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Researchers identify and test first blood-based circulating miRNA biomarkers for Parkinson's

Parkinson's disease (PD) is a progressive neurological condition. At present, it is usually diagnosed only when motor features are present. Hence, there is a need to develop objective and measurable biomarkers to improve PD diagnostics during its earlier stage, prior to its motor onset. In this pilot study, researchers identified and tested the first blood-based circulating microRNA (miRNA) biomarkers for PD.

21 Jan 2013

G-quadruplexes also exist within the human genome

In 1953, Cambridge researchers Watson and Crick published a paper describing the interweaving 'double helix' DNA structure - the chemical code for all life.

21 Jan 2013

New study: Loneliness can harm overall health

New research links loneliness to a number of dysfunctional immune responses, suggesting that being lonely has the potential to harm overall health.

20 Jan 2013

FDA to step up evaluation of metal hip implants, other devices

The Food and Drug Administration is studying whether several medical devices already on the market, such as electroconvulsive therapy devices for depression and emergency defibrillators, require additional evidence to prove they're safe.

19 Jan 2013

New review examines role of nutrition in sarcopenia

Sarcopenia, or the gradual loss of muscle mass, is a common consequence of ageing, and poses a significant risk factor for disability in older adults. As muscle strength plays an important role in the tendency to fall, sarcopenia leads to an increased risk of fractures and other injuries.

19 Jan 2013

Having 2 attending physicians during spinal surgeries can benefit patients in multiple ways

Two heads are better than one, as the saying goes - and a new study by a duo at the University of California, San Francisco (UCSF) demonstrates how having two attending surgeons in the operating room during spinal surgeries can benefit patients in multiple ways.

19 Jan 2013

Stage IV cancer cells even more susceptible to grape seed extract than stage II

When the going gets tough, grape seed extract gets going: A University of Colorado Cancer Center study recently published in the journal Cancer Letters shows that the more advanced are colorectal cancer cells, the more GSE inhibits their growth and survival. On the other end of the disease spectrum, GSE leaves healthy cells alone entirely.

19 Jan 2013

Checklists can help surgical teams perform better during emergencies

When doctors, nurses and other hospital operating room staff follow a written safety checklist to respond when a patient experiences cardiac arrest, severe allergic reaction, bleeding followed by an irregular heart beat or other crisis during surgery, they are nearly 75 percent less likely to miss a critical clinical step, according to a new study funded by the U.S. Department of Health and Human Services' Agency for Healthcare Research and Quality.

19 Jan 2013

EMA adopts positive opinion for Pfizer’s bosutinib conditional approval in the EU

Pfizer Inc. announced today that the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion regarding the conditional marketing authorization of bosutinib in the European Union for the treatment of adult patients with chronic phase (CP), accelerated phase (AP), and blast phase (BP) Philadelphia chromosome positive chronic myelogenous leukemia previously treated with one or more tyrosine kinase inhibitor(s) (TKIs) and for whom imatinib, nilotinib and dasatinib are not considered appropriate treatment options.

19 Jan 2013

St. Jude Medical’s AMPLATZER Amulet device receives European CE Mark approval

St. Jude Medical, Inc., a global medical device company, today announced European CE Mark approval of its AMPLATZER Amulet Left Atrial Appendage Occluder.

19 Jan 2013

WSU researcher to help determine success of Txt4health diabetes intervention program

A Wayne State University researcher has received a combined $36,000 in grants from the Southeastern Michigan Health Association and Greater Cincinnati HealthBridge, Inc. to help determine the success of a Type 2 diabetes intervention program currently being piloted in southeast Michigan, greater Cincinnati and New Orleans.

19 Jan 2013

Intestinal bacteria can produce biochemicals and hormones that stop development of diabetes

All humans have enormous numbers of bacteria and other micro-organisms (10 to 14) in the lower intestine. In fact our bodies contain about ten times more bacteria than our own cells and these tiny passengers are extremely important for our health. They help us digest our food and provide us with energy and vitamins.

19 Jan 2013

New method may help predict response to chemotherapy for bowel cancer

Scientists at the Royal College of Surgeons in Ireland (RCSI) and Beaumont Hospital have developed a new method of predicting which patients with bowel (colorectal) cancer will respond effectively to chemotherapy. The results of this study are published in the current issue of the prestigious Cancer Research journal.

19 Jan 2013

Cancer Targets & Therapeutics Conference to take place from Feb. 25-26 in Las Vegas

With the rapid progression of molecular biology and genetics, and the subsequent emergence of many new targets, emerging targets & therapeutics provides new opportunities for the prevention and treatment of several major disease systems.

19 Jan 2013

Possible connection between mitochondrial CYP2D6 and Parkinson's

With a new insight into a model of Parkinson's disease, researchers from the University of Pennsylvania School of Veterinary Medicine have identified a novel target for mitigating some of the disease's toll on the brain.

19 Jan 2013

NSU to host conference on neuro immune conditions

Nova Southeastern University (NSU) will be hosting a conference on Saturday, Jan. 26 about the upcoming opening of the NSU College of Osteopathic Medicine's Institute for Neuro Immune Medicine.

19 Jan 2013

FDA approves Allergan’s BOTOX to treat overactive bladder

Allergan, Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved BOTOX (onabotulinumtoxinA) for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency and frequency in adults who have had an inadequate response to or are intolerant of an anticholinergic medication.

19 Jan 2013

New model of tau pathology spread

Brain diseases associated with the misformed protein tau, including Alzheimer's disease and frontotemporal lobar degeneration with tau pathologies, are characterized by neurofibrillary tangles (NFTs) comprised of pathological tau filaments.

19 Jan 2013

Incidence of melanoma continues to rise in both men and women: ACS

The American Cancer Society's 2013 Cancer Statistics report found that the incidence of melanoma continues to rise in both men and women. This is particularly concerning because skin cancer can often be easily prevented and detected.

19 Jan 2013

Substance abuse negatively affects sexual performance in men even after years of abstinence

Researchers at the University of Granada, Spain, and Santo Tomas University in Colombia have found that drug abuse negatively affects sexual performance in men even after years of abstinence. This finding contradicts other studies reporting that men spontaneously recovered their normal sexual performance at three weeks after quitting substance abuse.

19 Jan 2013