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Gout, uric acid levels and risk of death: an interview with Professor Austin Stack, Graduate Entry Medical School, University of Limerick

Gout is a relatively common arthritic disease that affects about 4% (I in 25) of the population. It results from the deposition of uric acid in joints due to elevated blood levels and a resulting inflammation ensues which is very painful.

26 Jul 2013

FDA acknowledges receipt of NDA resubmission of dapagliflozin drug for treatment of type 2 diabetes

AstraZeneca (NYSE: AZN) and Bristol-Myers Squibb Company (NYSE: BMY) today announced that the U.S. Food and Drug Administration (FDA) has acknowledged receipt of the New Drug Application (NDA) resubmission for investigational drug dapagliflozin for the treatment of adults with type 2 diabetes.

26 Jul 2013

Takeda unbinds Phase 3 study of orteronel in patients with mCRPC that progressed post-chemotherapy

Takeda Pharmaceutical Company Limited ("Takeda") announced today that it has unblinded the ELM-PC 5 Phase 3 study (C21005) of orteronel plus prednisone compared to placebo plus prednisone in patients with metastatic, castration- resistant prostate cancer (mCRPC) that had progressed during or following chemotherapy based on the recommendation of the Independent Data Monitoring Committee (IDMC).

26 Jul 2013

Updated CVD risk audit to help GPs optimise patient management is now available online

With cardiovascular disease (CVD) causing a third of all deaths in Australia, NPS MedicineWise is encouraging GPs to stay up to date with their knowledge about CVD risk assessment and therapy.

26 Jul 2013

Inner ear supporting cells protect hair cells by secreting HSP70

An underlying cause of hearing loss is the death of sensory hair cells in the inner ear, which can be damaged in response to a variety of factors including the use of aminoglycoside antibiotics.

26 Jul 2013

Emergency physicians correctly identify nearly 100% of patients with Bell's palsy

Emergency physicians correctly identified nearly 100 percent of patients with Bell's palsy, the symptoms of which are nearly identical to potentially life-threatening diseases such as stroke and brain tumors.

26 Jul 2013

Some warn of 'overwhelming' mental illness care cost without new research investment

Scientists warn health systems could face "overwhelming" costs of treating mental illness if no new money is invested in research.

26 Jul 2013

Epigenetic changes induced by ADO therapy prevent epilepsy progression

Epilepsy is characterized by recurrent seizures that present in many different ways. In some cases epileptic patients exhibit a progressive increase in both frequency and severity of seizures. Epigenetic changes such as DNA methylation have recently been implied as an underlying cause of several neurologic disorders, including epilepsy.

26 Jul 2013

Finding could aid in delivering personalized cancer medicine based on individual's genetics

Scientists at the Princess Margaret Cancer Centre have discovered a function of the tumor suppressor gene PTEN that helps explain why certain promising therapies fail in many cancer patients, a finding that could aid in delivering tailored, personalized cancer medicine based on an individual's genetics.

26 Jul 2013

Forest Laboratories, Pierre Fabre Laboratories announce that FETZIMA gets FDA approval for MDD

Forest Laboratories, Inc. and Pierre Fabre Laboratories announced today that FETZIMA (levomilnacipran extended-release capsules), a once-daily serotonin and norepinephrine reuptake inhibitor, discovered by Pierre Fabre Laboratories and co-developed by Forest Laboratories, Inc. was approved by the U.S. Food and Drug Administration for the treatment of Major Depressive Disorder in adults.

26 Jul 2013

EGFR mutation testing dropped once funding from pharmaceutical industry discontinued

Significant advances have taken place in the management of patients with advanced and metastatic non-small-cell lung cancer over the last 5 years. Traditionally, all advanced NSCLC patients were treated in a similar manner.

26 Jul 2013

Princeton University researcher explores seriousness of peanut allergy

The path of the peanut from a snack staple to the object of bans at schools, day care centers and beyond offers important insights into how and why a rare, life-threatening food allergy can prompt far-reaching societal change, according to a Princeton University researcher.

26 Jul 2013

Researchers explore impact of obesity on outcomes of patients with advanced non-small cell lung cancer

Obesity increases health risks for many things. Researchers wanted to know the impact of obesity on outcomes of patients with advanced non-small cell lung cancer. In the September issue of the International Association for the Study of Lung Cancer's journal, the Journal of Thoracic Oncology, researchers conclude that obese patients had superior outcomes early on in the study, but then experienced increased hazards.

