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Cleveland Clinic: Process that turns HDL cholesterol bad discovered

Cleveland Clinic researchers have discovered the process by which high-density lipoprotein (HDL) - the so-called "good cholesterol" - becomes dysfunctional, loses its cardio-protective properties, and instead promotes inflammation and atherosclerosis, or the clogging and hardening of the arteries.

26 Jan 2014

Focused ultrasound exam may accurately identify athletes with heart problems

A young athlete in seemingly excellent health dies suddenly from a previously undetected cardiovascular condition such as hypertrophic cardiomyopathy in nearly every U.S. state annually.

25 Jan 2014

New pain management system for patients with painful diabetic neuropathy

From the moment people learn to walk, many are taught that exercise is the key to living a healthy life. Indeed, the long-term benefits of exercise are indisputable.

25 Jan 2014

Gagnon Cardiovascular Institute adopt new medical device to treat patients with severe aortic stenosis

The Gagnon Cardiovascular Institute at Morristown Medical Center today became the first hospital in the tri-state area to adopt a new minimally invasive medical device to treat patients with severe aortic stenosis who are too ill or frail to have their aortic valves replaced trough traditional open-heart surgery.

25 Jan 2014

Researchers identify important steps to understand mechanisms underlying pathogenic effect of prions

"When they are healthy, they look like tiny spheres; when they are malignant, they appear as cubes" stated Giuseppe Legname, principal investigator of the Prion Biology Laboratory at the Scuola Internazionale Superiore di Studi Avanzati (SISSA) in Trieste, when describing prion proteins.

25 Jan 2014

First patient enrolled pilot clinical trial of NovoTTF Therapy plus gemcitabine for pancreatic adenocarcinoma

Novocure announced today that the first patient has enrolled in the EF-20 Study, an open label, pilot clinical trial of NovoTTF Therapy plus gemcitabine as first-line therapy for patients with locally advanced and metastatic pancreatic adenocarcinoma.

25 Jan 2014

UM professors receive grant to help athletes, military members suffering from traumatic brain injury

Athletes, members of the military and others suffering from traumatic brain injury may benefit from research conducted by two University of Montana faculty members through a new $300,000 grant awarded by General Electric Co. and the National Football League.

25 Jan 2014

Clinical trial of experimental vaccine targets cancer stem cells in patients with recurrent brain tumor

An early-phase clinical trial of an experimental vaccine that targets cancer stem cells in patients with recurrent glioblastoma multiforme, the most common and aggressive malignant brain tumor, has been launched by researchers at Cedars-Sinai's Department of Neurosurgery, Johnnie L. Cochran, Jr. Brain Tumor Center and Department of Neurology.

25 Jan 2014

Scientists develop powerful RapidCaP mouse models for metastatic prostate cancer

Prostate cancer is the most common form of cancer in men. Affecting about 1 in 6 men, it is the second deadliest cancer. Research has been stymied by imperfect animal models of the disease, which are costly, take considerable time to develop, and fail to mimic the most lethal aspects of the illness.

25 Jan 2014

Study shows impulsive personalities more likely to report higher levels of food addiction

The same kinds of impulsive behavior that lead some people to abuse alcohol and other drugs may also be an important contributor to an unhealthy relationship with food, according to new research from the University of Georgia.

25 Jan 2014

FDA to make recommendations on safety of oral tablets used to treat ragweed allergy symptoms

There is more to seasonal allergies than a little congestion and sneezing. If you notice eating watermelon, cantaloupe or avocado make you cough and itch, it may be a symptom of ragweed allergy. But more help might be on the way for some of the 23 million hay fever sufferers.

24 Jan 2014

Aspirin intake correlates with halted growth of lethal intracranial tumor

Researchers from Massachusetts Eye and Ear, Harvard Medical School, Massachusetts Institute of Technology and Massachusetts General Hospital have demonstrated, for the first time, that aspirin intake correlates with halted growth of vestibular schwannomas (also known as acoustic neuromas), a sometimes lethal intracranial tumor that typically causes hearing loss and tinnitus.

24 Jan 2014

Patient enrollment completed for Venaxis' pivotal clinical study of APPY1 Test

Venaxis, Inc., an in vitro diagnostic company focused on obtaining FDA clearance and commercializing its CE Marked APPY1 Test, a rapid, multiple biomarker-based assay for identifying patients that are at low risk for appendicitis, today announced completion of patient enrollment in its pivotal clinical study of the APPY1 Test in the United States.

