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Adult stem cells combined with new drug could hold key to curing type 1 diabetes

Millions of people with type 1 diabetes depend on daily insulin injections to survive. They would die without the shots because their immune system attacks the very insulin-producing cells it was designed to protect. Now, a University of Missouri scientist has discovered that this attack causes more damage than scientists realized. The revelation is leading to a potential cure that combines adult stem cells with a promising new drug.

29 May 2013

Cancer: The No. 1 health concern among middle-income Americans

Cancer is the No. 1 health concern among our country's middle-income Americans, according to a new study released by Washington National Institute for Wellness Solutions.

29 May 2013

Targacept initiates TC-5214 Phase 2b clinical study in patients with OAB

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today announced the initiation of a Phase 2b clinical study of TC-5214 as a treatment for overactive bladder.

29 May 2013

Pacira Pharmaceuticals reports results of EXPAREL Phase 2/3 clinical trial for TKA

Pacira Pharmaceuticals, Inc. today announced findings from the completed first part of its Phase 2/3 clinical trial assessing the use and administration of EXPAREL (bupivacaine liposome injectable suspension) as a single-dose injection femoral nerve block for total knee arthroplasty surgery.

29 May 2013

Perrigo receives final approval for generic Sanctura XR

Perrigo Company today announced that it has received final approval for the generic version of Sanctura XR. Perrigo had previously prevailed in litigation at both the district and appellate levels. The product has begun shipping immediately.

29 May 2013

Atopix awarded grant to pursue development of OC459 for atopic dermatitis

Atopix Therapeutics Ltd, a biopharmaceutical company developing a novel class of anti-allergic medicines, has been awarded a £1.7 million grant from the UK Biomedical Catalyst fund to pursue development of OC459 in the treatment of moderate-to-severe atopic dermatitis (a form of eczema).

29 May 2013

Viewpoints: 'Good news' on Calif. insurance rates; Battle against dementia needs stronger efforts; Dental care for the disabled

The Affordable Care Act, a k a Obamacare, goes fully into effect at the beginning of next year, and predictions of disaster are being heard far and wide. ... No doubt there will be problems, as there are with any large new government initiative, and in this case, we have the added complication that many Republican governors and legislators are doing all they can to sabotage reform. Yet important new evidence - especially from California, the law's most important test case - suggests that the real Obamacare shock will be one of unexpected success (Paul Krugman, 5/26).

29 May 2013

Survival rates increased among patients who received blood stem cell transplants: Study

Survival rates have increased significantly among patients who received blood stem cell transplants from both related and unrelated donors, according to a study published in the Journal of Clinical Oncology today.

29 May 2013

Protein presenilin plays critical role in controlling neuronal traffic on microtubule highways

Imagine if you could open up your brain and look inside. What you would see is a network of nerve cells called neurons, each with its own internal highway system for transporting essential materials between different parts of the cell.

29 May 2013

EMA grants Sucampo orphan drug designation for unoprostone isopropyl to treat retinitis pigmentosa

Sucampo Pharmaceuticals, Inc., a global biopharmaceutical company, today announced that it has received orphan drug designation in the European Union for unoprostone isopropyl for the treatment of retinitis pigmentosa (RP). RP is a genetic disease characterized by progressive, irreversible vision loss and decreasing visual acuity, and there are no drugs or therapeutic procedures currently approved for the treatment of RP today.

29 May 2013

UCLA researchers show that bacteria ingested in food can affect brain function

UCLA researchers now have the first evidence that bacteria ingested in food can affect brain function in humans. In an early proof-of-concept study of healthy women, they found that women who regularly consumed beneficial bacteria known as probiotics through yogurt showed altered brain function, both while in a resting state and in response to an emotion-recognition task.

29 May 2013

Spherical nanoparticles transform into netlike structures at site of cancer

Scientists at the University of California, San Diego, have designed tiny spherical particles to float easily through the bloodstream after injection, then assemble into a durable scaffold within diseased tissue. An enzyme produced by a specific type of tumor can trigger the transformation of the spheres into netlike structures that accumulate at the site of a cancer, the team reports in the journal Advanced Materials this week.

