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Clinical trial shows type-1 diabetes patients treated with teplizumab exhibit greater response to therapy

Primary results from a new clinical trial show that patients with type 1 diabetes treated with the monoclonal antibody teplizumab (MacroGenics, Inc.) exhibit greater preservation of C-peptide, a biomarker of islet cell function, compared to controls.

20 Aug 2013

Study examines ASDs recurrence risk for full and half-siblings

A Danish study of siblings suggests the recurrence risks for autism spectrum disorders (ASDs) varied from 4.5 percent to 10.5 percent depending on the birth years, which is higher than the ASD risk of 1.18 percent in the overall Danish population, according to a study published by JAMA Pediatrics, a JAMA Network publication.

20 Aug 2013

Study shows complement activation plays an important role in inherited macular degeneration

In a study published on line this week in the journal Human Molecular Genetics, Drs. Donita Garland, Rosario Fernandez-Godino, and Eric Pierce of the Ocular Genomics Institute at the Massachusetts Eye and Ear, Harvard Medical School, along with their colleagues, reported the unexpected finding that in mice genetically engineered to have an inherited form of macular degeneration, turning off the animals' complement system, a part of the immune system, prevented the disease.

20 Aug 2013

Scientists study how oxidative stress in cells impacts sarcopenia in all humans as they age

Although muscle cells did not reduce in size or number in mice lacking a protective antioxidant protein, they were weaker than normal muscle cells, researchers from the Barshop Institute for Longevity and Aging Studies at The University of Texas Health Science Center San Antonio found.

20 Aug 2013

Regular exercise can lessen back pain and insomnia for pregnant women

It may not be enough for women to spend just 30 minutes a day on a treadmill or elliptical if they want to manage their weight during pregnancy. Regular exercise can help lessen back pain, increase energy levels and reduce insomnia for pregnant women.

20 Aug 2013

Dunking in tub of ice water post-exercise decreases strength, soreness

Dunking in a tub of ice water after exercise - a surprisingly popular post-workout regimen used by athletes to reduce inflammation and speed recovery - is time consuming and bone-achingly painful. New research from the University of New Hampshire finds that it may not be effective, either.

20 Aug 2013

Study: Websites and mobile apps help fight obesity

A pending component of health care reform would require restaurants and vending machines to list calorie information on menus to help fight obesity.

20 Aug 2013

Copper enhances progression of Alzheimer's disease

Copper appears to be one of the main environmental factors that trigger the onset and enhance the progression of Alzheimer's disease by preventing the clearance and accelerating the accumulation of toxic proteins in the brain. That is the conclusion of a study appearing today in the journal Proceedings of the National Academy of Sciences.

20 Aug 2013

Report demonstrates clinical use of novel biomarker to assess cancer progression, inflammation

A groundbreaking peer reviewed case report by Dr. Isaac Eliaz, M.D. of Amitabha Medical Clinic, demonstrates for the first time the clinical use of novel biomarker galectin-3 to assess cancer progression and inflammation.

19 Aug 2013

New antibodies estimate risk of polyps developing into bowel cancer

Polyps in the mucosa of the colon are a common finding during screening colonoscopies. Some sub-groups of polyps are classed as precursors of bowel cancer. Until now, it has not been possible to precisely estimate the risk of these polyps developing into bowel cancer.

19 Aug 2013

New type of cancer immunotherapy harnesses body's immune system to attack tumors

By carefully adjusting the function of crucial immune cells, scientists may have developed a completely new type of cancer immunotherapy—harnessing the body's immune system to attack tumors. To accomplish this, they had to thread a needle in immune function, shrinking tumors without triggering unwanted autoimmune responses.

19 Aug 2013

Medical decision making for family member of cognitively impaired patient is more complicated

Decision-making by a surrogate for a family member who is unable to make medical decisions is more complicated than decision-making by patients themselves, according to a study from the Regenstrief Institute, Indiana University Center for Aging Research and the Charles Warren Fairbanks Center for Medical Ethics of Indiana University Health.

