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Researchers identify biological process that appears to trigger Parkinson's disease

Working with human neurons and fruit flies, researchers at Johns Hopkins have identified and then shut down a biological process that appears to trigger a particular form of Parkinson's disease present in a large number of patients. A report on the study, in the April 10 issue of the journal Cell, could lead to new treatments for this disorder.

11 Apr 2014

Two Penn researchers selected as recipients of prestigious Clinical Research Achievement Award

Two researchers from the Perelman School of Medicine at the University of Pennsylvania and the Penn Cardiovascular Institute are among the 2014 recipients of the prestigious Clinical Research Achievement Award for their work in cardiovascular science.

11 Apr 2014

Studies shed light on propensity for habit formation in obsessive-compulsive disorder

Two new studies published this week in Biological Psychiatry shed light on the propensity for habit formation in obsessive-compulsive disorder (OCD). These studies suggest that a tendency to develop habits, i.e., the compulsive component of the disorder, may be a core feature of the disorder rather than a consequence of irrational beliefs.

11 Apr 2014

Loyola University Medical Center designated as Comprehensive Hypertension Center

Loyola University Medical Center has been approved as a Comprehensive Hypertension Center by the American Society of Hypertension. This designation recognizes centers that have demonstrated the highest level of expertise in treating patients with complex hypertension and co-existing medical conditions such as diabetes and chronic kidney disease.

11 Apr 2014

Researchers discover mechanism that control normal lung function in patients with BHD syndrome

Researchers at Penn Medicine have discovered that the tumor suppressor gene folliculin (FLCN) is essential to normal lung function in patients with the rare disease Birt-Hogg-Dube (BHD) syndrome, a genetic disorder that affects the lungs, skin and kidneys. Folliculin's absence or mutated state has a cascading effect that leads to deteriorated lung integrity and an impairment of lung function, as reported in their findings in the current issue of Cell Reports.

11 Apr 2014

Study looks at factors that influence life expectancy of childhood cancer survivors

Many factors influence the life expectancy of childhood cancer survivors: not getting enough exercise, being underweight, and being worried about their future health or their health insurance. These are the findings of research led by Cheryl Cox of the St. Jude Children's Research Hospital in the US, published in Springer's Journal of Cancer Survivorship. The study found that, on average, childhood cancer survivors passed away before they were 40 years old.

11 Apr 2014

Scientists discover potential cause of Parkinson’s disease

Researchers have discovered a process that appears to explain how a well known enzyme mutation triggers the neural deterioration seen in Parkinson’s disease.

10 Apr 2014

Experts connect sleep deprivation to elevated risk of developing diabetes

Excessive noise is a common cause for a loss of sleep. Now, experts connect sleep deprivation to an elevated risk of developing diabetes.

10 Apr 2014

New breakthrough for people with spinal cord injury

New research has generated an unprecedented breakthrough for people with spinal cord injury. CEO Duncan Wallace said that work carried out by US scientists published this week shows that recovery after spinal cord injury may be possible in ways that were previously unimaginable.

10 Apr 2014

Researchers win 2014 Joint Team Science Award to improve care for depression in low-income areas

A team of community leaders and researchers from UCLA and RAND has been awarded the 2014 Joint Team Science Award in recognition of a 10-year effort to conduct community engaged, population-based translational science to improve care for depression in low-income areas.

10 Apr 2014

Angelica sinensis polysaccharides alleviate neuronal cell injury caused by oxidative stress

According to traditional Chinese medicine, the roles of Angelica sinensis correlate with tonifying the blood and promoting its circulation. Recent studies have shown that extracts of Angelica sinensis have antioxidative and neuroprotective effects.

10 Apr 2014

Study: CD206-targeting Manocept platform may provide potential avenues to enhance diagnosis in Kaposi Sarcoma

Navidea Biopharmaceuticals, Inc. (NYSE MKT: NAVB), a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, today announced that collaborators from the University of California, San Francisco (UCSF) presented results at the 2014 American Association for Cancer Research (AACR) conference, April 5-9, 2014 in San Diego, CA, highlighting the potential utility of imaging agents derived from Navidea's Manocept™ platform in identifying affected tissues and lymph nodes in patients with Kaposi Sarcoma (KS).

10 Apr 2014

BioLineRx to initiate Phase 1/2 clinical trial on new drug candidate for CML treatment

BioLineRx, a clinical-stage biopharmaceutical company dedicated to identifying, in-licensing and developing promising therapeutic candidates, announced today that Prof. Arnon Nagler, Director of the Hematology Division and Bone Marrow Transplantation Center at Sheba Medical Center, Israel, has received final regulatory approval to evaluate BioLineRx's BL-8040 as a treatment for chronic myeloid leukemia (CML) in a Phase 1/2 clinical study.

10 Apr 2014

New discovery opens door to development of new treatments that stop progression of Parkinson's disease

A research led by the Research Institute Vall d'Hebron (VHIR), in which the University of Valencia participated, has shown that pathological forms of the α-synuclein protein present in deceased patients with Parkinson's disease are able to initiate and spread in mice and primates the neurodegenerative process that typifies this disease.

10 Apr 2014

AVEO joins with Biodesix to develop and commercialize ficlatuzumab for treatment of NSCLC

AVEO Oncology (NASDAQ: AVEO) and Biodesix, Inc. today announced that they have entered into a worldwide agreement to develop and commercialize AVEO's hepatocyte growth factor (HGF) inhibitory antibody ficlatuzumab, with a Biodesix® companion diagnostic test.

10 Apr 2014

Novel prediction model improves patient outcomes after paracetamol-induced acute liver failure

In the UK paracetamol toxicity is the most common cause of ALF and has a high mortality rate. It is estimated that 150 to 200 deaths and 15 to 20 LTs occur as a result of poisoning each year in England and Wales.

10 Apr 2014

Comprehensive genomic analysis of low-grade brain tumors sorts into three categories

Comprehensive genomic analysis of low-grade brain tumors sorts them into three categories, one of which has the molecular hallmarks and shortened survival of glioblastoma multiforme, the most lethal of brain tumors, researchers reported at the American Association for Cancer Research Annual Meeting 2014.

10 Apr 2014

Medical Condition News

Researchers identify biological process that appears to trigger Parkinson's disease

Two Penn researchers selected as recipients of prestigious Clinical Research Achievement Award

Studies shed light on propensity for habit formation in obsessive-compulsive disorder

Loyola University Medical Center designated as Comprehensive Hypertension Center

Researchers discover mechanism that control normal lung function in patients with BHD syndrome

Study looks at factors that influence life expectancy of childhood cancer survivors

Scientists discover potential cause of Parkinson’s disease

Experts connect sleep deprivation to elevated risk of developing diabetes

New breakthrough for people with spinal cord injury

Researchers win 2014 Joint Team Science Award to improve care for depression in low-income areas

Angelica sinensis polysaccharides alleviate neuronal cell injury caused by oxidative stress

Study: CD206-targeting Manocept platform may provide potential avenues to enhance diagnosis in Kaposi Sarcoma

BioLineRx to initiate Phase 1/2 clinical trial on new drug candidate for CML treatment

New discovery opens door to development of new treatments that stop progression of Parkinson's disease

AVEO joins with Biodesix to develop and commercialize ficlatuzumab for treatment of NSCLC

Novel prediction model improves patient outcomes after paracetamol-induced acute liver failure

Comprehensive genomic analysis of low-grade brain tumors sorts into three categories

Researchers reveal how cells respond to mechanical manipulation

Snack food with olestra speeds up removal of toxins in body

Researchers find that cancer gene require copper to promote tumor growth

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

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