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Impairment of daily rhythms has multiple adverse effects on human health

If you're counting calories to lose weight, that may be only part of the weight loss equation says a new research report published online in The FASEB Journal.

7 May 2012

Positive long-term outcome data for chronic ITP patients treated with rituxamab

A new analysis concludes that rituximab, a drug commonly used to treat blood cancers, leads to treatment responses lasting at least five years in approximately one quarter of patients with low platelet counts and a risk of bleeding due to chronic immune thrombocytopenic purpura (ITP).

7 May 2012

Vertex reports interim data from VX-809 and KALYDECO combination Phase 2 study for cystic fibrosis

Vertex Pharmaceuticals Incorporated announced today an interim analysis of data from an ongoing Phase 2 study of VX-809 and KALYDECO (ivacaftor) that showed significant improvements in lung function (FEV1) among adults with cystic fibrosis (CF) who have two copies.

7 May 2012

TOKU-E introduces faster dissolving dust-free grade Sodium Dodecyl Sulfate

TOKU-E Company has announced availability of their newly developed, innovative, ultra-safe, faster dissolving dust-free grade (DF) Sodium Dodecyl Sulfate (SDS).

7 May 2012

CardioKinetix Parachute Ventricular Partitioning Device trial data presented at 2012 EuroPCR

CardioKinetix Inc., a medical device company pioneering a catheter-based treatment for heart failure, today announced that clinical trial data from the first-of-its-kind Parachute Ventricular Partitioning Device for the treatment of patients with ischemic heart failure will be presented at the 2012 EuroPCR Conference in Paris.

7 May 2012

Positive results from PROLOR Biotech's hGH-CTP Phase II trial for growth hormone deficiency

PROLOR Biotech, Inc. today reported top-line results from a Phase II four-month treatment extension study of hGH-CTP, its long-acting version of human growth hormone, in growth hormone deficient adults.

7 May 2012

Galleon GAL-021 safe and well-tolerated in Phase I respiratory depression clinical study

Galleon Pharmaceuticals, a leader in the development of novel medicines to treat breathing disorders, today announced that its investigational drug GAL-021 appeared to be safe and well-tolerated and demonstrated dose-proportional pharmacokinetic effects on respiration in a Phase I clinical study of 30 healthy adults.

7 May 2012

Data from Idera IMO-8400 preclinical studies for SLE and psoriasis presented at AAI meeting

Idera Pharmaceuticals, Inc. today announced data from preclinical studies of IMO-8400, demonstrating a novel mechanism of action that may be applicable to the treatment of systemic lupus erythematosus (SLE) and psoriasis. IMO-8400 is an inhibitor of specific Toll-like receptors (TLRs).

7 May 2012

Positive results from Dainippon Sumitomo Pharma's LATUDA trials for bipolar I depression

Dainippon Sumitomo Pharma Co., Ltd. announced today results from two Phase 3 clinical trials designed to evaluate the efficacy and safety of LATUDA as adjunctive therapy and monotherapy, respectively, in patients with bipolar I depression (PREVAIL 1 and PREVAIL 2; PRogram to EValuate the Antidepressant Impact of Lurasidone).

7 May 2012

KYTHERA ATX-101-10-16 trial for submental fat meets primary endpoints

KYTHERA Biopharmaceuticals, Inc. today announced the presentation of initial trial results from Study ATX-101-10-16, the first of two pivotal European Phase III clinical trials with ATX-101, a facial injectable drug for the reduction of unwanted fat under the chin, or submental fat.

7 May 2012

Screening for diabetic retinopathy once every two years maybe safe, cost-effective

Research carried out at the Peninsula College of Medicine and Dentistry (PCMD), University of Exeter, has concluded that it would be a safe and cost-effective strategy to screen people with type 2 diabetes who have not yet developed diabetic retinopathy, for the disease once every two years instead of annually.

7 May 2012

New process cells use to produce proteins in low-oxygen environments

"How do bodily cells function when we are at a high altitude where the air contains little oxygen?"

7 May 2012

Researchers discover how diabetes affects specific brain area leading to memory loss

Badly controlled diabetes are known to affect the brain causing memory and learning problems and even an increased incidence of dementia, although how this occurs is not clear.

