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Researchers refute avalanche theory on cancer

First, the number of chromosomes in a cell changes, then an avalanche of further mutations occur that transform the cell into a cancer cell, according to a well-known - but untested - theory.

12 Dec 2013

New guidelines to manage heart failure in children

Heart failure in children is an important cause of childhood health problems and death. The Children's Heart Failure Study Group of the Canadian Cardiovascular Society, in collaboration with the Canadian Pediatric Cardiology Association, has developed new guidelines to assist practitioners in primary care and emergency departments to recognize and successfully manage heart failure in children with undiagnosed heart disease and symptoms of possible heart failure.

12 Dec 2013

Dementia much higher among Native Americans and African-Americans

In the first study to look at racial and ethnic differences in dementia risk among older adults with type 2 diabetes, researchers found that dementia was much higher among Native Americans and African-Americans and lowest among Asian-Americans.

12 Dec 2013

Immunocellular Therapeutics reports positive results from ICT-107 Phase II study in glioblastoma patients

ImmunoCellular Therapeutics, Ltd. ("ImmunoCellular") announced that ICT-107, its dendritic cell-based vaccine, demonstrated a statistically significant increase in progression-free survival (PFS) in patients with newly diagnosed glioblastoma multiforme (GBM) in its randomized, placebo-controlled phase II trial.

12 Dec 2013

Queen's University to lead €6 million European study to find new treatments for bowel cancer

Queen's University has announced it is to lead a -6 million European study to find new treatments for bowel cancer.

12 Dec 2013

New mechanism explains why anti-tumor activity of specific immune suppressed during tumor growth

The Leuven-based VIB researchers have revealed a mechanism that explains why the anti-tumor activity of specific immune cells called macrophages is suppressed during tumor growth. They have also demonstrated that blocking the protein Nrp1 can restore this anti-tumor immune response.

12 Dec 2013

Scientists develop new technique that results in better ways to relieve pain, monitor healing

Understanding the science behind pain, from a simple "ouch" to the chronic and excruciating, has been an elusive goal for centuries. But now, researchers are reporting a promising step toward studying pain in action.

12 Dec 2013

HSET protein could help doctors identify aggressive breast cancers in African-American patients

African-American women who get breast cancer often get more aggressive forms of the disease and at younger ages than other women.

12 Dec 2013

People more likely to seek info on quitting smoking when media covers celebrities with cancer

Millions of people will make a resolution to quit smoking around Jan. 1, but a new study suggests an even more powerful motivator than New Year's resolutions: celebrity cancer diagnoses.

12 Dec 2013

HCV antiviral therapy also improves diabetes outcomes

Researchers from Taiwan reveal that antiviral therapy for hepatitis C virus improves kidney and cardiovascular outcomes for patients with diabetes. Results of the study published in Hepatology, a journal of the American Association for the Study of Liver Diseases, show that incidences of kidney disease, stroke, and heart attack were lower in patients treated with pegylated interferon and ribavirin compared to HCV patients not treated with antivirals or diabetic patients not infected with the virus.

12 Dec 2013

Tumor-infiltrating lymphocytes may be good biomarker of response to trastuzumab in breast cancer

Women with HER2-positive breast cancer who had the highest levels of immune cells in their tumors gained the most benefit from presurgery treatment with chemotherapy and trastuzumab, according to results presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

12 Dec 2013

Cardiologist offers tips to keep heart healthy during holiday season

Physicians have long recognized a "holiday bump" in the number of heart attacks at this time of year. "It's small, but it's something that we notice," said Renato Santos, M.D., an interventional cardiologist at Wake Forest Baptist Medical Center.

12 Dec 2013

Researchers develop new screening tool to facilitate diagnosis of Autism Spectrum Disorder in adults

Researchers at Karolinska Institutet in Sweden have developed a new screening tool to facilitate the diagnosis of Autism Spectrum Disorder in adults. The test is presented in the scientific journal Molecular Autism and is unique in that researchers have, as part of their evaluation, compared the group diagnosed with Autism Spectrum Disorder with psychiatric patients.

