sick

Stuffy noses, hacking coughs and aches all over—cold and flu season has arrived. Though your body may be aching and your nose running like a faucet, it can be difficult to decide if you should continue your exercise routine or take a temporary break.

8 Nov 2012

Simple biomarker model to predict heart failure risk

The most widely used models for predicting heart failure rely on a complex combination of lifestyle, demographic, and cardiovascular risk factor information.

8 Nov 2012

Radiopharmaceutical Tektrotyd continues to receive interest and recognition

Physicians - attendees of the 25th Annual EANM (European Association of Nuclear Medicine) Congress (October 27-31, Milan) - expressed their continuing interest in and recognition for Tektrotyd, a radiopharmaceutical responsible for significant progress in diagnostics/therapy of neuroendocrine tumours.

8 Nov 2012

U-M to improve disease diagnosis through metabolic profiling

The University of Michigan Health System has earned a $9.1 million core grant from the National Institutes of Health to improve disease diagnosis through metabolic profiling.

8 Nov 2012

Women more likely to develop spice allergy

Imagine a world where you could never dine away from home, wear makeup, smell of sweet perfumes or eat a large percentage of food on store shelves. According to allergists at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting that is kicking off today in Anaheim, Calif., that is the world for 2 to 3 percent of individuals living with a spice allergy.

8 Nov 2012

Carbohydrate-rich food intake may cause recurrence of colon cancer

Colon cancer survivors whose diet is heavy in complex sugars and carbohydrate-rich foods are far more likely to have a recurrence of the disease than are patients who eat a better balance of foods, a new study by Dana-Farber Cancer Institute researchers indicates.

8 Nov 2012

Scientists develop measures to prevent health problems associated with biogenic amines in wine

Biogenic amines may be one of the factors responsible for symptoms such as headaches, gastro-intestinal disorders, shortness of breath, fall in blood pressure, and even unconsciousness and cardiac arrhythmia in severe cases. Histamine, one of the best known members of this group, can cause serious physical problems. Biogenic amines can be produced in the body by natural metabolic activities but are also ingested in larger quantities with food.

8 Nov 2012

Loyola plays an integral role in providing specialized training for future military physicians

Loyola University Chicago Stritch School of Medicine is playing an integral role in providing specialized training and support for medical students who are preparing to serve as physicians in the U.S. military.

8 Nov 2012

EUROECHO 2012 reveals how imaging improves early diagnosis of atherosclerosis

"Atherosclerosis is the leading cause of cardiovascular disease and the leading killer in Europe," said Professor Patrizio Lancellotti, President-Elect of the EACVI and Chairman of the EUROECHO Scientific Programme Committee. "Many of these deaths could be averted by diagnosis at a preclinical stage or early after the onset of symptoms."

8 Nov 2012

New UTSW model can predict progression of skin cancer in patients

UT Southwestern Medical Center scientists led by Dr. Sean Morrison, director of the Children's Medical Center Research Institute at UT Southwestern, have developed an innovative model for predicting the progression of skin cancer in patients.

8 Nov 2012

BMI may not be best measure for estimation of cancer risk

A study by researchers at Albert Einstein College of Medicine of Yeshiva University suggests that body mass index (BMI)-the most commonly used weight-for-height formula for estimating fatness-may not be the best measure for estimating disease risk, and particularly the risk of certain types of cancer. The study was published today in the online edition of the American Journal of Epidemiology.

8 Nov 2012

In silico drug design may lead to new approach in treatment of Alzheimer's

Researchers at Dalhousie University have discovered a new technique using "computer-aided" drug design that may lead to an entirely new approach in the treatment of Alzheimer's disease (AD).

8 Nov 2012

Metformin more effective than sulfonylurea in controlling type 2 diabetes

A Vanderbilt study examining the impact of the two most commonly prescribed oral diabetes medications on the risk for heart attack, stroke and death has found the drug metformin has benefits over sulfonylurea drugs.

8 Nov 2012

UC Irvine researchers create new stem cell-derived cell type for treatment of Alzheimer's

UC Irvine researchers have created a new stem cell-derived cell type with unique promise for treating neurodegenerative diseases such as Alzheimer's.

8 Nov 2012

Thyroid journal publishes new ATA guidelines for management of anaplastic thyroid cancer

Anaplastic thyroid cancer is a rare form of thyroid tumor, but it is also the most deadly. Newly developed evidence-based recommendations for the diagnosis, treatment, and long-term monitoring and follow-up care of patients with this extremely aggressive form of thyroid cancer are published in Thyroid, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

8 Nov 2012

Aspirin viable alternative to warfarin in preventing clots after joint replacement surgery

If you've had joint replacement surgery, it's likely you've been given warfarin, a common blood thinner and clot-preventer, prior to surgery. While effective, research from the Rothman Institute at Jefferson has shown aspirin to be just as effective in preventing clots, specifically pulmonary emboli, life-threatening blood clots that can develop in the arteries of the lungs following joint replacement surgery.

8 Nov 2012

Calcium intake does not increase risk of coronary artery calcification

Researchers at the Institute for Aging Research (IFAR) at Hebrew SeniorLife, an affiliate of Harvard Medical School (HMS), have published a study that shows no evidence of a link between calcium intake and coronary artery calcification, reassuring adults who take calcium supplements for bone health that the supplements do not appear to result in the development of calcification of blood vessels.

8 Nov 2012

Medical Condition News

Stapled Peptide oncology drug candidate exhibits robust efficacy in xenograft cancer models

Most patients taking common blood-thinning drugs may be receiving wrong dosage levels

Sensory substitution devices provide visual information to the blind via existing senses

Reduce intensity of exercising when sick

Simple biomarker model to predict heart failure risk

Radiopharmaceutical Tektrotyd continues to receive interest and recognition

U-M to improve disease diagnosis through metabolic profiling

Women more likely to develop spice allergy

Carbohydrate-rich food intake may cause recurrence of colon cancer

Scientists develop measures to prevent health problems associated with biogenic amines in wine

Loyola plays an integral role in providing specialized training for future military physicians

EUROECHO 2012 reveals how imaging improves early diagnosis of atherosclerosis

New UTSW model can predict progression of skin cancer in patients

BMI may not be best measure for estimation of cancer risk

In silico drug design may lead to new approach in treatment of Alzheimer's

Metformin more effective than sulfonylurea in controlling type 2 diabetes

UC Irvine researchers create new stem cell-derived cell type for treatment of Alzheimer's

Thyroid journal publishes new ATA guidelines for management of anaplastic thyroid cancer

Aspirin viable alternative to warfarin in preventing clots after joint replacement surgery

Calcium intake does not increase risk of coronary artery calcification

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