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Researchers discover new candidate disease proteins for neurodegenerative disorders

A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders.

4 Mar 2013

PsiOxus completes enrollment in MT-102 Phase II trial on cancer cachexia

PsiOxus Therapeutics, Ltd. (PsiOxus), a development stage biotechnology company, has completed patient enrollment for its Phase II clinical trial to study MT-102, a small molecule therapeutic for the treatment of cancer cachexia.

4 Mar 2013

Electronic health records increase colorectal cancer screening rates

Researchers used electronic health records to identify Group Health patients who weren't screened regularly for cancer of the colon and rectum-and to encourage them to be screened. This centralized, automated approach doubled these patients' rates of on-time screening-and saved health costs-over two years.

4 Mar 2013

Study finds how to shut down Bcl6 in diffuse large B-cell lymphoma

The powerful master regulatory transcription factor called Bcl6 is key to the survival of a majority of aggressive lymphomas, which arise from the B-cells of the immune system. The protein has long been considered too complex to target with a drug since it is also crucial to the healthy functioning of many immune cells in the body, not just B cells gone bad.

4 Mar 2013

Autistic children with severe language delay achieve phrase or fluent speech by age eight

New findings published in Pediatrics (Epub ahead of print) by the Kennedy Krieger Institute's Center for Autism and Related Disorders reveal that 70 percent of children with autism spectrum disorders (ASD) who have a history of severe language delay, achieved phrase or fluent speech by age eight.

4 Mar 2013

Chroma Therapeutics, CTI announce results from tosedostat Phase 2 study on AML

Cell Therapeutics, Inc. (CTI) and Chroma Therapeutics Ltd. announced today that Lancet Oncology has published results from the OPAL Phase 2 study of tosedostat in elderly patients with relapsed or refractory acute myeloid leukemia (AML).

4 Mar 2013

More than 60% of fire ant allergic patients do not adhere to treatment guidelines

Two million Americans are allergic to insect stings, an allergy which sends more than 500,000 people to the emergency room annually. Yet, according to a study published today in the March issue of Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAA), while fire ant allergy sufferers know allergy shots can save their life, more than 60 percent do not adhere to treatment guidelines.

4 Mar 2013

Children with ADHD more likely to have other psychiatric disorders as adults

The first large, population-based study to follow children with attention-deficit hyperactivity disorder (ADHD) into adulthood shows that ADHD often doesn't "go away," and that children with ADHD are more likely to have other psychiatric disorders as adults. Although numbers were small, they also appear more likely to commit suicide and are often incarcerated as adults.

4 Mar 2013

Older patients with head and neck cancers less likely to die in high-volume hospitals

A study of older patients with advanced head and neck cancers has found that where they were treated significantly influenced their survival.

4 Mar 2013

Study identifies how new ALS gene mutations cause other diseases of the brain, muscle and bone

Researchers supported by The ALS Association have discovered how mutations in new amyotrophic lateral sclerosis (ALS) genes cause not only ALS but also other diseases of the brain, muscle and bone.

4 Mar 2013

Poll shows compelling association between exercise and better sleep

Exercise can affect your sleep. The results of the National Sleep Foundation's 2013 Sleep in America poll show a compelling association between exercise and better sleep.

4 Mar 2013

Study instructs how to design new, more powerful vaccine formulas for cancer

Cancer vaccines that attempt to stimulate an immune system assault fail because the killer T cells aimed at tumors instead find the vaccination site a more inviting target, scientists at The University of Texas MD Anderson Cancer Center report in Nature Medicine.

4 Mar 2013

Investigators identify seven new genetic regions associated with AMD

An international group of investigators has identified seven new genetic regions associated with age-related macular degeneration (AMD), a common cause of blindness in older individuals. The findings, reported online March 3 in Nature Genetics, could point to new biological pathways and therapeutic targets for AMD.

4 Mar 2013

Researchers discover how LRRK2 mutations in familial Parkinson's damage brain cells

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the most common genetic mutations in familial Parkinson's disease damage brain cells.

4 Mar 2013

Study identifies two gene mutations that lead to death of nerve cells in ALS

A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and related degenerative diseases.

4 Mar 2013

Regeneron, Sanofi announce pooled data from Phase 1b trials with dupilumab for atopic dermatitis

Sanofi and Regeneron Pharmaceuticals, Inc. announced that pooled data from two Phase 1b trials with dupilumab (REGN668/SAR231893), an investigational, high-affinity, subcutaneously administered, fully-human antibody targeting the alpha subunit of the interleukin 4 receptor (IL-4R alpha), were presented at the 71st Annual Meeting of the American Academy of Dermatology (AAD) in Miami.

4 Mar 2013

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

A shortage of a protein called TDP-43 caused muscle wasting and stunted nerve cells. This finding supports the idea that malfunction of this protein plays a decisive role in ALS and FTD. The study is published in the "Proceedings of the National Academy of Sciences of the USA" (PNAS).

3 Mar 2013

Pregnancy-related foot changes may contribute to women's increased risk for arthritis

A new University of Iowa study confirms what many women have long suspected - that pregnancy permanently changes the size and shape of a woman's feet.

3 Mar 2013

D.C., N.Y. hospitals consider new team-ups, merger

Health systems and hospitals in Washington and New York City are joining forces: In Washington, health systems are forming a bond they say will improve pediatric care. In New York, a merger of hospitals is proposed.

3 Mar 2013

UNC1215 chemical probe can help investigate L3MBTL3 methyl-lysine reader domain

In an article published as the cover story of the March 2013 issue of Nature Chemical Biology, Lindsey James, PhD, research assistant professor in the lab of Stephen Frye, Fred Eshelman Distinguished Professor in the UNC School of Pharmacy and member of the UNC Lineberger Comprehensive Cancer Center, announced the discovery of a chemical probe that can be used to investigate the L3MBTL3 methyl-lysine reader domain.

3 Mar 2013

Medical Condition News

Researchers discover new candidate disease proteins for neurodegenerative disorders

PsiOxus completes enrollment in MT-102 Phase II trial on cancer cachexia

Electronic health records increase colorectal cancer screening rates

Study finds how to shut down Bcl6 in diffuse large B-cell lymphoma

Autistic children with severe language delay achieve phrase or fluent speech by age eight

Chroma Therapeutics, CTI announce results from tosedostat Phase 2 study on AML

More than 60% of fire ant allergic patients do not adhere to treatment guidelines

Children with ADHD more likely to have other psychiatric disorders as adults

Older patients with head and neck cancers less likely to die in high-volume hospitals

Study identifies how new ALS gene mutations cause other diseases of the brain, muscle and bone

Poll shows compelling association between exercise and better sleep

Study instructs how to design new, more powerful vaccine formulas for cancer

Investigators identify seven new genetic regions associated with AMD

Researchers discover how LRRK2 mutations in familial Parkinson's damage brain cells

Study identifies two gene mutations that lead to death of nerve cells in ALS

Regeneron, Sanofi announce pooled data from Phase 1b trials with dupilumab for atopic dermatitis

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

Pregnancy-related foot changes may contribute to women's increased risk for arthritis

D.C., N.Y. hospitals consider new team-ups, merger

UNC1215 chemical probe can help investigate L3MBTL3 methyl-lysine reader domain

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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