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Brown University biochemist targets diabetes

People with type 2 diabetes can make insulin but their bodies use it so poorly that glucose levels run amok. It's been difficult for scientists to understand what's going awry in the way that tiny, fast-moving proteins signal and regulate glucose metabolism. As a result, while drugs can help somewhat, many patients still must monitor their glucose and inject insulin.

10 Jan 2014

Undergraduate students develop innovative, non-X-ray device that evaluates spinal movement

Those have undergone extensive back surgery and need repeated X-rays to monitor their progress may soon have access to a new technology that skips the X-rays and repeated radiation exposure, opting instead for an innovative, noninvasive, non-X-ray device that evaluates spinal movement.

10 Jan 2014

Remission from depression is delayed in adults who experienced physical abuse in childhood

Remission from depression is delayed in adults who have experienced childhood physical abuse or parental addictions, a new study by University of Toronto researchers has found.

10 Jan 2014

Discovery opens new therapeutic avenue for chronic skin condition affecting millions

Researchers from the La Jolla Institute for Allergy and Immunology have revealed a critical player in the cellular interactions leading to eczema - a chronic inflammatory skin condition affecting more than 14 million U.S. children and adults.

10 Jan 2014

T2HemoStat detection of novel clot behavior could direct therapeutic choices for stroke, heart attack victims

T2 Biosystems, a company developing direct detection products enabling superior diagnostics, announced that scientists from the University of Pennsylvania and T2 Biosystems have published a paper in Blood describing novel clot structure biology detected while testing T2 Bio's T2HemoStat-.

10 Jan 2014

New study gives hope for novel glioblastoma multiforme treatment

A new study is giving researchers hope that novel targeted therapies can be developed for glioblastoma multiforme, the most common and most aggressive form of brain cancer, after demonstrating for the first time that a gene known as melanoma differentiation associated gene-9/syntenin (mda-9/syntenin) is a driving force behind the disease's aggressive and invasive nature.

9 Jan 2014

Study questions widely used method of diagnosing acute mountain sickness

A study led by University of British Columbia scientists calls into question a widely used method of diagnosing acute mountain sickness.

9 Jan 2014

Low doses of anticancer drug can prevent development of diabetes mellitus type 1

Very low doses of a drug used to treat certain types of cancer protect the insulin-producing cells in the pancreas and prevent the development of diabetes mellitus type 1 in mice. The medicine works by lowering the level of so-called sterile inflammation. The findings have been made by researchers from the University of Copenhagen, the Technical University of Denmark and the University of Southern Denmark working with researchers in Belgium, Italy, Canada, Netherlands and the USA.

9 Jan 2014

Antipsychotic medication can actively combat cells of difficult-to-treat form of ALL

In a prime example of finding new uses for older drugs, studies in zebrafish show that a 50-year-old antipsychotic medication called perphenazine can actively combat the cells of a difficult-to-treat form of acute lymphoblastic leukemia. The drug works by turning on a cancer-suppressing enzyme called PP2A and causing malignant tumor cells to self-destruct.

9 Jan 2014

TSRI researchers develop new fluid biopsy technique to identify patients at high risk of heart attack

A new "fluid biopsy" technique that could identify patients at high risk of a heart attack by identifying specific cells as markers in the bloodstream has been developed by a group of researchers at The Scripps Research Institute.

9 Jan 2014

New study compares blood pressure management in the US and England

In the US but not in England, patients on low incomes with high blood pressure have their condition managed poorly compared with those who earn more.

9 Jan 2014

Trevena doses first patient in TRV027 Phase 2b trial for acute heart failure

Trevena, Inc., a clinical stage pharmaceutical company involved in the discovery and development of G-protein coupled receptor biased ligands, announced today initiation of dosing in BLAST-AHF, the Company's randomized, multi-center Phase 2b trial of TRV027 in patients with acute heart failure.

9 Jan 2014

Biogen Idec, Sangamo BioSciences partner to develop therapeutics for hemoglobinopathies

Biogen Idec and Sangamo BioSciences, Inc. announced today an exclusive worldwide collaboration and license agreement focused on the development of therapeutics for hemoglobinopathies, inherited conditions that result from the abnormal structure or underproduction of hemoglobin.

