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Alnylam presents new pre-clinical data of ALN-CC5 for treatment of complement-mediated diseases

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has presented new pre-clinical data with ALN-CC5, an RNAi therapeutic targeting complement component C5.

21 Jun 2013

Researchers report therapeutic strategy that appears to destroy drug-resistant melanomas

An advanced tumor is a complex ecosystem. Though derived from a single cell, it evolves as it grows until it contains several subspecies of cells that vary dramatically in their genetic traits and behaviors.

21 Jun 2013

Research findings suggest potent new therapeutic target for certain types of cancer

Scientists have discovered the survival secret to a genetic mutation that stokes leukemia cells, solving an evolutionary riddle and paving the way to a highly targeted therapy for leukemia.

21 Jun 2013

Combination therapy with myxoma virus and rapamycin can kill glioblastoma multiforme

A combination of the myxoma virus and the immune suppressant rapamycin can kill glioblastoma multiforme, the most common and deadliest malignant brain tumor, according to Moffitt Cancer Center research.

21 Jun 2013

TSRI scientists find dual inhibitor that attacks two enzymes associated with Parkinson's disease

Scientists from the Florida campus of The Scripps Research Institute have found a compound that could counter Parkinson's disease in two ways at once.

21 Jun 2013

Scientists use stem-cell technology to create research cell line from PDAC patient

Pancreatic cancer carries a dismal prognosis. According to the National Cancer Institute, the overall five-year relative survival for 2003-2009 was 6 percent.

21 Jun 2013

Duke Medicine researchers identify molecular target to prevent onset of epilepsy

Duke Medicine researchers have identified a receptor in the nervous system that may be key to preventing epilepsy following a prolonged period of seizures.

21 Jun 2013

New treatment option for patients with aortic stenosis

Robert Stoler, MD, FACC, FSCAI, director of the Cardiac Catheterization Lab at Baylor Heart and Vascular Hospital and co-medical director, Division of Cardiology, is leading Baylor's participation in an exciting clinical trial to research a new treatment option for AS patients.

From Medtronic 21 Jun 2013

MIT study shows that SIRT1 gene plays key role in controlling circadian rhythms

Human sleeping and waking patterns are largely governed by an internal circadian clock that corresponds closely with the 24-hour cycle of light and darkness. This circadian clock also controls other body functions, such as metabolism and temperature regulation.

21 Jun 2013

New model developed to predict atrial fibrillation stroke risk factors

A more accurate and reliable stroke prediction model has been developed to help physicians decide whether to start blood-thinning treatment for patients with atrial fibrillation, as described in the current online issue of the Journal of the American Heart Association.

21 Jun 2013

Researchers receive NIH grant to study key proteins linked to cancer and diabetes

Researchers from the Polytechnic Institute of New York University and NYU have received a grant from the National Institutes of Health (NIH) to further a novel approach to understanding the genetic underpinnings of diseases including cancer and diabetes.

21 Jun 2013

Researchers discover key role of RAP1 gene in obesity

The discovery of an unexpected function for a gene that was associated to another process in the organism might be a solution in search of a problem, a clue to unsuspected connections. That is what has happened with RAP1, a gene that protects telomeres- the ends of chromosomes-after researchers from the Spanish National Cancer Research Centre surprisingly discovered its key role in obesity.

21 Jun 2013

Targeting particular signaling pathway can help prevent temporal lobe epilepsy, scientists report

Temporal lobe epilepsy, the most common form of epilepsy, is characterized by recurrent seizures throughout life and often behavioral abnormalities, with devastating impacts on patients and their families. Unfortunately, the condition is often not responsive to anticonvulsants. Now scientists report online June 20 in the Cell Press journal Neuron that targeting a particular signaling pathway in mice can prevent the development of temporal lobe epilepsy with just two weeks of treatment, offering hope that researchers will be able to develop effective drugs to mitigate recurrent seizures and the development of epilepsy.

21 Jun 2013

Laughing gas is associated with increased risk for perioperative cardiac events

A clinical trial published in the July issue of Anesthesiology may shed some light on whether nitrous oxide ("laughing gas") causes an increased risk for cardiac events, including heart attacks after surgery, particularly among high-risk patients.

