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Researchers decipher how AP-1 gene regulator controls survival of liver tumor-initiating cells

Researchers headed by Erwin Wagner, the Director of the BBVA Foundation-CNIO Cancer Cell Biology Programme at the Spanish National Cancer Research Centre (CNIO), have deciphered how a stress-inducible gene regulator, AP-1, controls the survival of liver tumor-initiating cells. These results, published in the online edition of Nature Cell Biology, could provide new preventive strategies and identify potentially targetable molecules to prevent liver cancer.

8 Oct 2012

Progenra’s USP7 and USP47 exert non-overlapping anticancer cell effects

Researchers at Progenra, Inc. announce the advanced online publication of the article "Selective Dual Inhibitors of the Cancer-related Deubiquitylating Proteases USP7 and USP47." The new article presents evidence of a therapeutic benefit resulting from dual inhibition of USP7 and a related enzyme, USP47.

8 Oct 2012

Kaneka to launch new Protein A Chromatography Resin for purification of therapeutic antibodies

Kaneka Corporation on 19/09/2012, announces the launch of KANEKA KanCapA, a new Protein A Chromatography Resin for the purification of therapeutic antibodies.

8 Oct 2012

Children with autism four times more likely to wander

A new study published today in the journal Pediatrics found that nearly half of children with autism spectrum disorders (ASD) are reported to wander or "bolt," and more than half of these children go missing.

8 Oct 2012

Incidence of needlestick injuries appears to be lower among employees at retail pharmacy chain

Vaccinations for flu, tetanus and other common vaccines are increasingly taking place in non-medical settings such as supermarkets and drug stores. This added responsibility for pharmacists increases the risk of needlestick injuries (NSIs), puncture wounds often suffered while preparing or after use of a needle. NSIs can transmit bloodborne pathogens, including hepatitis C and HIV, from an infected patient to the person administering the vaccine.

8 Oct 2012

New insight into basis of opiate addiction

Chronic morphine exposure has the opposite effect on the brain compared to cocaine in mice, providing new insight into the basis of opiate addiction, according to Mount Sinai School of Medicine researchers.

8 Oct 2012

New ways of how biological clock's neurons use electrical activity to keep behavioral rhythms in order

Biologists from New York University have uncovered new ways our biological clock's neurons use electrical activity to help keep behavioral rhythms in order. The findings, which appear in the journal Current Biology, also point to fresh directions for exploring sleep disorders and related afflictions.

6 Oct 2012

Researchers perfect map of vision in the brain based upon brain structure

Nearly 100 years after a British neurologist first mapped the blind spots caused by missile wounds to the brains of soldiers, Perelman School of Medicine researchers at the University of Pennsylvania have perfected his map using modern-day technology. Their results create a map of vision in the brain based upon an individual's brain structure, even for people who cannot see.

6 Oct 2012

People with lower socioeconomic status remain at higher risk of dying from colon cancer

Despite medical advances in colon cancer screening and treatment, people with a lower socioeconomic status remain at a higher risk of dying from colon cancer. A new study in The Milbank Quarterly finds that states and communities that focus on increasing the adoption of innovative health care practices along with providing greater access to public health information can reduce these deaths.

6 Oct 2012

HHS honors Children's Hospital Los Angeles for excellence in organ donation

The U.S. Department of Health and Human Services (HHS) is honoring Children's Hospital Los Angeles for its commitment to saving lives through organ and tissue donation. The hospital will receive the Silver Medal of Honor today for excellence in organ donation at the 7th National Learning Congress for the Donation and Transplantation Community of Practice in Grapevine, Tex.

6 Oct 2012

Researchers identify mechanism that protects from developing uncontrollable fear

Researchers from the University of Exeter Medical School have for the first time identified the mechanism that protects us from developing uncontrollable fear.

6 Oct 2012

Department of Veterans Affairs implements pilot version of Diabetes Prevention Program

The Department of Veterans Affairs today announced the implementation of a pilot version of the Diabetes Prevention Program (DPP), a program being promoted nationally by the Centers for Disease Control and Prevention, aimed at reducing the number of Veterans who develop diabetes.