29 May 2013

Scientists identify role of GSK-3 alpha protein in promoting oncogenic KRAS function

While the mutated KRAS oncogene is associated with many cancers, it has not yet been successfully targeted by a therapeutic agent. Scientists are trying to find another way to target the gene by blocking signals from another protein downstream.

29 May 2013

Transplantation of human stem cells improves muscle function in rats used to model ALS

Transplantation of human stem cells in an experiment conducted at the University of Wisconsin-Madison improved survival and muscle function in rats used to model ALS, a nerve disease that destroys nerve control of muscles, causing death by respiratory failure.

29 May 2013

Residents need to help elderly neighbors, relatives keep safe during the heat wave

With the first heat wave of the season poised to descend on the Northeast, Dr. Thomas Cavalieri, a geriatrician and the dean of the University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine, is reminding residents to check on elderly neighbors and relatives who may not be aware of the dangers that come with hot weather.

29 May 2013

START team examines surgery-free treatment for people with knee osteoarthritis

Lindsay Tise is not the guy you would expect to see pumping iron at the gym. At 94 years old, he suffers from knee osteoarthritis, a debilitating yet common ailment for older Americans that makes physical activity both difficult and painful.

29 May 2013

New test to predict increased risk of death, hospitalization among kidney dialysis patients

Johns Hopkins scientists report that a 10-minute test for "frailty" first designed to predict whether the elderly can withstand surgery and other physical stress could be useful in assessing the increased risk of death and frequent hospitalization among kidney dialysis patients of any age.

29 May 2013

Digital chest tomosynthesis holds promise as first-line screening tool for lung cancer

Most lung cancers are detected when patients become symptomatic and have late-stage disease. However, recently, computed tomography creening for lung cancer has been reported to reduce lung cancer mortality.

29 May 2013

Research discovery may lead to development of new therapies for neurological disorders

For several years, the pharmaceutical industry has tried to develop drugs that target a specific neurotransmitter receptor in the brain, the NMDA receptor. This receptor is present on almost every neuron in the human brain and is involved in learning and memory. NMDA receptors also have been implicated in several neurological and psychiatric conditions such as Alzheimer's disease, Parkinson's disease, schizophrenia and depression.

29 May 2013

Unique omega-3 supplement improves lung function, reduces airway inflammation in asthmatics

An Indiana University study has found that a unique omega-3 supplement derived from the New Zealand green-lipped mussel significantly improved lung function and reduced airway inflammation in asthmatics who experience exercise-induced bronchoconstriction, also called exercise-induced asthma.

29 May 2013

Medical Condition News

Adult stem cells combined with new drug could hold key to curing type 1 diabetes

Cancer: The No. 1 health concern among middle-income Americans

Targacept initiates TC-5214 Phase 2b clinical study in patients with OAB

Pacira Pharmaceuticals reports results of EXPAREL Phase 2/3 clinical trial for TKA

Perrigo receives final approval for generic Sanctura XR

Atopix awarded grant to pursue development of OC459 for atopic dermatitis

Viewpoints: 'Good news' on Calif. insurance rates; Battle against dementia needs stronger efforts; Dental care for the disabled

Survival rates increased among patients who received blood stem cell transplants: Study

Protein presenilin plays critical role in controlling neuronal traffic on microtubule highways

EMA grants Sucampo orphan drug designation for unoprostone isopropyl to treat retinitis pigmentosa

UCLA researchers show that bacteria ingested in food can affect brain function

Spherical nanoparticles transform into netlike structures at site of cancer

Scientists identify role of GSK-3 alpha protein in promoting oncogenic KRAS function

Transplantation of human stem cells improves muscle function in rats used to model ALS

Residents need to help elderly neighbors, relatives keep safe during the heat wave

START team examines surgery-free treatment for people with knee osteoarthritis

New test to predict increased risk of death, hospitalization among kidney dialysis patients

Digital chest tomosynthesis holds promise as first-line screening tool for lung cancer

Research discovery may lead to development of new therapies for neurological disorders

Unique omega-3 supplement improves lung function, reduces airway inflammation in asthmatics

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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