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Traumatic brain injury investigational treatment from BHR Pharma receives EMA orphan medicinal product designation

BHR Pharma, LLC announced today the European Medicines Agency (EMA), responsible for evaluating medicines developed for use in the European Union, granted an orphan medicinal product designation for treating moderate and severe traumatic brain injury (TBI) to its proprietary intravenous progesterone infusion agent, BHR-100. The agent currently is being evaluated as a neuroprotective treatment for severe traumatic brain injury (TBI) in the global, Phase III SyNAPSe® clinical trial.

14 Feb 2013

Threat vigilance can protect soldiers against PTSD

The onset of Post-Traumatic Stress Disorder (PTSD) is unpredictable. Because it depends on the unforeseeable occurrence of traumatic events, it is difficult to identify preventative or causative factors. Scientists typically turn to patients who have already developed PTSD to study the disorder, but that means they can't draw comparisons to their psychological state prior to experiencing trauma.

14 Feb 2013

Theradiag’s new biotherapy monitoring kits receive CE mark approval

Theradiag, a company specializing in theranostic and in vitro diagnostics, today announced it has obtained a CE mark for two new biotherapy monitoring kits; Tocilizumab (anti-IL6R) and Rituximab (anti-CD20) that further expand the Lisa Tracker range.

14 Feb 2013

Novel approach uses adult stem cells to save sight of diabetes sufferers

Scientists at Queen's University Belfast are hoping to develop a novel approach that could save the sight of millions of diabetes sufferers using adult stem cells.

14 Feb 2013

Link between Jagged-1 protein and bone formation

Researchers from the University of Pennsylvania School of Veterinary Medicine have discovered that a protein called Jagged-1 stimulates human stem cells to differentiate into bone-producing cells.

14 Feb 2013

Study identifies and discusses key factors that lead to obesity in pregnant women

A much neglected part of the obesity epidemic is that it has resulted in more overweight/obese women before and during pregnancy. Their offspring also tend to have higher birth weights and more body fat, and carry an increased risk of obesity and chronic diseases later in life. However, the nutritional factors and mechanisms involved pre and during pregnancy that may influence child obesity remain uncertain.

14 Feb 2013

FDA grants orphan drug status to Lentigen’s LG631-CD34 for treatment of glioblastoma multiforme

Lentigen Corporation, a biotechnology company specializing in the development and manufacture of lentiviral gene delivery products, announced today that that the U.S. Food and Drug Administration (FDA) has granted orphan drug status to P140K methylguanine methyltransferase (MGMT) transduced human CD34 cells for bone marrow protection in the treatment of glioblastoma multiforme.

14 Feb 2013

Mindfulness practitioners gain enhanced control over sensory cortical alpha rhythms

Why does training in mindfulness meditation help patients manage chronic pain and depression? In a newly published neurophysiological review, Brown University scientists propose that mindfulness practitioners gain enhanced control over sensory cortical alpha rhythms that help regulate how the brain processes and filters sensations, including pain, and memories such as depressive cognitions.

14 Feb 2013

New paper advances scientific understanding of glycoproteins’ structure and function

A Simon Fraser University chemist is the lead author on a new paper that advances scientific understanding of the structure and function of glycoproteins, in particular the number and positioning of sugars on them.

14 Feb 2013

Triple-negative breast cancers more biologically diverse than previously believed

Triple-negative breast cancers are more biologically diverse than previously believed and classification should be expanded to reflect this heterogeneity, according to University of North Carolina researchers.

14 Feb 2013

DBS can lead to long-term improvement in patients with neuropathic pain

For many patients with difficult-to-treat neuropathic pain, deep brain stimulation (DBS) can lead to long-term improvement in pain scores and other outcomes, according to a study in the February issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

14 Feb 2013

FDA grants final approval to Breckenridge’s Pioglitazone Hydrochloride ANDA

Breckenridge Pharmaceutical, Inc. announced today the immediate launch of Pioglitazone Hydrochloride Tablets. The U.S. Food and Drug Administration granted final approval for the Abbreviated New Drug Application (ANDA), which is being manufactured and supplied by Synthon Pharmaceuticals, Inc., and will be available in 15 mg, 30 mg, and 45 mg strengths.

