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Key link between stem cell factors that fuel ovarian cancer's growth and patient prognosis

Researchers at Yale School of Medicine have identified a key link between stem cell factors that fuel ovarian cancer's growth and patient prognosis. The study, which paves the way for developing novel targeted ovarian cancer therapies, is published online in the current issue of Cell Cycle.

9 Jan 2013

Tunisian women more likely to suffer from obesity than male compatriots

Men and women in Tunisia are not equal before the scales. Tunisian women are three times as likely to suffer from obesity as their male compatriots.

9 Jan 2013

Scientists wrestle to understand why Huntington's can produce variable symptoms

Scientists have wrestled to understand why Huntington's disease, which is caused by a single gene mutation, can produce such variable symptoms. An authoritative review by a group of leading experts summarizes the progress relating cell loss in the striatum and cerebral cortex to symptom profile in Huntington's disease, suggesting a possible direction for developing targeted therapies.

9 Jan 2013

Dopamine-related drug exposure, Parkinson's increase risk of impulse control problems

Parkinson's disease itself does not increase the risk of impulse control problems such as compulsive gambling and shopping that have been seen in people taking certain drugs for Parkinson's disease, according to new research published in the January 8, 2013, print issue of Neurology, the medical journal of the American Academy of Neurology.

9 Jan 2013

Oramed files IND with FDA to begin ORMD-0801 Phase 2 trial for type 2 diabetes

Oramed Pharmaceuticals Inc., a developer of oral drug delivery systems, announced today that it has filed an Investigational New Drug (IND) application with the U.S. Food and Drug Administration (FDA) to begin a Phase 2 clinical trial of its orally ingested insulin candidate, ORMD-0801.

9 Jan 2013

Sublingual immunotherapy can effectively treat peanut allergy

Peanuts are one of the most common triggers of severe food-induced allergic reactions, which can be fatal, and the prevalence of peanut allergy is increasing. However, there is currently no clinical treatment available for peanut allergy other than strict dietary elimination and, in cases of accidental ingestion, injections of epinephrine.

9 Jan 2013

Beta blockers can reduce risk of Alzheimer's, other types of dementia

People taking the blood pressure drugs called beta blockers may be less likely to have changes in the brain that can be signs of Alzheimer's disease and other types of dementia, according to a study released today that will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013.

9 Jan 2013

Orexigen reports progress with FDA on faster path to Contrave NDA resubmission

Orexigen Therapeutics, Inc., a biopharmaceutical company focused on the treatment of obesity, today announced progress with the United States Food and Drug Administration (FDA) on a faster path to resubmission of the Contrave (naltrexone SR / bupropion SR) New Drug Application (NDA).

9 Jan 2013

Scientists define structure of α-catenin protein

Scientists know that cells in all higher organisms cells need to bind to each other for the development, architecture, maintenance and function of tissues. Mysteries have remained, however, about exactly how cells manage this feat.

9 Jan 2013

Insect research yields insights for muscle control and nerve disorders in mammals

Working with fruit flies, Johns Hopkins scientists have decoded the activity of protein signals that let certain nerve cells know when and where to branch so that they reach and connect to their correct muscle targets. The proteins' mammalian counterparts are known to have signaling roles in immunity, nervous system and heart development, and tumor progression, suggesting broad implications for human disease research.

9 Jan 2013

Link between IRGM gene and composition of human gastrointestinal bacteria

New research led by the Karolinska Institutet, Sweden and the University of Glasgow, Scotland, has identified a link between a human gene and the composition of human gastrointestinal bacteria.

9 Jan 2013

Researchers deploy sensitive brain-testing methods on injured high school athletes

The ability to focus and switch tasks readily amid distractions was compromised for up to two months following brain concussions suffered by high school athletes, according to a study at the University of Oregon.

9 Jan 2013

People from low socio-economic positions in Britain eat more salt than the well off

People from low socio-economic positions in Britain eat more salt than the well off, irrespective of where they live, states a paper led by Warwick Medical School published on Tuesday in the BMJ Open journal .