19 Aug 2013

Study: Gene that controls ageing process linked to cancer

A gene that helps control the ageing process by acting as a cell's internal clock has been linked to cancer by a major new study.

19 Aug 2013

FDA grants Orphan Drug Designation to Alnylam ALN-AT3 for treatment of hemophilia B

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, announced today that the U.S. Food & Drug Administration (FDA) has granted an Orphan Drug Designation to ALN-AT3 as a therapeutic for the treatment of hemophilia B.

17 Aug 2013

FDA grants Orphan Drug Designation to ADXS-HPV for treatment of HPV-associated anal cancer

Advaxis, Inc., (OTCQB: ADXS), a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announced that it has been granted Orphan Drug Designation from the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development (OOPD) for ADXS-HPV, its lead drug candidate, for the treatment of human papillomavirus (HPV)-associated anal cancer.

17 Aug 2013

Doctors suggest guidelines to prevent injuries caused by backpacks in children

Most children and teenagers carry their schoolbooks and other supplies in backpacks during the school year. "When used correctly, backpacks are the most efficient way to carry a load and distribute the weight among some of the body's strongest muscles," says Eric Wall, MD, Division of Orthopaedic Surgery.

17 Aug 2013

Secondary cancers in melanoma patients treated for BRAF gene mutation require new strategies

Moffitt Cancer Center researchers suggest secondary cancers seen in melanoma patients who are being treated for a BRAF gene mutation may require new strategies, such as enhanced surveillance and combining BRAF-inhibitor therapy with other inhibitors, especially as they become more widely used.

17 Aug 2013

Older heart patients present unique challenges for determining optimal dosages of medications

Older heart patients present unique challenges for determining the optimal dosages of medications, so a new study from researchers at Duke Medicine offers some rare clarity about the use of drugs that are used to treat patients with heart attacks.

17 Aug 2013

Basic cancer research at Creighton yields promising results for diagnosing, treating asthma

What started as basic cancer research at Creighton University has yielded promising results for diagnosing and treating asthma - and the National Institutes of Health (NIH) agrees, investing nearly $1.5 million in Creighton to find out more.

17 Aug 2013

Otolaryngologists to present newest specialty research in OTO EXPO

The 2013 Annual Meeting & OTO EXPOSM of the American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF), the largest meeting of ear, nose, and throat doctors in the world, will convene September 29 - October 2, at the Vancouver Convention Centre in Vancouver, BC, Canada.

17 Aug 2013

Medical Condition News

Clinical trial shows type-1 diabetes patients treated with teplizumab exhibit greater response to therapy

Study examines ASDs recurrence risk for full and half-siblings

Study shows complement activation plays an important role in inherited macular degeneration

Scientists study how oxidative stress in cells impacts sarcopenia in all humans as they age

Regular exercise can lessen back pain and insomnia for pregnant women

Dunking in tub of ice water post-exercise decreases strength, soreness

Study: Websites and mobile apps help fight obesity

Copper enhances progression of Alzheimer's disease

Report demonstrates clinical use of novel biomarker to assess cancer progression, inflammation

New antibodies estimate risk of polyps developing into bowel cancer

New type of cancer immunotherapy harnesses body's immune system to attack tumors

Medical decision making for family member of cognitively impaired patient is more complicated

Study: Gene that controls ageing process linked to cancer

FDA grants Orphan Drug Designation to Alnylam ALN-AT3 for treatment of hemophilia B

FDA grants Orphan Drug Designation to ADXS-HPV for treatment of HPV-associated anal cancer

Doctors suggest guidelines to prevent injuries caused by backpacks in children

Secondary cancers in melanoma patients treated for BRAF gene mutation require new strategies

Older heart patients present unique challenges for determining optimal dosages of medications

Basic cancer research at Creighton yields promising results for diagnosing, treating asthma

Otolaryngologists to present newest specialty research in OTO EXPO

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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