12 Dec 2013

New test to help physicians identify patients with most lethal forms of triple-negative breast cancer

A new test has the potential to help physicians identify patients with the most lethal forms of triple-negative breast cancer, a disease which requires aggressive and innovative treatment.

12 Dec 2013

Elevated BACE1 activity in mild cognitive impairment could be early indicator of AD, says study

The critical enzyme beta-secretase1 (BACE1) is known to be elevated in brains with sporadic Alzheimer disease (AD). Scientists have now found increased levels of BACE1 in brains with mild cognitive impairment (MCI), suggesting that BACE1 activity is important for conversion of mild cognitive impairment to AD and may be an early indicator of AD.

12 Dec 2013

Researchers identify variations in gene that doubles risk of developing Alzheimer's disease

A team led by researchers at Washington University School of Medicine in St. Louis has identified variations in a gene that doubles a person's risk of developing Alzheimer's disease later in life.

12 Dec 2013

MedImmune, Johns Hopkins University enter into $6.5M research collaboration

MedImmune, AstraZeneca’s global biologics research and development arm, and The Johns Hopkins University today announced they have entered into a five-year, $6.5 million research collaboration.

12 Dec 2013

Two tumor-suppressing genes could play vital role in controlling obesity, cancer, diabetes

The function of two tumor-suppressing genes could play a vital role in helping to control obesity and other diseases such as diabetes, heart disease and cancer, according to researchers in Temple University's Sbarro Institute for Cancer Research and Molecular Medicine.

12 Dec 2013

Study finds link between consumption of foods from restaurants and obesity risk in African Americans

Americans are increasingly eating more of their meals prepared away from home, and this is particularly true among African Americans, who also have higher rates of obesity than other Americans. Young adults tend to eat out more often at fast-food restaurants and these establishments are more often found in minority neighborhoods.

12 Dec 2013

FDA Advisory Committee recommends metreleptin for treatment of generalized lipodystrophy

AstraZeneca and Bristol-Myers Squibb Company (NYSE:BMY) today announced the U.S. Food and Drug Administration's (FDA) Endocrinologic and Metabolic Drugs Advisory Committee (EMDAC) recommends the investigational medicine metreleptin for the treatment of pediatric and adult patients with generalized lipodystrophy (LD).

12 Dec 2013

Medical Condition News

Researchers refute avalanche theory on cancer

New guidelines to manage heart failure in children

Dementia much higher among Native Americans and African-Americans

Immunocellular Therapeutics reports positive results from ICT-107 Phase II study in glioblastoma patients

Queen's University to lead €6 million European study to find new treatments for bowel cancer

New mechanism explains why anti-tumor activity of specific immune suppressed during tumor growth

Scientists develop new technique that results in better ways to relieve pain, monitor healing

HSET protein could help doctors identify aggressive breast cancers in African-American patients

People more likely to seek info on quitting smoking when media covers celebrities with cancer

HCV antiviral therapy also improves diabetes outcomes

Tumor-infiltrating lymphocytes may be good biomarker of response to trastuzumab in breast cancer

Cardiologist offers tips to keep heart healthy during holiday season

Researchers develop new screening tool to facilitate diagnosis of Autism Spectrum Disorder in adults

New test to help physicians identify patients with most lethal forms of triple-negative breast cancer

Elevated BACE1 activity in mild cognitive impairment could be early indicator of AD, says study

Researchers identify variations in gene that doubles risk of developing Alzheimer's disease

MedImmune, Johns Hopkins University enter into $6.5M research collaboration

Two tumor-suppressing genes could play vital role in controlling obesity, cancer, diabetes

Study finds link between consumption of foods from restaurants and obesity risk in African Americans

FDA Advisory Committee recommends metreleptin for treatment of generalized lipodystrophy

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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