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Lambrolizumab shows significant antitumor activity in patients with advanced melanoma

Researchers from UCLA's Jonsson Comprehensive Cancer Center led by Dr. Antoni Ribas, professor of medicine in the division of hematology-oncology, report preliminary results showing significant antitumor activity with very manageable side effects from a new drug being tested in patients with advanced melanoma, the deadliest form of skin cancer.

3 Jun 2013

Experts to discuss on resuscitation efforts at Euroanaesthesia

One of the most difficult moments faced by anaesthetists and other healthcare staff is when to carry on attempts to resuscitate a person, and when those efforts should reasonably stop. This dilemma is the subject of a session at Euroanaesthesia, the annual congress of the European Society of Anaesthesiology.

3 Jun 2013

MRIgFU ablation therapy reduces pain in 67% of patients with bone tumors

Patients with cancer that has spread to their bones are often treated with radiation therapy to reduce pain. But if that treatment doesn't work, or can't be used again, a second, effective option now exists.

3 Jun 2013

Human tumors with MET amplification respond to MET inhibitor drugs

A subset of colorectal cancers responds to anti-epidermal growth factor receptor (anti-EGFR) therapies, but develops resistance within months. Among cancers that develop resistance to anti-EGFR therapy, some showed overexpression of a gene called MET, according to a study published in the June issue of Cancer Discovery, a journal of the American Association for Cancer Research.

3 Jun 2013

Study finds HER2 irregularities in 14 different advanced solid tumors

The HER2 growth-factor gene is known to be over-active in breast and gastro-esophageal cancers. But now, irregularities in the genes's expression - among them mutations, amplifications, substitutions, and translocations - have been found in 14 different advanced solid tumors.

3 Jun 2013

Sorafenib stops tumor growth, provides effective treatment for thyroid cancer patients

The kidney and liver cancer drug sorafenib holds metastatic thyroid cancer at bay for nearly twice as long as a placebo, according to results of a randomized phase III trial, which will be presented today by a researcher from the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania in a plenary session during the American Society of Clinical Oncology's annual meeting.

3 Jun 2013

Partners of HPV-related oral cancer patients have no increased prevalence of oral infections: Study

Spouses and long-term partners of patients with mouth and throat cancers related to infection with the human papilloma virus (HPV) appear to have no increased prevalence of oral HPV infections, according to results of a multicenter, pilot study led by Johns Hopkins investigators.

3 Jun 2013

Mount Sinai researchers present landmark studies at ASCO meeting

Icahn School of Medicine at Mount Sinai researchers will present several landmark studies at the 2013 American Society of Clinical Oncology meeting May 31-June 4, 2013 in Chicago, including data on the likelihood of spousal human papillomavirus oral infection, new gene signatures in melanoma, and issues with high readmission rates after cancer surgery.

3 Jun 2013

Selumetinib demonstrates clinical benefit for patients with metastatic uveal melanoma

The experimental drug selumetinib is the first targeted therapy to demonstrate significant clinical benefit for patients with metastatic uveal melanoma, according to new Memorial Sloan-Kettering Cancer Center research presented on Saturday, June 1, at the 49th annual meeting of the American Society of Clinical Oncology.

3 Jun 2013

New clinical trial may help reduce radiation dose for patients with HPV-positive oropharyngeal cancer

Researchers from Fox Chase Cancer Center and other institutions have completed a phase II clinical trial that may help identify those patients with HPV-positive oropharyngeal cancer who do not require the full radiation dose given in a standard regimen of Intensity-Modulated Radiation Therapy (IMRT). Preliminary findings will be presented by Shanthi Marur, first author on the study and an oncologist at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, at the 49th Annual Meeting of the American Society of Clinical Oncology on Sunday, June 2.

1 Jun 2013

Genetically engineered immune cells appear to promote healing in mice infected with MS-like disease

Genetically engineered immune cells seem to promote healing in mice infected with a neurological disease similar to multiple sclerosis (MS), cleaning up lesions and allowing the mice to regain use of their legs and tails.

