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People with severe mental illness may have higher risk for substance use

People with severe mental illness such as schizophrenia or bipolar disorder have a higher risk for substance use, especially cigarette smoking, and protective factors usually associated with lower rates of substance use do not exist in severe mental illness, according to a new study funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.

5 Jan 2014

Parkinson's disease patients from lower socioeconomic status less likely to receive DBS

Among Parkinson's disease (PD) patients, female, black, Asian and patients are substantially less likely to receive proven deep brain stimulation (DBS) surgery to improve tremors and motor symptoms, according to a new report by a Perelman School of Medicine at the University of Pennsylvania researcher who identified considerable disparities among Medicare recipients receiving DBS for Parkinson's disease.

5 Jan 2014

Researchers develop new tool that accurately predicts individual's risk of colorectal cancer

Researchers at Cleveland Clinic have developed a new tool called CRC-PRO that allows physicians to quickly and accurately predict an individual's risk of colorectal cancer, as published in the current edition of the Journal of the American Board of Family Medicine.

5 Jan 2014

Study shows endoplasmic reticulum stress plays important role in diabetic retinopathy

Endoplasmic reticulum stress is closely involved in the early stage of diabetic retinopathy. According a study published in the Neural Regeneration Research (Vol. 8, No. 33, 2013), endoplasmic reticulum stress played an important role in the hyperglycemia-induced death of ganglion cells and impairment of retinal microvessels.

5 Jan 2014

Dysfunction in MADD gene in mice causes fasting hyperglycemia

Researchers from the University of Illinois at Chicago College of Medicine have found that dysfunction in a single gene in mice causes fasting hyperglycemia, one of the major symptoms of type 2 diabetes. Their findings were reported online in the journal Diabetes.

5 Jan 2014

RegeneRx's Tβ4 gets FDA Orphan Drug designation for treatment of Neurotrophic Keratopathy

RegeneRx Biopharmaceuticals, Inc. announced that it has received Orphan Drug designation from U.S. FDA's Office of Orphan Products Development for its drug candidate, Thymosin beta 4 (Tβ4), for the treatment of Neurotrophic Keratopathy, a serious degenerative disease of the corneal epithelium (the outside layer of the eye).

5 Jan 2014

NPS Pharmaceuticals' Natpara gets orphan drug designation for treatment of hypoparathyroidism

NPS Pharmaceuticals, Inc., a global biopharmaceutical company pioneering and delivering therapies that transform the lives of patients with rare diseases, today announced that the European Commission has granted orphan drug designation to Natpara (recombinant human parathyroid hormone (rhPTH[1-84]) for the treatment of hypoparathyroidism.

3 Jan 2014

Marina Biotech, Mirna modify license agreement regarding development of microRNA-based therapeutics

Marina Biotech, Inc., a leading oligonucleotide-based drug discovery and development company, and Mirna Therapeutics, Inc., a privately-held biotechnology company pioneering microRNA replacement therapy for cancer, announced today that they have amended their license agreement regarding the development and commercialization of microRNA-based therapeutics utilizing Mirna's proprietary microRNAs and Marina Biotech's novel SMARTICLES liposomal delivery technology.

3 Jan 2014

Fear of childbirth puts women at higher risk of postpartum depression

Expectant women with prenatally diagnosed fear of childbirth are at an increased risk of postpartum depression, according to a study of over 500,000 mothers in Finland. Women with a history of depression are at the highest risk of postpartum depression.

3 Jan 2014

AstraZeneca to take over Probiodrug's CDK9 inhibitor program

Probiodrug AG announced today the transfer of its experimental cyclin-dependent kinase 9 inhibitor program to AstraZeneca. The transaction includes the sale to AstraZeneca of a lead molecule and back-up compounds with the associated intellectual property. CDK9, which has been implicated in the transcriptional regulation of genes involved in proliferation and inflammation, is a promising target for the treatment of both cancer and inflammatory diseases.

3 Jan 2014

Women In Government announces launch of Pulmonary Hypertension Legislative Toolkit

Women In Government today announced the launch of its Pulmonary Hypertension Legislative Toolkit, designed to provide information and resources regarding Pulmonary Hypertension for women state legislators.

3 Jan 2014

iRhythm Technologies’ ZIO Service detects more cardiac arrhythmias than Holter monitor

iRhythm Technologies, a healthcare information services company, today announced that a prospective study by Scripps Translational Science Institute (STSI) has found that use of the company's ZIO Service significantly increased detection of cardiac arrhythmias, compared to use of the traditional Holter monitor.

