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Mutated Nesprin4 protein prevents hearing

Because half of all instances of hearing loss are linked to genetic mutations, advanced gene research is an invaluable tool for uncovering causes of deafness - and one of the biggest hopes for the development of new therapies. Now Prof. Karen Avraham of the Sackler Faculty of Medicine at Tel Aviv University has discovered a significant mutation in a LINC family protein - part of the cells of the inner ear - that could lead to new treatments for hearing disorders.

29 Jan 2013

Bone Medical announces initial findings from BN006 proof of concept RA study

Bone Medical Ltd, a biopharmaceutical company focused on the development of new medicines for musculoskeletal diseases, today announced initial findings from a proof of concept study of BN006, a treatment that it is developing for Rheumatoid Arthritis (RA) based on its Mozaic™ peptide discovery technology.

29 Jan 2013

Regular deep-fried food consumption may increase risk of prostate cancer

Regular consumption of deep-fried foods such as French fries, fried chicken and doughnuts is associated with an increased risk of prostate cancer, and the effect appears to be slightly stronger with regard to more aggressive forms of the disease, according to a study by investigators at Fred Hutchinson Cancer Research Center.

29 Jan 2013

Abbott Vascular designates Montreal Heart Institute as a Center of Excellence

The Montreal Heart Institute has just been designated as a Center of Excellence by Abbott Vascular for the percutaneous treatment of mitral valve failure with their MitraClip system. The MHI has therefore become a reference centre for this procedure for all hospitals across Canada and many other hospitals in North America.

29 Jan 2013

Mayo Clinic study: Cardiac disease may increase risk of mild cognitive impairment

Cardiac disease is associated with increased risk of mild cognitive impairment such as problems with language, thinking and judgment -- particularly among women with heart disease, a Mayo Clinic study shows. Known as nonamnestic because it doesn't include memory loss, this type of mild cognitive impairment may be a precursor to vascular and other non-Alzheimer's dementias, according to the findings published online Monday in JAMA Neurology.

29 Jan 2013

Reprogramming eye cells that enable night vision may one day treat retinitis pigmentosa

Doctors may one day treat some forms of blindness by altering the genetic program of the light-sensing cells of the eye, according to scientists at Washington University School of Medicine in St. Louis.

29 Jan 2013

DRCRF announces recipients of Nov. 2012 Damon Runyon Fellows

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 15 new Damon Runyon Fellows at its fall Fellowship Award Committee review.

29 Jan 2013

GENIEUR teams aim to understand causes and treatment of irritable bowel syndrome

Europe-wide network GENIEUR including researchers from Sahlgrenska Academy, University of Gothenburg, Sweden, and Karolinska Institutet, Sweden, launch program for understanding the causes and improving the diagnosis and treatment of irritable bowel syndrome

29 Jan 2013

Benefits of GPS for people with dementia

As part of the norwegian research project "Trygge Spor", more than fifty dementia sufferers have been using GPS for periods varying from several weeks to up to a year. The results show that localisation technology helps achieve an increased sense of security, freedom and quality of life, both for sufferers and their next of kin.

29 Jan 2013

MAKOplasty Hip may benefit people with degenerative joint disease

The hip is one of your body's largest weight-bearing joints and millions of Americans are suffering with hip pain. Adventist Medical Center is the first and only hospital in Oregon, providing people suffering from hip pain, an option of robotic assisted surgery. Thanks to the collaboration between orthopedic surgeons and a robot, patients can now experience less pain and quicker recovery times.

29 Jan 2013

Transcendental Meditation technique reduces PTSD symptoms in U.S. Marines

U.S. Marines and other active-duty military personnel who suffer from post-traumatic stress disorder (PTSD) are finding relief through a simple meditation technique known as the Transcendental Meditation (TM) technique.

29 Jan 2013

Minimally invasive islet transplantation reverses progression of atherosclerosis in type 1 diabetics

Minimally invasive islet transplantation for patients with type 1 diabetes achieves insulin independence and reverses the progression of atherosclerosis in the first few years after transplant, according to a University of Illinois at Chicago study.

29 Jan 2013

New, preference-based navigation intervention improves screening rates for colon cancer

A mailing or phone call to help patients get screened for colorectal cancer significantly increases their chances of actually getting tested, according to a study published in the January issue of Cancer Epidemiology, Biomarkers and Prevention by researchers at the Kimmel Cancer Center at Jefferson.

29 Jan 2013

Meridian reports positive pre-IND meeting with FDA for ML061

Buffalo Grove, Illinois-based specialty-oncology drug development company, Meridian Laboratories, Inc (Meridian) held a Type B Pre-Investigational New Drug (pre-IND) meeting with the FDA Center for Drug Evaluation Research, Division of Oncology Products on Wednesday January 23, 2013 to discuss its plan to commence clinical development of ML061, Meridian's lead product, as a treatment for various types of cancer.

29 Jan 2013

Stem cells from bone marrow or fat improve recovery after stroke in rats

Stem cells from bone marrow or fat improve recovery after stroke in rats, finds a study published in BioMed Central's open access journal Stem Cell Research & Therapy. Treatment with stem cells improved the amount of brain and nerve repair and the ability of the animals to complete behavioural tasks.

29 Jan 2013

Researchers unveil first maturation-based ‘disease in a dish’ model for ARVD/C

Most patients with an inherited heart condition known as arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) don't know they have a problem until they're in their early 20s. The lack of symptoms at younger ages makes it very difficult for researchers to study how ARVD/C evolves or to develop treatments. A new stem cell-based technology created by 2012 Nobel Prize winner Shinya Yamanaka, M.D., Ph.D., helps solve this problem.

29 Jan 2013

Sanofi announces availability of Auvi-Q in U.S. retail pharmacies

Sanofi announced today that Auvi-Q (epinephrine injection, USP) is now available in U.S. retail pharmacies nationwide with a prescription from a healthcare provider.

29 Jan 2013

IOF-ESCEO Pre-Clinical Symposium to be held on April 18 in Rome, Italy

Investigators with an interest in pre-clinical and translational musculoskeletal research are invited to attend the 3rd IOF-ESCEO Pre-Clinical Symposium to be held on April 18, in Rome, Italy.

29 Jan 2013

Emotional stress can reduce prostate cancer drugs’ effectiveness

Not surprisingly, a cancer diagnosis creates stress. And patients with prostate cancer show higher levels of anxiety compared to other cancer patients. A new study by researchers at Wake Forest Baptist Medical Center indicates that stress is not just an emotional side effect of the diagnosis; it also can reduce the effectiveness of prostate cancer drugs and accelerate the development of prostate cancer.

29 Jan 2013

UAB dietitian suggests five foods for healthier eating

With the hectic hustle and bustle of daily life — managing family, career, home and more — it is no wonder that creativity in the kitchen can fall to the wayside. To help people get out of a food rut and eat healthier this year, a dietitian from the University of Alabama at Birmingham (UAB) suggests adding five foods to the grocery cart.

29 Jan 2013