1 Jun 2013

Study shows utility of cfDNA blood tests for breast cancer patients

Researchers from Chronix Biomedical and The University of Texas MD Anderson Cancer Center today announced that results from a pilot study demonstrating the utility of cell-free DNA (cfDNA) blood tests as a companion diagnostic for breast cancer patients are to be reported in a poster presentation titled "Modulation of breast cancer cell-free DNA with surgical resection" (Abstract #11060) at the American Society of Clinical Oncology Annual Meeting (ASCO 2013) being held from May 31 through June 4, 2013 in Chicago. The blood test detects cfDNA that is released into the blood stream by damaged and dying cancer cells.

1 Jun 2013

Twitter: A popular source for receiving and sharing new information about vaccines

Twitter is a popular source for receiving and sharing new information about vaccines, and also a basically reliable one, according to a study published in the June issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

1 Jun 2013

Ultrasound targeted to painful bone metastases brings significant relief with tolerable side effects

A high-dose of ultrasound targeted to painful bone metastases appears to quickly bring patients relief, and with largely tolerable side effects, according to new research presented by Fox Chase Cancer Center scientists at the 49th Annual Meeting of the American Society of Clinical Oncology on Monday, June 3.

1 Jun 2013

RBC transfusion during cardiac surgery can increase risk of postoperative infection

The risk of postoperative infection appears to increase when patients receive red blood cell (RBC) transfusion during or after cardiac surgery, and greater attention to practices that limit red blood cell use could potentially reduce the occurrence of major postoperative infections, according to a study published in the June 2013 issue of The Annals of Thoracic Surgery.

1 Jun 2013

Cytomegalovirus might accelerate the development of glioblastoma

A virus that infects most Americans but that usually remains dormant in the body might speed the progression of an aggressive form of brain cancer when particular genes are shut off in tumor cells, new research shows.

1 Jun 2013

New therapy for lung cancer produces manageable side effects

A promising new therapy for the most common form of lung cancer appears to produce largely manageable side effects, and an ongoing clinical trial is determining whether the compound treats tumors more effectively than what's on the market, according research that scientists at Fox Chase Cancer Center will present at the 49th Annual Meeting of the American Society of Clinical Oncology on Saturday, June 1.

1 Jun 2013

Elderly patients exposed to general anaesthesia face increased risk of developing dementia

Exposure to general anaesthesia increases the risk of dementia in the elderly by 35%, says new research presented at Euroanaesthesia, the annual congress of the European Society of Anaesthesiology (ESA). The research is by Dr Francois Sztark, INSERM and University of Bordeaux, France, and colleagues.

1 Jun 2013

Views held by some GPs: One of the greatest health risks from smoking is nicotine

A survey of GPs (general practitioners) in the UK and Sweden revealed that some hold the view that one of the greatest health risks from smoking is nicotine. This belief likely influences health advice to smokers when considering whether to recommend the use of alternative nicotine products.

1 Jun 2013

Study suggests bright light therapy may improve sleep and brain function post mild TBI

A new study suggests that bright light therapy may improve sleep, cognition, emotion and brain function following mild traumatic brain injury (TBI).

1 Jun 2013

Medical Condition News

Lambrolizumab shows significant antitumor activity in patients with advanced melanoma

Experts to discuss on resuscitation efforts at Euroanaesthesia

MRIgFU ablation therapy reduces pain in 67% of patients with bone tumors

Human tumors with MET amplification respond to MET inhibitor drugs

Study finds HER2 irregularities in 14 different advanced solid tumors

Sorafenib stops tumor growth, provides effective treatment for thyroid cancer patients

Partners of HPV-related oral cancer patients have no increased prevalence of oral infections: Study

Mount Sinai researchers present landmark studies at ASCO meeting

Selumetinib demonstrates clinical benefit for patients with metastatic uveal melanoma

New clinical trial may help reduce radiation dose for patients with HPV-positive oropharyngeal cancer

Genetically engineered immune cells appear to promote healing in mice infected with MS-like disease

Study shows utility of cfDNA blood tests for breast cancer patients

Twitter: A popular source for receiving and sharing new information about vaccines

Ultrasound targeted to painful bone metastases brings significant relief with tolerable side effects

RBC transfusion during cardiac surgery can increase risk of postoperative infection

Cytomegalovirus might accelerate the development of glioblastoma

New therapy for lung cancer produces manageable side effects

Elderly patients exposed to general anaesthesia face increased risk of developing dementia

Views held by some GPs: One of the greatest health risks from smoking is nicotine

Study suggests bright light therapy may improve sleep and brain function post mild TBI

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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