9 Jan 2013

Study demonstrates effects of obesity on 'Taupathies'

In France, more than 860,000 people suffer from Alzheimer's disease and related disorders, making them the largest cause of age-related loss of intellectual function. Cognitive impairments observed in Alzheimer's disease result from the accumulation of abnormal tau proteins in nerve cells undergoing degeneration . We know that obesity, a major risk factor in the development of insulin resistance and type 2 diabetes, increases the risk of dementia during the aging process.

9 Jan 2013

ISCT selects Elsevier to publish Cytotherapy

Elsevier, a world-leading provider of scientific, technical and medical information products and services, is pleased to announce that the International Society for Cellular Therapy (ISCT) has selected Elsevier to publish Cytotherapy: The Journal of Cell Therapy effective January 2013.

8 Jan 2013

Esperion reports positive results from ETC-1002 Phase 2 clinical trial on type 2 diabetes

Esperion Therapeutics, the leading developer of small molecule therapies for the treatment of cardiometabolic disorders, today announced positive results of a recently completed Phase 2 clinical trial of ETC-1002 in patients with type 2 diabetes with LDL-C lowering of up to 43% compared to placebo.

8 Jan 2013

Thoratec to start REVIVE-IT study using HeartMate II Left Ventricular Assist System

Thoratec Corporation, a world leader in device-based mechanical circulatory support therapies to save, support and restore failing hearts, today announced that the U.S. Food and Drug Administration has granted an Investigational Device Exemption to commence the REVIVE-IT study utilizing the HeartMate II Left Ventricular Assist System.

8 Jan 2013

FDA approves use of iCAD's PowerLook AMP with Philips MicroDose Digital Mammography System

iCAD, Inc., an industry-leading provider of advanced image analysis, workflow solutions and radiation therapy for the early identification and treatment of cancer, today announced approval by the U.S. Food and Drug Administration for use of the company's next generation mammography computer-aided detection platform, PowerLook Advanced Mammography Platform, with Digital CAD for Philips' MicroDose Full-Field Digital Mammography System.

8 Jan 2013

Spectrum Pharmaceuticals reveals positive RenaZorb Phase 1 clinical trial results

Spectrum Pharmaceuticals, a biotechnology company with fully integrated commercial and drug development operations with a primary focus in hematology and oncology, today announced positive, statistically significant data from the Company's Phase 1 clinical trial evaluating the safety and tolerability of RenaZorb (also referred to as SPI-014) in healthy volunteers.

8 Jan 2013

Seven scientists named 2013 recipients of Damon Runyon-Rachleff Innovation Award

The Damon Runyon Cancer Research Foundation announced that seven scientists with novel approaches to fighting cancer have been named 2013 recipients of the Damon Runyon-Rachleff Innovation Award.

8 Jan 2013

Medical Condition News

Key link between stem cell factors that fuel ovarian cancer's growth and patient prognosis

Tunisian women more likely to suffer from obesity than male compatriots

Scientists wrestle to understand why Huntington's can produce variable symptoms

Dopamine-related drug exposure, Parkinson's increase risk of impulse control problems

Oramed files IND with FDA to begin ORMD-0801 Phase 2 trial for type 2 diabetes

Sublingual immunotherapy can effectively treat peanut allergy

Beta blockers can reduce risk of Alzheimer's, other types of dementia

Orexigen reports progress with FDA on faster path to Contrave NDA resubmission

Scientists define structure of α-catenin protein

Insect research yields insights for muscle control and nerve disorders in mammals

Link between IRGM gene and composition of human gastrointestinal bacteria

Researchers deploy sensitive brain-testing methods on injured high school athletes

People from low socio-economic positions in Britain eat more salt than the well off

Study demonstrates effects of obesity on 'Taupathies'

ISCT selects Elsevier to publish Cytotherapy

Esperion reports positive results from ETC-1002 Phase 2 clinical trial on type 2 diabetes

Thoratec to start REVIVE-IT study using HeartMate II Left Ventricular Assist System

FDA approves use of iCAD's PowerLook AMP with Philips MicroDose Digital Mammography System

Spectrum Pharmaceuticals reveals positive RenaZorb Phase 1 clinical trial results

Seven scientists named 2013 recipients of Damon Runyon-Rachleff Innovation Award

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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