20 Jun 2013

BerGenBio AS starts Phase 1 Clinical Trial for BGB324 oral AXL inhibitor

BerGenBio AS today announced the start of a Phase 1 Clinical Trial for BGB324, a first-in-class small molecule inhibitor of AXL tyrosine kinase. BGB324 is a highly selective, oral AXL inhibitor that blocks the epithelial-mesenchymal transition (EMT), which is a key driver of metastasis (cancer spread) and drug-resistance. The Phase 1 clinical trial of BGB324 is a single ascending dose study designed to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of BGB324.

20 Jun 2013

Certain factors and behaviors influence sexual hookups among first-year college women

Casual, no-strings sexual encounters are increasingly common on college campuses, but are some students more likely than others to "hook up"? A new study by researchers with The Miriam Hospital's Centers for Behavioral and Preventive Medicine, published online by the Archives of Sexual Behavior, suggests there are certain factors and behaviors associated with sexual hookups, particularly among first-year college women.

20 Jun 2013

Researchers monitor dynamic cellular events that take place during cardiac regeneration in zebrafish

In a study published in the June 19 online edition of the journal Nature, a scientific team led by researchers from the University of California, San Diego School of Medicine visually monitored the dynamic cellular events that take place when cardiac regeneration occurs in zebrafish after cardiac ventricular injury. Their findings provide evidence that various cell lines in the heart are more plastic, or capable of transformation into new cell types, than previously thought.

20 Jun 2013

Trees are effective tool in reducing air pollution and creating healthier urban environments

In the first effort to estimate the overall impact of a city's urban forest on concentrations of fine particulate pollution (particulate matter less than 2.5 microns, or PM2.5), a U.S. Forest Service and Davey Institute study found that urban trees and forests are saving an average of one life every year per city. In New York City, trees save an average of eight lives every year.

20 Jun 2013

Study reports increasing number of pedestrian injuries caused by cell phone use

More than 1,500 pedestrians were estimated to be treated in emergency rooms in 2010 for injuries related to using a cell phone while walking, according to a new nationwide study.

20 Jun 2013

Genetic process that promotes cervical cancer warns about anti-viral therapies in certain cases

A new understanding of the genetic process that can lead to cervical cancer may help improve diagnosis of potentially dangerous lesions for some women, and also raises a warning flag about the use of anti-viral therapies in certain cases - suggesting they could actually trigger the cancer they are trying to cure.

20 Jun 2013

Medical Condition News

Alnylam presents new pre-clinical data of ALN-CC5 for treatment of complement-mediated diseases

Researchers report therapeutic strategy that appears to destroy drug-resistant melanomas

Research findings suggest potent new therapeutic target for certain types of cancer

Combination therapy with myxoma virus and rapamycin can kill glioblastoma multiforme

TSRI scientists find dual inhibitor that attacks two enzymes associated with Parkinson's disease

Scientists use stem-cell technology to create research cell line from PDAC patient

Duke Medicine researchers identify molecular target to prevent onset of epilepsy

New treatment option for patients with aortic stenosis

MIT study shows that SIRT1 gene plays key role in controlling circadian rhythms

New model developed to predict atrial fibrillation stroke risk factors

Researchers receive NIH grant to study key proteins linked to cancer and diabetes

Researchers discover key role of RAP1 gene in obesity

Targeting particular signaling pathway can help prevent temporal lobe epilepsy, scientists report

Laughing gas is associated with increased risk for perioperative cardiac events

BerGenBio AS starts Phase 1 Clinical Trial for BGB324 oral AXL inhibitor

Certain factors and behaviors influence sexual hookups among first-year college women

Researchers monitor dynamic cellular events that take place during cardiac regeneration in zebrafish

Trees are effective tool in reducing air pollution and creating healthier urban environments

Study reports increasing number of pedestrian injuries caused by cell phone use

Genetic process that promotes cervical cancer warns about anti-viral therapies in certain cases

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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