6 Oct 2012

Gene-silencing mechanism may occur later in life and lead to cancer

There are some genes that are only activated in the very first days of an embryo's existence. Once they have accomplished their task, they are shut down forever, unlike most of our genes, which remain active throughout our lives. EPFL scientists have unveiled part of this strange mechanism. The same process, accidentally initiated later in life, could be responsible for many kinds of cancer.

6 Oct 2012

Without B-Raf and C-Raf proteins mice's fur turns white

These proteins are required for melanocyte stem cell self-maintenance and, as such, correct pigmentation throughout the mice's life span. Without these two proteins, the mice's fur turns white. Their research is published in the review 'Cell Report' and paves the way for serious possibilities in terms of stopping the formation of melanomas, tumours that originate from melanocyte cells.

6 Oct 2012

NIH awards $2.1M grant to study possible ways to fight cancer

A professor with the University of Houston Cullen College of Engineering has won a $2.1 million grant to study the best ways to modify human immune cells to fight against cancer.

6 Oct 2012

Rember revamped for Phase 3 testing in behavioral-variant frontotemporal dementia

Rember—the blue dye that created a stir in 2008 when Phase 2 clinical trial data claimed that it slowed decline in people with Alzheimer's disease—has now been revamped for Phase 3 testing in another disease, behavioral-variant frontotemporal dementia (bvFTD).

6 Oct 2012

Researchers from three trials join to collaborate under European Dementia Prevention Initiative

Worldwide, the number of people with Alzheimer's disease will hit 115 million by 2050, according to the World Health Organization. Scientists, health officials, policymakers, and the public are asking if anything can slow down the disease.

6 Oct 2012

BUSM leads genome-wide evaluation of genetic variants associated with Parkinson's disease

Boston University School of Medicine investigators have led the first genome-wide evaluation of genetic variants associated with Parkinson's disease (PD). The study, which is published online in PLOS ONE, points to the involvement of specific genes and alterations in their expression as influencing the risk for developing PD.

6 Oct 2012

Benzodiazepine exposure for over-65s linked to increased risk of dementia

The results from comparative analysis of this population demonstrate the risk of developing dementia increased by 50% for subjects who consumed benzodiazepines during the follow-up period, compared with those who had never used benzodiazepines.

6 Oct 2012

Researchers discover brain mechanism responsible for sensation of nausea

Nausea is a common and distressing side effect of many drugs and treatments. Unlike vomiting, nausea is not well understood, but new research by University of Guelph scientists may soon change that.

6 Oct 2012

Medical Condition News

Researchers decipher how AP-1 gene regulator controls survival of liver tumor-initiating cells

Progenra’s USP7 and USP47 exert non-overlapping anticancer cell effects

Kaneka to launch new Protein A Chromatography Resin for purification of therapeutic antibodies

Children with autism four times more likely to wander

Incidence of needlestick injuries appears to be lower among employees at retail pharmacy chain

New insight into basis of opiate addiction

New ways of how biological clock's neurons use electrical activity to keep behavioral rhythms in order

Researchers perfect map of vision in the brain based upon brain structure

People with lower socioeconomic status remain at higher risk of dying from colon cancer

HHS honors Children's Hospital Los Angeles for excellence in organ donation

Researchers identify mechanism that protects from developing uncontrollable fear

Department of Veterans Affairs implements pilot version of Diabetes Prevention Program

Gene-silencing mechanism may occur later in life and lead to cancer

Without B-Raf and C-Raf proteins mice's fur turns white

NIH awards $2.1M grant to study possible ways to fight cancer

Rember revamped for Phase 3 testing in behavioral-variant frontotemporal dementia

Researchers from three trials join to collaborate under European Dementia Prevention Initiative

BUSM leads genome-wide evaluation of genetic variants associated with Parkinson's disease

Benzodiazepine exposure for over-65s linked to increased risk of dementia

Researchers discover brain mechanism responsible for sensation of nausea

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

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