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Celgene to discontinue treatment with REVLIMID in phase III ORIGIN trial

Celgene Corporation today announced that after consultation with the U.S. Food and Drug Administration Celgene will discontinue treatment with REVLIMID (lenalidomide) in the open-label, phase III ORIGIN trial, which enrolled 450 patients in over 100 sites in 26 countries.

18 Jul 2013

Inovio's electroporation technology enhances ability of DNA therapy to stimulate blood vessel growth

Inovio Pharmaceuticals, Inc. announced today that the use of its proprietary electroporation technology significantly enhanced the ability of a DNA therapy to stimulate blood vessel growth, which may be beneficial for the treatment of critical limb ischemia and other forms of peripheral arterial disease.

18 Jul 2013

Human filariasis research: an interview with Professor Mark Taylor, Liverpool School of Tropical Medicine

Filariasis refers to a group of diseases caused by parasitic worms, which are transmitted by blood feeding insects. Two species infect the lymphatic and blood systems causing lymphatic filariasis, which in some people can lead to gross swelling of the limbs and 'elephantiasis'.

18 Jul 2013

CHOP-led research increases numbers of patients who could be treated with gene therapy

Gene therapy researchers have produced a bioengineered decoy that fools the immune system and prevents it from mistakenly defeating the benefits delivered by a corrective gene.

18 Jul 2013

Transition Therapeutics' ELND005 receives Fast Track Designation from FDA

Transition Therapeutics Inc. announced that the US Food and Drug Administration has granted Fast Track Designation to the development program for ELND005 which was submitted for the treatment of Neuropsychiatric Symptoms in Alzheimer's disease.

18 Jul 2013

Scientists develop iKnife that helps surgeons identify cancerous tissues

Scientists have developed an "intelligent knife" that can tell surgeons immediately whether the tissue they are cutting is cancerous or not.

18 Jul 2013

Study shows positive impact of using music as personal coping method for cancer patients

Very few treatments or therapies endured by cancer patients can be described as pleasant, but a study published in Arts & Health shows the positive impact of using music as a personal coping method when faced with the disease.

18 Jul 2013

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

Scientists at the University of Massachusetts Medical School are the first to establish that a naturally occurring X chromosome "off switch" can be rerouted to neutralize the extra chromosome responsible for trisomy 21, also known as Down syndrome, a genetic disorder characterized by cognitive impairment.

18 Jul 2013

Creating, promoting foods containing angiogenesis is the new frontier in dietary health

Creating and promoting foods that contain natural inhibitors of unhealthy angiogenesis - the formation of blood vessels that feed and promote disease, obesity and inflammation - is the "new frontier in dietary health," according to a presentation at the 2013 Institute of Food Technologists Annual Meeting & Food Expo- in Chicago.

18 Jul 2013

Both milky spots and fat cells in omentum promote ovarian cancer metastases

Cancer researchers have wondered why ovarian cancer cells are so attracted to the abdominal cavity, especially the omentum, with the hope that such an understanding could lead to better disease management or even prevention.

18 Jul 2013

Virginia Commonwealth University receives $1.8M grant to study biology of allergic disease

The National Institutes of Health has awarded Virginia Commonwealth University a grant totaling $1.8 million to study the biology of allergic disease - work which may one day point researchers to the development of therapies to fight asthma, allergy and inflammatory conditions such as rheumatoid arthritis, multiple sclerosis and heart disease.

18 Jul 2013

TSRI scientists study 3-D structure of glucagon receptor for treatment of diabetes

The study is reported on July 17, 2013, in an advance online edition of the journal Nature, alongside a British laboratory's structural study of another member of the same class of receptors-known as "class B" G protein-coupled receptors (GPCRs).

18 Jul 2013

Spectrum researchers closer to predicting patients’ risk for heart attacks

We may be closer to predicting who is at risk for a heart attack, according to a recently published Spectrum Health study. Researchers with Spectrum Health's Frederik Meijer Heart & Vascular Institute used new imaging technology on patients being treated for heart attacks.

18 Jul 2013

Study may allow more patients to benefit from transcatheter aortic valve replacement

The Society of Thoracic Surgeons (STS) has launched an investigational study with the American College of Cardiology (ACC) that may allow more patients to benefit from transcatheter aortic valve replacement (TAVR), a minimally invasive procedure that delivers a replacement heart valve via a catheter.

18 Jul 2013

AbGenomics raises $9.6M for advancing therapeutic antibodies for autoimmune diseases, cancers

AbGenomics International announced today that it has raised $9.6 million in current financing round.

18 Jul 2013

Single dose of methylphenidate can reduce risk of falls among elderly adults

Ben-Gurion University of the Negev researchers have discovered that a single dose of methylphenidate, used to treat Attention Deficit Hyperactivity Disorder and narcolepsy, helps to improve balance control during walking, hence reducing the risk of falls among elderly adults.

18 Jul 2013

Exposure to PFC may increase risk of mild hypothyroidism in women

Exposure to perfluorinated chemicals is linked to changes in thyroid function and may raise the risk of mild hypothyroidism in women, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

18 Jul 2013

Research: Young adults who are more outgoing are happier in later life

Research from the University of Southampton has shown that young adults, who are more outgoing or more emotionally stable, are happier in later life than their more introverted or less emotionally stable peers.

18 Jul 2013

Novel way to fine-tune activity of cells' protein-disposing machinery with cancer-fighting effects

Molecular biologists in the School of Medicine at The University of Texas Health Science Center San Antonio have found a novel way to fine-tune the activity of cells' protein-disposing machinery, with potentially cancer-fighting effects.

18 Jul 2013

Drug that spurs cancer cells to self-destruct is on road to human clinical trials

Thanks to a new $2 million investment, a drug that spurs cancer cells to self-destruct while sparing healthy cells is on the road to human clinical trials. The compound, known as PAC-1, has so far proven safe and has promising anti-cancer effects in cell culture, in mouse models of cancer and in pet dogs with spontaneously occurring lymphomas and osteosarcomas.

18 Jul 2013

Medical Condition News

Celgene to discontinue treatment with REVLIMID in phase III ORIGIN trial

Inovio's electroporation technology enhances ability of DNA therapy to stimulate blood vessel growth

Human filariasis research: an interview with Professor Mark Taylor, Liverpool School of Tropical Medicine

CHOP-led research increases numbers of patients who could be treated with gene therapy

Transition Therapeutics' ELND005 receives Fast Track Designation from FDA

Scientists develop iKnife that helps surgeons identify cancerous tissues

Study shows positive impact of using music as personal coping method for cancer patients

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

Creating, promoting foods containing angiogenesis is the new frontier in dietary health

Both milky spots and fat cells in omentum promote ovarian cancer metastases

Virginia Commonwealth University receives $1.8M grant to study biology of allergic disease

TSRI scientists study 3-D structure of glucagon receptor for treatment of diabetes

Spectrum researchers closer to predicting patients’ risk for heart attacks

Study may allow more patients to benefit from transcatheter aortic valve replacement

AbGenomics raises $9.6M for advancing therapeutic antibodies for autoimmune diseases, cancers

Single dose of methylphenidate can reduce risk of falls among elderly adults

Exposure to PFC may increase risk of mild hypothyroidism in women

Research: Young adults who are more outgoing are happier in later life

Novel way to fine-tune activity of cells' protein-disposing machinery with cancer-fighting effects

Drug that spurs cancer cells to self-destruct is on road to human clinical trials

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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