26 Jul 2013

EPHB2 overexpressed in malignant pleural mesothelioma cell lines, find researchers

Malignant mesothelioma is a rare asbestos-associated malignancy with limited therapeutic options. Despite advances in the treatment, the median survival remains 12 months from the time of diagnosis. Increased understanding of the molecular basis for the diverse signaling pathways involved in cancer progression should promote the discovery of novel biomarkers for early diagnosis and potentially lead to more effective therapeutic tools for the disease.

26 Jul 2013

Researchers explain how gut bacteria can inactivate cardiac drugs

For decades, doctors have understood that microbes in the human gut can influence how certain drugs work in the body - by either activating or inactivating specific compounds, but questions have long remained about exactly how the process works.

26 Jul 2013

Frequency, duration of patient-doctor contact important for improving health of dialysis patients

Both the frequency and duration of patient-doctor contact during dialysis care vary appreciably across countries, and facilities with more frequent and longer contact had fewer patient deaths and hospitalizations, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

26 Jul 2013

Researchers uncover way to stop cancer cells using HIF-1 gene through synthetic biology approach

Scientists have discovered a new molecule that prevents cancer cells from responding and surviving when starved of oxygen and which could be developed into new treatments for the disease, according to new research published in the Journal of the American Chemical Society today (Friday).

26 Jul 2013

Ovary removal during hysterectomy protects against future risk of ovarian cancer

While ovary removal during hysterectomy protects against future risk of ovarian cancer, the decision to conserve the ovaries and the hormones they produce may have advantages for preventing heart disease, hip fracture, sexual dysfunction, and cognitive decline.

26 Jul 2013

Abbott's FreeStyle Precision Pro Blood Glucose and Beta-Ketone Monitoring System gets FDA clearance

Abbott today announced that it has received U.S. Food and Drug Administration clearance for its FreeStyle Precision Pro Blood Glucose and Beta-Ketone Monitoring System, an advanced blood glucose monitoring system designed to address the key needs of hospital customers: high accuracy, efficient operation, dual-band wireless access to immediate test results, and helps in the reduction of the risk of test strip cross-contamination.

26 Jul 2013

Fall sports seasons approaching, youth athletes need to start training to prevent heatstroke

With summer practice and fall sports seasons quickly approaching, youth athletes need to start training now to help prevent heat-related illnesses.

26 Jul 2013

Medical Condition News

Gout, uric acid levels and risk of death: an interview with Professor Austin Stack, Graduate Entry Medical School, University of Limerick

FDA acknowledges receipt of NDA resubmission of dapagliflozin drug for treatment of type 2 diabetes

Takeda unbinds Phase 3 study of orteronel in patients with mCRPC that progressed post-chemotherapy

Updated CVD risk audit to help GPs optimise patient management is now available online

Inner ear supporting cells protect hair cells by secreting HSP70

Emergency physicians correctly identify nearly 100% of patients with Bell's palsy

Some warn of 'overwhelming' mental illness care cost without new research investment

Epigenetic changes induced by ADO therapy prevent epilepsy progression

Finding could aid in delivering personalized cancer medicine based on individual's genetics

Forest Laboratories, Pierre Fabre Laboratories announce that FETZIMA gets FDA approval for MDD

EGFR mutation testing dropped once funding from pharmaceutical industry discontinued

Princeton University researcher explores seriousness of peanut allergy

Researchers explore impact of obesity on outcomes of patients with advanced non-small cell lung cancer

EPHB2 overexpressed in malignant pleural mesothelioma cell lines, find researchers

Researchers explain how gut bacteria can inactivate cardiac drugs

Frequency, duration of patient-doctor contact important for improving health of dialysis patients

Researchers uncover way to stop cancer cells using HIF-1 gene through synthetic biology approach

Ovary removal during hysterectomy protects against future risk of ovarian cancer

Abbott's FreeStyle Precision Pro Blood Glucose and Beta-Ketone Monitoring System gets FDA clearance

Fall sports seasons approaching, youth athletes need to start training to prevent heatstroke

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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