7 May 2012

No functional difference in effects of Lucentis and Avastin on preventing vision loss

The one year results from a study into whether two drug treatments (Lucentis and Avastin), are equally effective in treating neovascular or wet age-related macular degeneration (wet AMD), have been reported today at an international research meeting in Fort Lauderdale, Florida. The findings will also appear online shortly in the leading journal Ophthalmology.

7 May 2012

Automated way to record electrical activity inside neurons in the living brain

Gaining access to the inner workings of a neuron in the living brain offers a wealth of useful information: its patterns of electrical activity, its shape, even a profile of which genes are turned on at a given moment. However, achieving this entry is such a painstaking task that it is considered an art form; it is so difficult to learn that only a small number of labs in the world practice it.

7 May 2012

Brain networks may avoid traffic jams by communicating on different frequencies

Brain networks may avoid traffic jams at their busiest intersections by communicating on different frequencies, researchers at Washington University School of Medicine in St. Louis, the University Medical Center at Hamburg-Eppendorf and the University of T-bingen have learned.

7 May 2012

Cordoning off of lipids of the liver helps manage insulin resistance in the body

A Penn research team, led by Mitchell Lazar, MD, PhD, director of the Institute for Diabetes, Obesity, and Metabolism at the Perelman School of Medicine, University of Pennsylvania, reports in Nature Medicine that mice in which an enzyme called histone deacetylase 3 (HDAC3) was deleted had massively fatty livers, but lower blood sugar, and were thus protected from glucose intolerance and insulin resistance, the hallmark of diabetes.

7 May 2012

Eye color linked to high-risk for skin conditions

Eye color may be an indicator of whether a person is high-risk for certain serious skin conditions. A study, led by the University of Colorado School of Medicine, shows people with blue eyes are less likely to have vitiligo.

7 May 2012

Researchers make white fat take on characteristics of brown fat

Brown seems to be the color of choice when it comes to the types of fat cells in our bodies. Brown fat expends energy, while its counterpart, white fat stores it. The danger in white fat cells, along with the increased risk for diabetes and heart disease it poses, seems especially linked to visceral fat. Visceral fat is the build-up of fat around the organs in the belly.

7 May 2012

Oral nutriceutical restores vision to otherwise hopeless patients facing permanent loss

There may be new found hope for patients whose vision is threatened when medicine injected directly into the eyes fails to cause abnormal blood vessels to recede. While injectable drugs called angiogenesis (an-gee-oh-jen-esis) inhibitors are considered a modern miracle and have become the standard of care for patients with the fast-progressive form of macular degeneration, they are not foolproof.

7 May 2012

Medical Condition News

Impairment of daily rhythms has multiple adverse effects on human health

Positive long-term outcome data for chronic ITP patients treated with rituxamab

Vertex reports interim data from VX-809 and KALYDECO combination Phase 2 study for cystic fibrosis

TOKU-E introduces faster dissolving dust-free grade Sodium Dodecyl Sulfate

CardioKinetix Parachute Ventricular Partitioning Device trial data presented at 2012 EuroPCR

Positive results from PROLOR Biotech's hGH-CTP Phase II trial for growth hormone deficiency

Galleon GAL-021 safe and well-tolerated in Phase I respiratory depression clinical study

Data from Idera IMO-8400 preclinical studies for SLE and psoriasis presented at AAI meeting

Positive results from Dainippon Sumitomo Pharma's LATUDA trials for bipolar I depression

KYTHERA ATX-101-10-16 trial for submental fat meets primary endpoints

Screening for diabetic retinopathy once every two years maybe safe, cost-effective

New process cells use to produce proteins in low-oxygen environments

Researchers discover how diabetes affects specific brain area leading to memory loss

No functional difference in effects of Lucentis and Avastin on preventing vision loss

Automated way to record electrical activity inside neurons in the living brain

Brain networks may avoid traffic jams by communicating on different frequencies

Cordoning off of lipids of the liver helps manage insulin resistance in the body

Eye color linked to high-risk for skin conditions

Researchers make white fat take on characteristics of brown fat

Oral nutriceutical restores vision to otherwise hopeless patients facing permanent loss

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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