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Study sheds new light on why certain people are more likely to suffer from RA

University of Michigan research sheds new light on why certain people are more likely to suffer from rheumatoid arthritis - paving the way to explore new treatments for both arthritis and other autoimmune diseases.

28 Jan 2013

AstraZeneca, Orexo partner on OX-CLI preclinical program to treat respiratory diseases

Orexo AB announced today that the company has entered into an agreement with AstraZeneca regarding OX-CLI, a preclinical program for a potential novel treatment of respiratory diseases.

28 Jan 2013

TSRI scientists to identify, test and develop drug candidates for several neurodegenerative disorders

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded approximately $1.2 million from the U.S. National Institute of General Medical Sciences of the National Institutes of Health to identify, test and develop a series of drug candidates for a number of diseases, including rheumatoid arthritis, heart disease and several neurodegenerative disorders.

28 Jan 2013

IRHOM2-targeted drugs can effectively treat patients with rheumatoid arthritis

Researchers at Hospital for Special Surgery have identified a potential new target for drugs to treat patients with rheumatoid arthritis (RA), a protein known as IRHOM2. The finding could provide an effective and potentially less toxic alternative therapy to tumor necrosis factor-alpha blockers (TNF-blockers), the mainstay of treatment for rheumatoid arthritis, and could help patients who do not respond to this treatment. Efforts to develop drugs that hone in on this new target are underway.

28 Jan 2013

New AngioSculpt catheters from AngioScore can treat peripheral artery disease below the knee

AngioScore, Inc., a developer of novel angioplasty catheters for use in the treatment of cardiovascular disease, today announced the launch of its new 100 mm length AngioSculpt PTA Scoring Balloon Catheters for the treatment of peripheral artery disease (PAD) below the knee (BTK).

28 Jan 2013

FDA approves Takeda’s NESINA, OSENI and KAZANO for treatment of type 2 diabetes

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals U.S.A., Inc. today announced that the United States (U.S.) Food and Drug Administration (FDA) has approved NESINA (alogliptin) and the fixed-dose combination (FDC) therapies OSENI (alogliptin and pioglitazone) and KAZANO (alogliptin and metformin HCl) for the treatment of type 2 diabetes in adults as adjuncts to diet and exercise.

28 Jan 2013

Results from Amgen’s Neulasta plus bevacizumab Phase 3 trial on colorectal cancer

Amgen announced today results from Pegfilgrastim and Anti-VEGF Evaluation Study (PAVES), a Phase 3 trial which evaluated Neulasta (pegfilgrastim) in 845 patients receiving FOLFOX or FOLFIRI and bevacizumab for the first-line treatment of locally-advanced or metastatic colorectal cancer.

28 Jan 2013

Telomerase gene mutation immortalizes deadly skin cancer

About ten percent of all cases of malignant melanoma are familial cases. The genome of affected families tells scientists a lot about how the disease develops. Prof. Dr. Rajiv Kumar of the German Cancer Research Center together with Prof. Dr. Dirk Schadendorf from Essen University Hospital studied a family where 14 family members were affected by malignant melanoma.

28 Jan 2013

Research roundup: Does higher Rx drug spending lower Medicare costs?; Price transparency doesn't affect radiological decisions

Researchers aimed to find a relationship between geographic variation in Medicare Part D spending and medication-taking behavior among patients with diabetes or heart failure.

28 Jan 2013

Interim results from Seattle Genetics’ ASG-5ME phase I trial on metastatic PDA

Seattle Genetics, Inc. today presented interim results from a phase I clinical trial evaluating ASG-5ME for the treatment of metastatic pancreatic ductal adenocarcinoma (PDA) at the American Society of Clinical Oncology (ASCO) 2013 Gastrointestinal Cancers Symposium being held January 24-26, 2013 in San Francisco, CA.

28 Jan 2013

Takeda receives FDA approval for Nesina, Kazano and Oseni to treat type 2 diabetes

The U.S. Food and Drug Administration today approved three new related products for use with diet and exercise to improve blood sugar control in adults with type 2 diabetes: Nesina (alogliptin) tablets, Kazano (alogliptin and metformin hydrochloride) tablets, and Oseni (alogliptin and pioglitazone) tablets.