9 Jan 2014

Nottingham scientists exploit MRI technology to assist in the treatment of IBS

Scientists at The University of Nottingham are leading the world in exploiting MRI technology to assist in the treatment and diagnosis of Irritable Bowel Syndrome, a condition that causes serious inconvenience and discomfort to sufferers.

9 Jan 2014

Full-service restaurant chains serve foods high in calories, fat

Food prepared away from home is typically higher in calories and lower in nutrition than food prepared at home, but it now makes up more than one-third of all calories purchased in the United States. Consumers tend to view full-service restaurants as providing healthier, higher quality food than fast-food restaurants, but some studies have found much higher calorie, fat, and sodium levels in food at full-service restaurants.

9 Jan 2014

High aerobic fitness in late adolescence may reduce heart attack risk later in life

Researchers in Sweden have found an association between a person’s fitness as a teenager and their risk of heart attack in later life. In a study of nearly 750,000 men, they found that the more aerobically fit men were in late adolescence, the less likely they were to have a heart attack 30 or 40 years later.

9 Jan 2014

Subset of TH17 cells linked to inflammation in Crohn’s disease patients, find TSRI scientists

Two-thirds to three-quarters of the estimated 700,000 Americans living with Crohn’s disease, an autoimmune condition that can disrupt the entire gastrointestinal tract, will require surgery at some point during their life. Patients and physicians often turn to this surgical intervention after a patient develops resistance to current treatments, such as steroids.

9 Jan 2014

Auxilium Pharmaceuticals reports interim data from XIAFLEX Phase 4 study in patients with DC

Auxilium Pharmaceuticals, Inc., a fully integrated specialty biopharmaceutical company, today announced that interim data from its Phase 4 retreatment study (AUX-CC-862) evaluating XIAFLEX (collagenase clostridium histolyticum or CCH) in adult patients with Dupuytren's contracture and a recurrent contracture with a palpable cord will be presented for the first time at the American Association for Hand Surgery 2014 Annual Meeting being held January 8-11, 2014 in Kauai, Hawaii.

9 Jan 2014

Immune tolerance to grafts of muscle, bone and skin could free recipients from lifelong immunosuppression

Massachusetts General Hospital investigators have made an important step towards greater availability of hand transplants, face transplants and other transplants involving multiple types of tissue.

9 Jan 2014

TSRI scientists identify small subset of immune cells that play major role in development of Crohn's disease

Two-thirds to three-quarters of the estimated 700,000 Americans living with Crohn's disease, an autoimmune condition that can disrupt the entire gastrointestinal tract, will require surgery at some point during their life.

9 Jan 2014

Medical Condition News

Brown University biochemist targets diabetes

Undergraduate students develop innovative, non-X-ray device that evaluates spinal movement

Remission from depression is delayed in adults who experienced physical abuse in childhood

Discovery opens new therapeutic avenue for chronic skin condition affecting millions

T2HemoStat detection of novel clot behavior could direct therapeutic choices for stroke, heart attack victims

New study gives hope for novel glioblastoma multiforme treatment

Study questions widely used method of diagnosing acute mountain sickness

Low doses of anticancer drug can prevent development of diabetes mellitus type 1

Antipsychotic medication can actively combat cells of difficult-to-treat form of ALL

TSRI researchers develop new fluid biopsy technique to identify patients at high risk of heart attack

New study compares blood pressure management in the US and England

Trevena doses first patient in TRV027 Phase 2b trial for acute heart failure

Biogen Idec, Sangamo BioSciences partner to develop therapeutics for hemoglobinopathies

Nottingham scientists exploit MRI technology to assist in the treatment of IBS

Full-service restaurant chains serve foods high in calories, fat

High aerobic fitness in late adolescence may reduce heart attack risk later in life

Subset of TH17 cells linked to inflammation in Crohn’s disease patients, find TSRI scientists

Auxilium Pharmaceuticals reports interim data from XIAFLEX Phase 4 study in patients with DC

Immune tolerance to grafts of muscle, bone and skin could free recipients from lifelong immunosuppression

TSRI scientists identify small subset of immune cells that play major role in development of Crohn's disease

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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