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NSCLC drug regimen approved in 2006 does not improve survival for older patients

Analysis of a drug regimen approved by the F.D.A. in 2006 for the treatment of non-small cell lung cancer (bevacizumab added to the standard chemotherapy regimen carboplatin and paclitaxel) finds Medicare insured patients age 65 years and older who received this regimen did not have improved survival compared to patients who received the standard treatment of carboplatin and paclitaxel alone, according to a study in the April 18 issue of JAMA.

18 Apr 2012

Excessive alcohol use associated with lower self-reporting of maturity

Tipping back one too many cocktails during an individual's early 20s doesn't correlate to a personal sense of immaturity; however if this habit doesn't stop as they reach age 30, young adults can feel psychologically underdeveloped, according to a University of Missouri study. Helping young adults acknowledge their mental impulse to "sober up" as they mature can improve substance abuse intervention programs.

18 Apr 2012

Kaposi's sarcoma-associated herpesvirus senses and reacts to host cell's impending death

A research team led by Children's National Medical Center has identified a trigger that causes latent Kaposi's sarcoma-associated herpesvirus (KSHV) to rapidly replicate itself. KSHV causes Kaposi's sarcoma, primary effusion lymphoma, and other cancers that commonly affect immunocompromised patients, including those with AIDS.

18 Apr 2012

Autologous HSPPC-96 vaccine clinically beneficial for GBM patients

Study results from a Phase II multicenter clinical trial tracking the impact that autologous heat shock protein-peptide vaccine (HSPPC-96) has on recurrent glioblastoma multiforme (GBM) patients showed that such a vaccine may be clinically beneficial.

18 Apr 2012

A guide to catch and treat hypertension early in children

High blood pressure in children and adolescents is a growing health problem that is often overlooked by physicians, according to a University of Michigan Health System article published in American Family Physician that offers doctors a guide to catching and treating hypertension early.

18 Apr 2012

Engineered particles tied to penetratin discover, deliver ligands for mitochondria, ribosomes

Scientists who developed a technology for identifying and targeting unique protein receptor ZIP Codes on the cellular surface have found a way to penetrate the outer membrane and deliver engineered particles - called iPhage - to organelles inside the cell.

18 Apr 2012

Addiction to opioids has higher risk of death than alcohol or other drugs

People with an opioid addiction had the highest risk of death when compared with rates for alcohol and other drugs, according to a new study by the Centre for Addiction and Mental Health (CAMH).

18 Apr 2012

Bevacizumab added to chemotherapy for NSCLC does not improve survival in elderly patients

Adding the drug bevacizumab (Avastin) to the standard chemotherapy regimen for non-small cell lung cancer (NSCLC) - an approach approved by the FDA in 2006 - did not lead to significantly increase survival rates for patients over the age of 65 enrolled in Medicare, a new study by Dana-Farber Cancer Institute researchers has found.

18 Apr 2012

Surgery to remove only the tumor preferable to removing entire kidney

Kidney cancer patients who had only their tumor removed had better survival than patients who had their entire kidney removed, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.

18 Apr 2012

Access reports positive interim results from MuGard Phase 4 clinical trial in oral mucositis

ACCESS PHARMACEUTICALS, INC., a biopharmaceutical company leveraging its proprietary drug-delivery platforms to develop treatments in areas of oncology and oncology supportive care, announced interim results from its ongoing MuGard Phase 4 clinical trial in oral mucositis.

18 Apr 2012

Study supports tolerability of low-dose aripiprazole as an antidepressant therapy-augmenting agent

In the current issue of Psychotherapy and Psychosomatics there is a negative study on the use of aripiprazole in depression.

18 Apr 2012

Role of inability to express emotions in cancer

A review published in the current issue of Psychotherapy and Psychosomatics raises the issue of the role of the inability to express emotions in cancer. Several interesting hypotheses emerge such as a possible link between alexithymia and the immune system, between alexithymia and quality of life, or between alexithymia, anxiety and depression.

