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FDA-approved formoterol drug improves cognitive function in mouse model of Down syndrome

An existing FDA-approved drug improves cognitive function in a mouse model of Down syndrome, according to a new study by researchers at the Stanford University School of Medicine.

3 Jul 2013

Researchers find NRF2 signaling plays a role in growth of tumor cells by altering metabolic pathways

Cancer cells have alteration in metabolic pathways as a result of oncogenes that promote tumor growth. NRF2 (nuclear factor erythroid-derived 2-related factor 2) works as a "master gene" that turns on stress response by increasing numerous antioxidants and pollutant-detoxifying genes to protect the lungs from variety of air pollutants such as diesel exhaust and cigarette smoke.

3 Jul 2013

Ubiquitin protein may treat variety of diseases from Parkinson's to diabetes

A tiny protein called ubiquitin - so named because it is present in every cell of living things as dissimilar as hollyhocks and humans - may hold the key to treatment for a variety of diseases from Parkinson's to diabetes.

3 Jul 2013

BHR to demonstrate EKF Quo-Test HbA1c analyser at Heart UK's conference

EKF, announces today that the Quo-Test, its glycated haemoglobin analyser for near-patient monitoring of diabetes will be on show at Heart UK.

From EKF Diagnostics 2 Jul 2013

Alnylam Pharmaceuticals presents new pre-clinical data of ALN-AT3 at ISTH meeting

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has presented new pre-clinical data from its RNAi therapeutic program for the treatment of hemophilia and rare bleeding disorders.

2 Jul 2013

Study finds that long-term cannabis use affects motivation

Long-term cannabis users tend to produce less dopamine, a chemical in the brain linked to motivation, a study has found.

2 Jul 2013

ARIAD Pharmaceuticals' Iclusig gets EC marketing authorization for CML and Ph+ ALL treatment

ARIAD Pharmaceuticals, Inc. today announced that the European Commission has granted a marketing authorization for Iclusig (ponatinib) as an orphan medicinal product for two indications.

2 Jul 2013

State highlights: Calif. bill to fine firms with workers on Medi-Cal fails; Pa. eyes disallowing apologies used against doctors in court-proceedings

A California proposal to fine large companies that have workers on Medi-Cal came up short in an initial vote in the Assembly amid strong business opposition. The proposed fines could reach about $5,000 per full-time employee who receives Medi-Cal, the state Medicaid program for the poor. The bill, AB 880, garnered 46 votes in the 80-member chamber Thursday, short of the 54 votes, or two-thirds majority, needed. The measure could come up for reconsideration as early as next week (Terhune, 6/27).

2 Jul 2013

UCLA researchers introduce gene therapy technique to treat sickle cell disease

Researchers at UCLA's Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research have successfully established the foundation for using hematopoietic (blood-producing) stem cells from the bone marrow of patients with sickle cell disease to treat the disease.

2 Jul 2013

Research roundup: 'Welcome-mat' effect of Medicaid expansion; Setting up shops; California's transition to Medicaid managed care

The number of people eligible for Medicaid who remain uninsured varies from state to state, according to the authors. But the federal health law is likely to increase the rate of enrollment for this group. The potential impact of this increase in Medicaid enrollment, also known as the 'welcome-mat' effect, is unclear.

2 Jul 2013

Study offers new insights into how genome gets regulated by signalling molecules within human cells

There's not much difference between what makes a man and what makes his beer - at least at the molecular level - according to a new study led by Professor John Schwabe at the University of Leicester.

2 Jul 2013

African-American kids with T2D and risk for retinopathy are less likely to receive eye exam

In one of the few studies to provide information on eye screening of children, African-American children with the greatest risk for disease of the retina as a complication of Type 1 diabetes are the least likely to have received an eye exam, reports a team of researchers including senior author Terri H. Lipman of the University of Pennsylvania School of Nursing.