14 Feb 2013

TP PCR methodology may help streamline genetic testing for Huntington's

A new test may help to streamline genetic testing for Huntington Disease (HD) by generating accurate results, avoiding unnecessary additional testing, and improving turnaround time.

14 Feb 2013

FDA allows Scioderm’s SD-101 IND application for Epidermolysis Bullosa to proceed

Scioderm announced that the US Food and Drug Administration (FDA) has reviewed and allowed the investigational new drug (IND) application for SD-101 to proceed. SD-101 is a topical treatment being developed for the treatment of Epidermolysis Bullosa (EB).

14 Feb 2013

CATT study clarifies value of genetic testing for age-related macular degeneration

New findings from a landmark clinical trial show that although certain gene variants may predict whether a person is likely to develop age-related macular degeneration (AMD), a potentially blinding eye disease that afflicts more than nine million Americans, these genes do not predict how patients will respond to Lucentis- and Avastin-, the two medications most widely used to treat the "wet" form of AMD.

13 Feb 2013

Examining politics of reaching NCD targets

Writing in the PLoS blog "Translational Global Health," Greg Paton, a public health consultant, discusses the history of and current discussions taking place surrounding global targets for non-communicable diseases (NCDs).

13 Feb 2013

Meridian receives ADA's Certificate of Education Recognition for diabetes education program

The American Diabetes Association (ADA) has awarded Meridian Medical Associates a Certificate of Education Recognition for its diabetes self-management education program.

13 Feb 2013

Researchers investigate new avenue of treatment to help boost poor pancreatic cancer survival rates

Researchers at Georgia Regents University Cancer Center are investigating a new avenue of treatment to help boost poor pancreatic cancer survival rates.

13 Feb 2013

Ability to tune gene activity will permit refined research for drug resistance, cancer

Scientists who built a synthetic gene circuit that allowed for the precise tuning of a gene's expression in yeast have now refined this new research tool to work in human cells, according to research published online in Nature Communications.

13 Feb 2013

Scientists identify aromatic rice with very low arsenic content

Millions of people worldwide are regularly exposed to arsenic through drinking water and eating rice grown in soil and water containing high amounts of arsenic. Long-term exposure can lead to the development of different types of cancer as well as serious cardiovascular, neurological, and other health problems. Scientists have now identified aromatic rice from Bangladesh that has far lower arsenic concentrations than found in non-aromatic rice.

13 Feb 2013

Medical Condition News

Traumatic brain injury investigational treatment from BHR Pharma receives EMA orphan medicinal product designation

Threat vigilance can protect soldiers against PTSD

Theradiag’s new biotherapy monitoring kits receive CE mark approval

Novel approach uses adult stem cells to save sight of diabetes sufferers

Link between Jagged-1 protein and bone formation

Study identifies and discusses key factors that lead to obesity in pregnant women

FDA grants orphan drug status to Lentigen’s LG631-CD34 for treatment of glioblastoma multiforme

Mindfulness practitioners gain enhanced control over sensory cortical alpha rhythms

New paper advances scientific understanding of glycoproteins’ structure and function

Triple-negative breast cancers more biologically diverse than previously believed

DBS can lead to long-term improvement in patients with neuropathic pain

FDA grants final approval to Breckenridge’s Pioglitazone Hydrochloride ANDA

TP PCR methodology may help streamline genetic testing for Huntington's

FDA allows Scioderm’s SD-101 IND application for Epidermolysis Bullosa to proceed

CATT study clarifies value of genetic testing for age-related macular degeneration

Examining politics of reaching NCD targets

Meridian receives ADA's Certificate of Education Recognition for diabetes education program

Researchers investigate new avenue of treatment to help boost poor pancreatic cancer survival rates

Ability to tune gene activity will permit refined research for drug resistance, cancer

Scientists identify aromatic rice with very low arsenic content

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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