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Oncolytics completes patient enrollment in phase II metastatic pancreatic cancer study

Oncolytics Biotech Inc. today announced completion of patient enrollment in a two-arm randomized phase II study of carboplatin, paclitaxel plus REOLYSIN versus carboplatin and paclitaxel alone in the first line treatment of patients with recurrent or metastatic pancreatic cancer (OSU-10045).

8 Jul 2014

CSI and Fabien Cousteau's Mission 31 examine impact of sleep in individuals living underwater

United States Navy and NASA researchers have each examined the impact of sleep in individuals living and working underwater but researchers with Clayton Sleep Institute (CSI) in St. Louis are hoping to gain new insight with a study in cooperation with Fabien Cousteau's Mission 31.

8 Jul 2014

Hypertension does not respond to therapy due to inadequate diagnosis

High blood pressure—also known as hypertension—is widespread, but treatment often fails. One in five people with hypertension does not respond to therapy. This is frequently due to inadequate diagnosis, as Franz Weber and Manfred Anlauf point out in the current issue of Deutsches Ärzteblatt International.

8 Jul 2014

Caregivers of cancer patients can manage end-of-life treatment, decisions with help from support team

Many caregivers of terminal cancer patients suffer depression and report regret and guilt from feeling they could have done more to eliminate side effects and relieve the pain.

8 Jul 2014

Pseudogenes may play key role in the discovery of new biomarkers

Dysfunctional, unloved and seemingly of little use, these poor-cousin relatives of genes have lost their protein-coding abilities. They contain material not essential for an organism's survival and are the "last stop" for removal of genomic waste.

8 Jul 2014

New mechanism of chemotherapy resistance in triple-negative inflammatory breast cancer

Researchers at Roswell Park Cancer Institute (RPCI) have identified a mechanism of breast cancer cells that leads to chemotherapy resistance in inflammatory breast cancer.

8 Jul 2014

Study: Behavioral weight loss can help manage menopausal hot flashes

Now women have yet one more incentive to lose weight as a new study has shown evidence that behavioral weight loss can help manage menopausal hot flashes.

8 Jul 2014

Insights into how cells move could lead to innovative techniques to stop spread of cancer

Insights into how cells move through the body could lead to innovative techniques to stop cancer cells from spreading and causing secondary tumours, according to new UCL research.

8 Jul 2014

CWRU receives $12.6 million from NIA to identify rare genetic variants that contribute to Alzheimer's

Researchers from Case Western Reserve University School of Medicine are part of a five-university collaboration receiving a $12.6 million, four-year grant from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), to identify rare genetic variants that may either protect against, or contribute to Alzheimer's disease risk.

8 Jul 2014

Study provides new knowledge about EphA2 receptor involved in several forms of cancer

Researchers at Karolinska Institutet in Sweden have headed a study that provides new knowledge about the EphA2 receptor, which is significant in several forms of cancer. This is important knowledge in itself - but just as important is how this study, which is published in the highly respected journal Nature Methods, was conducted.

8 Jul 2014

ASN Foundation for Kidney Research provides $2.8 million to improve care for kidney patients

The American Society of Nephrology and the ASN Foundation for Kidney Research will fund $2.8 million in original, meritorious research in 2014 to improve care for the more than 20 million Americans with kidney disease, and for kidney patients worldwide.

8 Jul 2014

Excessive belly fat: A risk factor for chronic obstructive pulmonary disease

Obesity, especially excessive belly fat, is a risk factor for chronic obstructive pulmonary disease (COPD), according to an article in CMAJ (Canadian Medical Association Journal).

7 Jul 2014

Sleep deprivation can lead a healthy person to display symptoms similar to schizophrenia

Twenty-four hours of sleep deprivation can lead to conditions in healthy persons similar to the symptoms of schizophrenia. This discovery was made by an international team of researchers under the guidance of the University of Bonn and King's College London.