2 Jul 2013

Osteoarthritis associated genes: an interview with Professor Jonathan Tobias, University of Bristol

Joints are lined by articular cartilage, loss of which is one of the hallmarks of osteoarthritis. Articular cartilage is made up of a number of proteins, such as type II collagen. In rare forms of osteoarthritis, one of these structural proteins is defective as a result of a genetic mutation.

2 Jul 2013

UVA researchers identify promising target for treating glioblastoma

Researchers at the University of Virginia Cancer Center have identified a promising target for treating glioblastoma, one that appears to avoid many of the obstacles that typically frustrate efforts to develop effective treatments for this deadliest of cancers.

2 Jul 2013

FDA sends Complete Response Letter to Merck regarding investigational drug for insomnia

Merck, known as MSD outside the United States and Canada, announced today that the company has received a Complete Response Letter from the U.S. Food and Drug Administration (FDA) regarding the New Drug Application for suvorexant, Merck's investigational medicine for the treatment of insomnia.

2 Jul 2013

University of Chicago Celiac Disease Center to host ICDS 2013

The University of Chicago Celiac Disease Center is hosting the 15th International Celiac Disease Symposium (ICDS) on Sept. 22-25, 2013 in Chicago. The symposium is the largest celiac disease and gluten-related disorders conference in the world.

2 Jul 2013

Fondation Leducq grants $6M to cardiovascular scientists to help advance cardiac regeneration therapeutics

The Fondation Leducq in Paris, France, dedicated to improving human health through international efforts to combat cardiovascular disease, awarded a $6 million grant award to a new global research network of cardiovascular scientists which includes three researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai.

2 Jul 2013

New mechanism triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes

Researchers at NYU Langone Medical Center have discovered a mechanism that triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes. The results, published today in Nature Immunology, suggest a common biochemical thread to multiple diseases and point the way to a new class of therapies that could treat chronic inflammation in these non-infectious diseases without crippling the immune system.

2 Jul 2013

Study evaluates implementation of out-of hospital stroke policy in some Chicago hospitals

Implementing an out-of hospital stroke policy in some Chicago hospitals was associated with significant improvements in emergency medical services use and increased intravenous tissue plasminogen activator use at primary stroke centers, according to a study published by JAMA Neurology.

2 Jul 2013

Cannabis users appear to lack motivation

Researchers found that dopamine levels in a part of the brain called the striatum were lower in people who smoke more cannabis and those who began taking the drug at a younger age.

2 Jul 2013

Medical Condition News

FDA-approved formoterol drug improves cognitive function in mouse model of Down syndrome

Researchers find NRF2 signaling plays a role in growth of tumor cells by altering metabolic pathways

Ubiquitin protein may treat variety of diseases from Parkinson's to diabetes

BHR to demonstrate EKF Quo-Test HbA1c analyser at Heart UK's conference

Alnylam Pharmaceuticals presents new pre-clinical data of ALN-AT3 at ISTH meeting

Study finds that long-term cannabis use affects motivation

ARIAD Pharmaceuticals' Iclusig gets EC marketing authorization for CML and Ph+ ALL treatment

State highlights: Calif. bill to fine firms with workers on Medi-Cal fails; Pa. eyes disallowing apologies used against doctors in court-proceedings

UCLA researchers introduce gene therapy technique to treat sickle cell disease

Research roundup: 'Welcome-mat' effect of Medicaid expansion; Setting up shops; California's transition to Medicaid managed care

Study offers new insights into how genome gets regulated by signalling molecules within human cells

African-American kids with T2D and risk for retinopathy are less likely to receive eye exam

Osteoarthritis associated genes: an interview with Professor Jonathan Tobias, University of Bristol

UVA researchers identify promising target for treating glioblastoma

FDA sends Complete Response Letter to Merck regarding investigational drug for insomnia

University of Chicago Celiac Disease Center to host ICDS 2013

Fondation Leducq grants $6M to cardiovascular scientists to help advance cardiac regeneration therapeutics

New mechanism triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes

Study evaluates implementation of out-of hospital stroke policy in some Chicago hospitals

Cannabis users appear to lack motivation

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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