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Study suggests that ROR1 could be an important therapeutic target for patients with CLL

Researchers at the University of California, San Diego School of Medicine report that an oncogene dubbed ROR1, found on chronic lymphocytic leukemia (CLL) B cells but not normal adult tissues, acts as an accelerant when combined with another oncogene, resulting in a faster-developing, more aggressive form of CLL in mice.

3 Jan 2014

Chinese herbal medicine effective at alleviating acute inflammatory and nerve pain

A compound derived from a traditional Chinese herbal medicine has been found effective at alleviating pain, pointing the way to a new nonaddictive analgesic for acute inflammatory and nerve pain, according to UC Irvine pharmacology researchers.

3 Jan 2014

Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance, hyperalgesia

Currently, opioids are the standard treatment for chronic pain. Patients on opioids for long periods of time become desensitized to these drugs or become paradoxically hypersensitive to pain (hyperalgesia); however, the adaptive mechanisms are not well understood.

3 Jan 2014

University of Utah discovers cellular mechanism that stops metastasis of breast cancer

Researchers from Huntsman Cancer Institute (HCI) at the University of Utah discovered a cellular mechanism that drives the spread of breast cancer to other parts of the body (metastasis), as well as a therapy which blocks that mechanism. The research results were published online in the journal Cell Reports on January 2.

3 Jan 2014

City of Hope to offer radiation oncology services to patients in the Arcadia area

City of Hope and Methodist Hospital of Southern California have reached an agreement in which City of Hope will acquire the hospital's radiation oncology service in Arcadia. The acquisition will expand access to City of Hope's renowned expertise in radiation therapy and will provide additional convenience for patients seeking specialized cancer services.

2 Jan 2014

HealthAlliance of the Hudson Valley launches autism-friendly program for ASD patients

HealthAlliance of the Hudson Valley's Broadway Campus Emergency Department is launching a dynamic new program to provide an "autism-friendly" experience for patients with Autism Spectrum Disorder. With autism affecting 1 in 88 children, according to Autism Speaks, the commitment to addressing the specialized needs of Emergency Department patients with ASD is timely.

2 Jan 2014

Macrophages invade diabetic pancreatic tissue during early stages of type 2 diabetes

As people's waistlines increase, so does the incidence of type 2 diabetes. Now scientists have a better understanding of exactly what happens in the body that leads up to type 2 diabetes, and what likely causes some of the complications related to the disease. Specifically, scientists from Denmark have found that in mice, macrophages, a specific type of immune cell, invade the diabetic pancreatic tissue during the early stages of the disease.

2 Jan 2014

Nipro Diagnostics begins voluntary recall of TRUEbalance and TRUEtrack Blood Glucose Meters

Nipro Diagnostics, Inc. today announced it is initiating a voluntary recall and replacement of a limited number of TRUEbalance and TRUEtrack Blood Glucose Meters distributed both in the United States and outside the United States.

2 Jan 2014

New research shows that as we age, the thermogenic activity of brown fat gets reduced

As most people resolve themselves to lose weight this New Year, here's why it seems to get easier and easier to pack on unwanted pounds: New research published in the January 2014 issue of The FASEB Journal, shows that as we age, the thermogenic activity of brown fat is reduced. Brown fat is a "good" fat located in the backs of our necks that helps burn "bad" white fat around our bellies. Additionally, the researchers also discovered a possible metabolic on/off switch that could reactivate brown fat.

2 Jan 2014

Shingles may increase risk of stroke in later life, study finds

Having shingles may increase the risk of having a stroke years later, according to research published in the January 2, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

2 Jan 2014

Study finds only small therapeutic effect of CBT on schizophrenic symptoms

Health organisations around the world recommend a form of psychotherapy, known as cognitive-behavioural therapy or CBT, for patients with schizophrenia. Now, however, the most extensive study ever undertaken into its effect on the symptoms of the disorder finds little impact, according to a team of international researchers.

2 Jan 2014

Cerenis' Phase IIb CHI-SQUARE study fails to meet primary endpoint in post-ACS patients

Cerenis Therapeutics, the biopharmaceutical company, today announced that its Phase IIb CHI-SQUARE (Can HDL Infusions Significantly Quicken Atherosclerosis REgression?) study did not reach its primary endpoint in post-Acute Coronary Syndrome patients.