24 Jan 2014

ADDF, Alzheimer's Society partner to provide funding for research in Alzheimer's disease

Today the Alzheimer's Drug Discovery Foundation and the Alzheimer's Society (UK) announced a new partnership that will provide funding for research in Alzheimer's disease and related dementias, with the goal of accelerating critical development programs and bringing new treatments to patients. The partnership intends to fund projects up to $1.5 million each focused on drug repurposing, leveraging existing scientific evidence and research to accelerate the drug development process.

24 Jan 2014

Researchers suggest possible novel target for seizure-blocking medicines

Researchers in the biomedical engineering department at Case Western Reserve University have found that epileptic activity can spread through a part of the brain in a new way, suggesting a possible novel target for seizure-blocking medicines.

24 Jan 2014

Early onset of dietary treatment may slow down progression of Alzheimer's disease

New research findings indicate that an early onset of dietary treatment may slow down the progression of Alzheimer's disease. The study was conducted on mice, and the results will be published in the February issue of Journal of Nutritional Biochemistry. Researchers from the University of Eastern Finland played a key role in the study, which was carried out as part of the LiPiDiDiet project funded by the European Union.

24 Jan 2014

FDA approves Miltenyi Biotec's CliniMACS CD34 Reagent System for prevention of GVHD

Miltenyi Biotec announced today that the U.S. Food and Drug Administration has approved the company's CliniMACS CD34 Reagent System as a Humanitarian Use Device for the prevention of graft-versus-host disease in patients with acute myeloid leukemia in first complete remission undergoing allogeneic stem cell transplantation from a matched related donor.

24 Jan 2014

FDA gives final approval to Perrigo's ANDA for repaglinide tablets 1 mg and 2 mg

Perrigo Company plc today announced that it has received final approval from the U.S. Food & Drug Administration for its abbreviated new drug application for repaglinide tablets 1 mg and 2 mg, the generic equivalent to Prandin Tablets (repaglinide tablets) and has commenced shipment of product. Perrigo previously launched the 0.5 mg strength in 2013.

24 Jan 2014

Research finds spousal diabetes is a diabetes risk factor

Living in a household implies sharing duties and responsibilities but it could also imply sharing your diabetes. A research team from the McGill University Health Centre (MUHC) has shown, through combined analyses of several studies, evidence that spousal diabetes is a diabetes risk factor. These findings, published today in the open access journal BMC Medicine, have important clinical implications since they can help improve diabetes detection and motivate couples to work together to reduce the risk of developing the condition.

24 Jan 2014

Selective FAK inhibition within endothelial cells prevents spontaneous tumor metastasis

A team of scientists, led by principal investigator David D. Schlaepfer, PhD, a professor in the Department of Reproductive Medicine at the University of California, San Diego School of Medicine, has found that a protein involved in promoting tumor growth and survival is also activated in surrounding blood vessels, enabling cancer cells to spread into the bloodstream.

24 Jan 2014

Medical Condition News

Cleveland Clinic: Process that turns HDL cholesterol bad discovered

Focused ultrasound exam may accurately identify athletes with heart problems

New pain management system for patients with painful diabetic neuropathy

Gagnon Cardiovascular Institute adopt new medical device to treat patients with severe aortic stenosis

Researchers identify important steps to understand mechanisms underlying pathogenic effect of prions

First patient enrolled pilot clinical trial of NovoTTF Therapy plus gemcitabine for pancreatic adenocarcinoma

UM professors receive grant to help athletes, military members suffering from traumatic brain injury

Clinical trial of experimental vaccine targets cancer stem cells in patients with recurrent brain tumor

Scientists develop powerful RapidCaP mouse models for metastatic prostate cancer

Study shows impulsive personalities more likely to report higher levels of food addiction

FDA to make recommendations on safety of oral tablets used to treat ragweed allergy symptoms

Aspirin intake correlates with halted growth of lethal intracranial tumor

Patient enrollment completed for Venaxis' pivotal clinical study of APPY1 Test

ADDF, Alzheimer's Society partner to provide funding for research in Alzheimer's disease

Researchers suggest possible novel target for seizure-blocking medicines

Early onset of dietary treatment may slow down progression of Alzheimer's disease

FDA approves Miltenyi Biotec's CliniMACS CD34 Reagent System for prevention of GVHD

FDA gives final approval to Perrigo's ANDA for repaglinide tablets 1 mg and 2 mg

Research finds spousal diabetes is a diabetes risk factor

Selective FAK inhibition within endothelial cells prevents spontaneous tumor metastasis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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