28 Jan 2013

Reducing the level of mutant p53 gene increases susceptibility to cancer treatment

Scientists from the National Cancer Centre Singapore (NCCS) have discovered the workings of the gene that has been hindering treatment response in cancer patients. This discovery was made after 5 years of studying the mutant form of the p53 gene, the major tumor suppressor in humans, which is generally found mutated in over 50% of all type of human cancers.

27 Jan 2013

New research on flavonoids and nutritional health in older adults from JONGG

Routledge Journals is pleased to announce a Special Issue from the Journal of Nutrition in Gerontology and Geriatrics focusing on the impact of flavonoids on the nutritional health of older adults.

27 Jan 2013

Short-term use of folic acid supplements unlikely to increase cancer risk

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25 Jan 2013

Tailored treatments and PSA screenings required to improve health outcomes in Ghana

Infectious diseases in Ghana tend to capture the most attention, but a quiet crisis may soon take over as the country's most threatening epidemic: cancer.

25 Jan 2013

Ohio State's Wexner Medical Center performs DBS surgery on Alzheimer's patient

During a five-hour surgery last October at The Ohio State University Wexner Medical Center, Kathy Sanford became the first Alzheimer's patient in the United States to have a pacemaker implanted in her brain.

25 Jan 2013

Researchers study innovative stem cell drug for treating localized cartilage damage

Rush University Medical Center is conducting the nation's first clinical study of an innovative stem cell drug, Cartistem, to repair knee cartilage damaged by aging, trauma or degenerative diseases such as osteoarthritis.

25 Jan 2013

Findings could help develop targeted exercise for obese women with Type 2 diabetes

More than one-third of Americans are obese, and these individuals often experience accompanying health issues, such as Type 2 diabetes and cardiovascular problems. In response to the so-called "obesity epidemic," many medical professionals have suggested ways to improve the health outcomes of obese individuals through diet and exercise.

25 Jan 2013

African-American women who reported childhood abuse had greater risk of uterine fibroids

According to a new study from the Slone Epidemiology Center (SEC) at Boston University, African-American women who reported sexual or physical abuse before age 11 had a greater risk of uterine fibroids in adulthood compared with women who had no such abuse history.

25 Jan 2013

Researchers identify cancer-associated mutations

Two new mutations that collectively occur in 71 percent of malignant melanoma tumors have been discovered in what scientists call the "dark matter" of the cancer genome, where cancer-related mutations haven't been previously found.

25 Jan 2013

Medical Condition News

Study sheds new light on why certain people are more likely to suffer from RA

AstraZeneca, Orexo partner on OX-CLI preclinical program to treat respiratory diseases

TSRI scientists to identify, test and develop drug candidates for several neurodegenerative disorders

IRHOM2-targeted drugs can effectively treat patients with rheumatoid arthritis

New AngioSculpt catheters from AngioScore can treat peripheral artery disease below the knee

FDA approves Takeda’s NESINA, OSENI and KAZANO for treatment of type 2 diabetes

Results from Amgen’s Neulasta plus bevacizumab Phase 3 trial on colorectal cancer

Telomerase gene mutation immortalizes deadly skin cancer

Research roundup: Does higher Rx drug spending lower Medicare costs?; Price transparency doesn't affect radiological decisions

Interim results from Seattle Genetics’ ASG-5ME phase I trial on metastatic PDA

Takeda receives FDA approval for Nesina, Kazano and Oseni to treat type 2 diabetes

Reducing the level of mutant p53 gene increases susceptibility to cancer treatment

New research on flavonoids and nutritional health in older adults from JONGG

Short-term use of folic acid supplements unlikely to increase cancer risk

Tailored treatments and PSA screenings required to improve health outcomes in Ghana

Ohio State's Wexner Medical Center performs DBS surgery on Alzheimer's patient

Researchers study innovative stem cell drug for treating localized cartilage damage

Findings could help develop targeted exercise for obese women with Type 2 diabetes

African-American women who reported childhood abuse had greater risk of uterine fibroids

Researchers identify cancer-associated mutations

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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