2 Jan 2014

TAVI is an effective alternative to AVR for treating aortic stenosis in very elderly patients

Transcatheter aortic valve implantation (TAVI) appears to be an effective alternative to surgical aortic valve replacement (AVR) for the treatment of aortic stenosis in very elderly patients, including those age 85 years and older, according to a study in the January 2014 issue of The Annals of Thoracic Surgery.

2 Jan 2014

Surgeon highlights factors that can prevent revision surgery after hip or knee replacement

Hundreds of thousands of hip and knee replacement surgeries are performed in the United States each year, and they are highly successful in eliminating pain, restoring mobility and improving quality of life.

2 Jan 2014

Research confirms superior antitumor activity of novel anticancer agent FL118

A team led by Fengzhi Li, PhD, of Roswell Park Cancer Institute has reported significant new findings regarding the chemical structure of the novel anticancer agent FL118. The research, which included comparative analysis of the agent and several similar compounds, confirms the broad, superior antitumor activity of FL118 and suggests promising directions for further studies.

2 Jan 2014

Amgen announces romosozumab Phase 2 trial results in postmenopausal women with low BMD

Amgen and UCB (Euronext Brussels:UCB) today announced results from a Phase 2 trial evaluating romosozumab (AMG 785/CDP7851) in postmenopausal women with low bone mineral density (BMD).

2 Jan 2014

Study reveals potential links to the underlying causes of cancers

New research by scientists at the University of Exeter has shown that cells demonstrate remarkable flexibility and versatility when it comes to how they divide - a finding with potential links to the underlying causes of many cancers.

2 Jan 2014

New tool may help predict retinal detachment after open globe injuries

Ocular trauma causing open globe injury, or a breach in the wall of the eye, remains an important cause of vision loss, with more than 200,000 open globe injuries occurring worldwide each year. In many cases, retinal detachment follows the traumatic injury, causing significant vision loss or blindness.

2 Jan 2014

Women with high blood pressure need more optimal treatment than men

Doctors may need to treat high blood pressure in women earlier and more aggressively than they do in men, according to scientists at Wake Forest Baptist Medical Center.

2 Jan 2014

FDA removes partial clinical hold on Cell Therapeutics' Tosedostat aminopeptidase inhibitor

Cell Therapeutics, Inc. (CTI) today announced that it has received notification from the U.S. Food and Drug Administration (FDA) that the partial clinical hold on tosedostat (IND 075503) has been removed and all studies underway may continue.

2 Jan 2014

Medical Condition News

Study suggests that ROR1 could be an important therapeutic target for patients with CLL

Chinese herbal medicine effective at alleviating acute inflammatory and nerve pain

Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance, hyperalgesia

University of Utah discovers cellular mechanism that stops metastasis of breast cancer

City of Hope to offer radiation oncology services to patients in the Arcadia area

HealthAlliance of the Hudson Valley launches autism-friendly program for ASD patients

Macrophages invade diabetic pancreatic tissue during early stages of type 2 diabetes

Nipro Diagnostics begins voluntary recall of TRUEbalance and TRUEtrack Blood Glucose Meters

New research shows that as we age, the thermogenic activity of brown fat gets reduced

Shingles may increase risk of stroke in later life, study finds

Study finds only small therapeutic effect of CBT on schizophrenic symptoms

Cerenis' Phase IIb CHI-SQUARE study fails to meet primary endpoint in post-ACS patients

TAVI is an effective alternative to AVR for treating aortic stenosis in very elderly patients

Surgeon highlights factors that can prevent revision surgery after hip or knee replacement

Research confirms superior antitumor activity of novel anticancer agent FL118

Amgen announces romosozumab Phase 2 trial results in postmenopausal women with low BMD

Study reveals potential links to the underlying causes of cancers

New tool may help predict retinal detachment after open globe injuries

Women with high blood pressure need more optimal treatment than men

FDA removes partial clinical hold on Cell Therapeutics' Tosedostat aminopeptidase inhibitor

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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