3 Jan 2014

Novel technique helps people with word blindness to read again

In the journal Neurology, researchers report a novel technique that enables a patient with "word blindness" to read again.

3 Jan 2014

NPSP to conduct open-label study to evaluate teduglutide in pediatric patients with SBS

NPS Pharmaceuticals, Inc. (NASDAQ: NPSP), a global biopharmaceutical company pioneering and delivering therapies that transform the lives of patients with rare diseases worldwide, today announced that the company has initiated a global registration study of teduglutide in pediatric patients with Short Bowel Syndrome (SBS) who are dependent on parenteral support.

3 Jan 2014

STSI researchers develop a small wireless device that detects abnormal, dangerous heart rhythms

Research by the Scripps Translational Science Institute (STSI) has found that a small adhesive wireless device worn on the chest for up to two weeks does a better job detecting abnormal and potentially dangerous heart rhythms than the Holter monitor, which is typically used for 24 hours and has been the standard of care for more than 50 years.

3 Jan 2014

Kessler conducts research study to improve health and quality of life of military personnel with SCI

Kessler Foundation is conducting a 3-year research study to improve the health and quality of life of military personnel and civilians with spinal cord injury (SCI). The study, 'Systematic Assessment of Caregiving Skill Performance by Individuals with Tetraplegia and their Caregivers', is funded by a $590,540 grant from a special program in the Department of Defense (W81XWH-12-1-0553).

3 Jan 2014

Overweight minority women less aware of the increased risk of cardiovascular disease

Minority women tend to be less aware of the increased risk of cardiovascular disease they face by being overweight or obese. The results of a study that compared Hispanic and non-Hispanic white women based on their knowledge of heart disease risk factors and their perceptions of their own weight is published in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

3 Jan 2014

Study suggests that ROR1 could be an important therapeutic target for patients with CLL

Researchers at the University of California, San Diego School of Medicine report that an oncogene dubbed ROR1, found on chronic lymphocytic leukemia (CLL) B cells but not normal adult tissues, acts as an accelerant when combined with another oncogene, resulting in a faster-developing, more aggressive form of CLL in mice.

3 Jan 2014

Chinese herbal medicine effective at alleviating acute inflammatory and nerve pain

A compound derived from a traditional Chinese herbal medicine has been found effective at alleviating pain, pointing the way to a new nonaddictive analgesic for acute inflammatory and nerve pain, according to UC Irvine pharmacology researchers.

3 Jan 2014

Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance, hyperalgesia

Currently, opioids are the standard treatment for chronic pain. Patients on opioids for long periods of time become desensitized to these drugs or become paradoxically hypersensitive to pain (hyperalgesia); however, the adaptive mechanisms are not well understood.

3 Jan 2014

Medical Condition News

People with severe mental illness may have higher risk for substance use

Parkinson's disease patients from lower socioeconomic status less likely to receive DBS

Researchers develop new tool that accurately predicts individual's risk of colorectal cancer

Study shows endoplasmic reticulum stress plays important role in diabetic retinopathy

Dysfunction in MADD gene in mice causes fasting hyperglycemia

RegeneRx's Tβ4 gets FDA Orphan Drug designation for treatment of Neurotrophic Keratopathy

NPS Pharmaceuticals' Natpara gets orphan drug designation for treatment of hypoparathyroidism

Marina Biotech, Mirna modify license agreement regarding development of microRNA-based therapeutics

Fear of childbirth puts women at higher risk of postpartum depression

AstraZeneca to take over Probiodrug's CDK9 inhibitor program

Women In Government announces launch of Pulmonary Hypertension Legislative Toolkit

iRhythm Technologies’ ZIO Service detects more cardiac arrhythmias than Holter monitor

Novel technique helps people with word blindness to read again

NPSP to conduct open-label study to evaluate teduglutide in pediatric patients with SBS

STSI researchers develop a small wireless device that detects abnormal, dangerous heart rhythms

Kessler conducts research study to improve health and quality of life of military personnel with SCI

Overweight minority women less aware of the increased risk of cardiovascular disease

Study suggests that ROR1 could be an important therapeutic target for patients with CLL

Chinese herbal medicine effective at alleviating acute inflammatory and nerve pain

Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance, hyperalgesia

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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