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Advaxis commences enrollment in ADXS-HPV Phase 1/2 study for head and neck cancer

Advaxis, Inc.,, a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announced that two patients have been enrolled into REALISTIC, a Phase 1/2 study being sponsored by Cancer Research UK (CRUK) to investigate the use of ADXS-HPV for the treatment of HPV positive head and neck cancer. HPV is associated with 40-70% of head and neck cancers.

8 May 2012

Covidien to unveil new OneShot renal denervation system at EuroPCR congress

Covidien, a leading global provider of healthcare products, will unveil its new OneShot renal denervation system at the EuroPCR congress in Paris, France, on May 16, 2012. Adding to the Company's broad and growing vascular therapies portfolio, the OneShot system is designed to treat patients with hypertension who are not responsive to traditional medical therapy.

8 May 2012

FDA approves St. Jude Medical's Assura family of implantable defibrillators

St. Jude Medical, Inc., a global medical device company, today announced U.S. Food and Drug Administration (FDA) approval of its Assura portfolio of implantable cardioverter defibrillators (ICDs) and cardiac resynchronization therapy defibrillators (CRT-Ds).

8 May 2012

U.S. healthcare system could be burdened with 32 million more obese people within two decades

Researchers have forecast the cost savings and rise in obesity prevalence over the next two decades in a new public health study.

8 May 2012

Amakem presents key preclinical data on AMA0076 at ARVO meeting

Amakem NV, a kinase platform company focusing on ophthalmology, presented key preclinical data on its potent, locally active Rho Kinase (ROCK) inhibitor AMA0076 at the 2012 Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting being held at Fort Lauderdale, US from 6 - 10 May. The ARVO meeting is the world's largest gathering of international eye and vision researchers.

8 May 2012

LAA occlusion effectively reduces risk of stroke in patients with A-fib

Patients with atrial fibrillation (A-fib) who cannot take blood thinners now have an alternative to reduce their risk of stroke, which is five times more common in people with the rhythm disorder. The non-surgical procedure works by tying off the left atrial appendage (LAA), the source of most blood clots leading to stroke in patients with A-fib. Northwestern Medicine- heart rhythm specialists from the Bluhm Cardiovascular Institute were the first to perform this procedure in Illinois.

8 May 2012

TV viewing linked to unhealthy eating habits in U.S. adolescents

Television viewing and unhealthy eating habits in U.S. adolescents appear to be linked in a national survey of students in the fifth to 10 th grades, according to a report published in the May issue of Archives of Pediatrics & Adolescent Medicine, a JAMA Network publication. The study is part of the Nutrition and the Health of Children and Adolescents theme issue.

8 May 2012

Mothers of overweight toddlers less likely to accurately perceive their child's body size

A study of mothers and their toddlers suggests that mothers of overweight toddlers often had inaccurate perceptions of their child's body size, according to a report published in the May issue of Archives of Pediatrics & Adolescent Medicine, a JAMA Network publication. The study is part of the Nutrition and the Health of Children and Adolescents theme issue.

8 May 2012

Metformin blocks uveitis in laboratory rats

University of Texas Medical Branch at Galveston researchers have discovered that a drug already prescribed to millions of people with diabetes could also have another important use: treating one of the world's leading causes of blindness.

8 May 2012

Repeating trinucleotide a strong predictor of Fuchs' dystrophy

Mayo Clinic and University of Oregon researchers have confirmed that a genetic factor called a repeating trinucleotide is a strong predictor of an individual's risk of developing the eye condition Fuchs' dystrophy. The findings were being presented today at the annual conference of the Association for Research in Vision and Ophthalmology in Orlando, Fla.

8 May 2012

New analysis on why some soldiers never seek PTSD care

U.S. Army researcher Maj. Gary H. Wynn, M.D., shared new analysis on why some Soldiers suffering from combat-related post-traumatic stress disorder (PTSD) never seek care or drop out of treatment early during a presentation today at the American Psychiatric Association's annual meeting. His presentation, "Epidemiology of Combat-Related PTSD in U.S. Service Members: Lessons Learned," also described the approaches the Army is using to address this issue and improve overall patient outcomes.

8 May 2012

MD Anderson dermatologists applaud upcoming FDA changes to sunscreen labels

Sunscreen labels can be confusing and at times misleading. That's why dermatologists at The University of Texas MD Anderson Cancer Center applaud the upcoming U.S. Food and Drug Administration (FDA) label changes that help consumers understand exactly what they're buying.

8 May 2012

Scientists make important discovery about internal programming of B cells

Scientists at The Scripps Research Institute have made an important discovery about the internal programming of B cells, the immune cells that make antibodies against infections. The finding opens the way for the development of vaccines that can work more efficiently and hints at therapies for conditions in which B cells cause harm—such as the autoimmune disease lupus erythymatosus, severe allergies, and B-cell lymphomas.

8 May 2012

Survey: Many people do not know how to spot skin cancer

Doing a little detective work can go a long way in finding skin cancer, the most common form of cancer diagnosed in the United States, at its earliest, most treatable stage. However, a new survey found that many people do not know how to spot skin cancer and are unaware of their risk of developing the disease.

8 May 2012

Long-term exposure to roadways linked with increased risk of death in patients with heart attack

Living close to a major highway poses a significant risk to heart attack survivors, reinforcing the need to isolate housing developments from heavy traffic areas, a Beth Israel Deaconess Medical Center study concludes.

8 May 2012

Research reveals possible strategy to reverse fibrosis in liver and other organs

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, report that significant numbers of myofibroblasts - cells that produce the fibrous scarring in chronic liver injury - revert to an inactive phenotype as the liver heals. The discovery in mouse models could ultimately help lead to new human therapies for reversing fibrosis in the liver, and in other organs like the lungs and kidneys.

8 May 2012

Viewpoints: Diabetes, future health ills & the GOP; Debate on FDA OTC plan; Sen. Brown's daughter's health insurance

A study of diabetes in overweight and obese youngsters bears an ominous warning about future health care trends in this country. It found that Type 2 diabetes, a new scourge among young people, progresses faster and is harder to treat in youngsters than in adults. ... Congressional Republicans, meanwhile, are bent on dismantling health care reforms that could greatly assist in curbing the obesity epidemic.

8 May 2012

Rare form of dementia eats away at personality and language

Michael French suffered from a rare form of dementia. It made him do unwise things like throwing away tax documents, getting a ticket for trying to pass an ambulance and buying stock in companies that were obviously in trouble. He seemed withdrawn and no longer spoke to his wife over dinner. He also lost his job at the consulting firm. This happened in 2006. His wife found he had changed suddenly from the smart, good-natured, hardworking man and was considering divorce when his ailment came into the picture.

8 May 2012

Breast cancer in men rarer but more deadly than in women

“Men with breast cancer don't do as well as women with breast cancer, and there are opportunities to improve that,” said study author Dr. Jon Greif, a breast surgeon in San Francisco. “They were less likely to get the standard treatments that women get.” Survival rates for men with breast cancer, overall, are lower than those for women, at least when it is diagnosed in the early stages, Greif found. The cancers differ in other respects too.

8 May 2012

Soon a single therapy for range of brain diseases like Parkinson’s and Alzheimer’s

In a study, published in Nature, researchers prevented brain cells dying in mice with prion disease. It is hoped the same method for preventing brain cell death could apply in other diseases. The findings are at an early stage, but have been heralded as “fascinating”.

8 May 2012