18 Apr 2012

Caffeine increases eye's ability to produce tears

Researchers at the University of Tokyo's School of Medicine have shown for the first time that caffeine intake can significantly increase the eye's ability to produce tears, a finding that could improve treatment of dry eye syndrome. This common eye condition affects about four million people age 50 and older in the United States.

18 Apr 2012

New brain cancer vaccine with material from own tumors proves effective in clinical trial

A new brain cancer vaccine tailored to individual patients by using material from their own tumors has proven effective in a multicenter phase 2 clinical trial at extending their lives by several months or longer. The patients suffered from recurrent glioblastoma multiforme-which kills thousands of Americans every year.

18 Apr 2012

Fibrates to treat high cholesterol may affect kidney health

Older patients taking a common cholesterol medication should be cautious of the impact on their kidney health. In a new study by Dr. Amit Garg, Scientist at the Lawson Health Research Institute and the Institute for Clinical Evaluative Sciences (ICES), and colleagues, one in 10 new older fibrate users experienced a 50 per cent increase in their serum creatinine.

18 Apr 2012

Research on molecular mechanisms underlying Alzheimer's disease

Alzheimer's disease has been described as the "looming epidemic on the horizon." More than 5 million Americans currently suffer from this neurodegenerative disease that robs patients of their memories, and this number is projected to triple by the middle of the century.

18 Apr 2012

Idera commences IMO-3100 Phase 2 clinical trial for psoriasis

Idera Pharmaceuticals, Inc. today announced the treatment of the first patient in a Phase 2 clinical trial of IMO-3100, the Company's lead Toll-like receptor (TLR) inhibitor for the treatment of autoimmune diseases, in patients with moderate to severe plaque psoriasis.

18 Apr 2012

Medtronic plans IN.PACT Global drug-eluting balloon SFA clinical study

In conjunction with the Charing Cross International Symposium (CX34), which concludes today in London, Minneapolis-based Medtronic, Inc. announced its plans for the imminent start of the IN.PACT Global SFA clinical study, an international research program to evaluate the treatment of peripheral artery disease using the company's IN.PACT Admiral drug-eluting balloon.

From Medtronic 18 Apr 2012

Study tests effectiveness of personally tailored exercise programmes on young people with depression

A unique study to test the effectiveness of personally tailored exercise programmes on young people with depression has been launched by researchers at The University of Nottingham.

18 Apr 2012

Promising anti-diabetic substance found in liquorice root

It provides the raw material for liquorice candy, calms the stomach and alleviates diseases of the airways: liquorice root. Chosen as the "Medicinal plant 2012", the root has been treasured in traditional healing since ancient times. Researchers at the Max Planck Institute for Molecular Genetics in Berlin have now discovered that liquorice root also contains substances with an anti-diabetic effect.

18 Apr 2012

Medical Condition News

NSCLC drug regimen approved in 2006 does not improve survival for older patients

Excessive alcohol use associated with lower self-reporting of maturity

Kaposi's sarcoma-associated herpesvirus senses and reacts to host cell's impending death

Autologous HSPPC-96 vaccine clinically beneficial for GBM patients

A guide to catch and treat hypertension early in children

Engineered particles tied to penetratin discover, deliver ligands for mitochondria, ribosomes

Addiction to opioids has higher risk of death than alcohol or other drugs

Bevacizumab added to chemotherapy for NSCLC does not improve survival in elderly patients

Surgery to remove only the tumor preferable to removing entire kidney

Access reports positive interim results from MuGard Phase 4 clinical trial in oral mucositis

Study supports tolerability of low-dose aripiprazole as an antidepressant therapy-augmenting agent

Role of inability to express emotions in cancer

Caffeine increases eye's ability to produce tears

New brain cancer vaccine with material from own tumors proves effective in clinical trial

Fibrates to treat high cholesterol may affect kidney health

Research on molecular mechanisms underlying Alzheimer's disease

Idera commences IMO-3100 Phase 2 clinical trial for psoriasis

Medtronic plans IN.PACT Global drug-eluting balloon SFA clinical study

Study tests effectiveness of personally tailored exercise programmes on young people with depression

Promising anti-diabetic substance found in liquorice root

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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