7 Jul 2014

CASI's ENMD-2076 gets FDA Orphan Drug designation for HCC treatment

CASI Pharmaceuticals, Inc., a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and other diseases, announced today that its orally-active, Aurora A/angiogenic kinase inhibitor, ENMD-2076, has received Orphan Drug designation from the U.S. Food and Drug Administration for the treatment of hepatocellular carcinoma (HCC).

7 Jul 2014

$FDA grants Breakthrough Therapy status to Novartis' CTL019 for treatment of relapsed/refractory ALL$

FDA grants Breakthrough Therapy status to Novartis' CTL019 for treatment of relapsed/refractory ALL

Novartis announced today that the United States Food and Drug Administration has granted Breakthrough Therapy status to CTL019, an investigational chimeric antigen receptor (CAR) therapy for the treatment of pediatric and adult patients with relapsed/refractory acute lymphoblastic leukemia (r/r ALL).

7 Jul 2014

Penn’s immunotherapy receives FDA's Breakthrough Therapy designation for ALL treatment

A University of Pennsylvania-developed personalized immunotherapy has been awarded the U.S. Food and Drug Administration's Breakthrough Therapy designation for the treatment of relapsed and refractory adult and pediatric acute lymphoblastic leukemia (ALL).

7 Jul 2014

Bayer announces Health Canada approval of Nexavar for differentiated thyroid cancer treatment

Bayer Inc. is pleased to announce the Health Canada approval of Nexavar for the treatment of patients with locally advanced or metastatic, progressive, differentiated thyroid carcinoma (DTC), refractory to radioactive iodine (RAI).

7 Jul 2014

Investigators report effects of internet based treatment on obsessive symptoms

A group of German investigators reports on the affects of internet based treatment on obsessive symptoms in the current issue of Psychotherapy and Psychosomatics.

7 Jul 2014

Treating ulcerative colitis and Crohn’s disease

Ulcerative colitis and Crohn’s disease are idiopathic (we don’t know the cause) inflammatory diseases (IBD) of the colon and/or small bowel. They are chronic in that we do not have a medical cure and are differentiated from IBS (irritable bowel syndrome) by inflammation that causes ulcerations of the GI tract.

7 Jul 2014

Grunenthal Group submits Marketing Authorization Application to EMA for ZALVISO

AcelRx Pharmaceuticals, Inc. and Grunenthal Group announced today that Grunenthal has submitted a Marketing Authorization Application (MAA) to the European Medicines Authority for ZALVISO for the management of moderate to severe acute pain in adult patients in a medically supervised environment.

7 Jul 2014

Medical Condition News

Oncolytics completes patient enrollment in phase II metastatic pancreatic cancer study

CSI and Fabien Cousteau's Mission 31 examine impact of sleep in individuals living underwater

Hypertension does not respond to therapy due to inadequate diagnosis

Caregivers of cancer patients can manage end-of-life treatment, decisions with help from support team

Pseudogenes may play key role in the discovery of new biomarkers

New mechanism of chemotherapy resistance in triple-negative inflammatory breast cancer

Study: Behavioral weight loss can help manage menopausal hot flashes

Insights into how cells move could lead to innovative techniques to stop spread of cancer

CWRU receives $12.6 million from NIA to identify rare genetic variants that contribute to Alzheimer's

Study provides new knowledge about EphA2 receptor involved in several forms of cancer

ASN Foundation for Kidney Research provides $2.8 million to improve care for kidney patients

Excessive belly fat: A risk factor for chronic obstructive pulmonary disease

Sleep deprivation can lead a healthy person to display symptoms similar to schizophrenia

CASI's ENMD-2076 gets FDA Orphan Drug designation for HCC treatment

FDA grants Breakthrough Therapy status to Novartis' CTL019 for treatment of relapsed/refractory ALL

Penn’s immunotherapy receives FDA's Breakthrough Therapy designation for ALL treatment

Bayer announces Health Canada approval of Nexavar for differentiated thyroid cancer treatment

Investigators report effects of internet based treatment on obsessive symptoms

Treating ulcerative colitis and Crohn’s disease

Grunenthal Group submits Marketing Authorization Application to EMA for ZALVISO

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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