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Imatinib can relieve and slow down progression of multiple sclerosis

A drug that is currently used for cancer can relieve and slow down the progression of the autoimmune disease multiple sclerosis (MS) in rats, according to a new study published in PLOS ONE.

21 Feb 2013

Microbubble-ultrasound method improves cardiac output after heart attack

Scientists from the Bonn University Hospital successfully tested a method in mice allowing the morphological and functional sequelae of a myocardial infarction to be reduced. Tiny gas bubbles are made to oscillate within the heart via focused ultrasound - this improves microcirculation and decreases the size of the scar tissue. The results show that the mice, following myocardial infarction, have improved cardiac output as a result of this method, as compared to untreated animals.

21 Feb 2013

Patients with Barrett's esophagus benefit from endoscope-based therapies

According to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, patients with Barrett's esophagus and early or pre-cancerous cells have been shown to significantly benefit from minimally invasive therapy delivered through an endoscope - a medical instrument used to look inside an organ or cavity in the body.

21 Feb 2013

Bariatric surgery does not lower overall health care costs linked with obesity

Bariatric surgery is a well-documented treatment for obesity that leads to considerable weight loss and health improvement, but is the surgery successful in the long run in reducing costs associated with medical care for obesity? A team of researchers from the Johns Hopkins Bloomberg School of Public Health and School of Medicine recently undertook a multi-year analysis of health insurance claims data to examine this question and found that although the procedure's success rate is well documented, it does not have a similar impact on health care costs.

21 Feb 2013

Cancer genetics pioneer, Bert Vogelstein, awarded the Breakthrough Prize in Life Sciences

Bert Vogelstein, M.D., co-director of the Ludwig Center at Johns Hopkins and a Howard Hughes Medical Institute investigator has been awarded the Breakthrough Prize in Life Sciences. He was selected for his landmark work in cancer genomics and tumor suppressor genes.

21 Feb 2013

Study looks at natural history of cervical spondylolisthesis

Follow-up data on patients with degenerative disease of the upper (cervical) spinal vertebrae show little or no evidence of worsening degeneration over time, according to a study in the February 15 issue of Spine.

21 Feb 2013

Omega-3 emulsions can decrease brain tissue damage following stroke

Triglyceride lipid emulsions rich in an omega-3 fatty acid injected within a few hours of an ischemic stroke can decrease the amount of damaged brain tissue by 50 percent or more in mice, reports a new study by researchers at Columbia University Medical Center.

21 Feb 2013

Rising epidemic of obesity in the Asia Pacific region

Over eating, sedentary lifestyles, cultural attitudes, and lack of prevention programmes are to blame for the rising epidemic of obesity in the Asia Pacific region. Overweight and obesity has quadrupled in China and societies still label people of healthy weight as poor.

21 Feb 2013

Resveratrol may protect against hearing and cognitive decline

Resveratrol, a substance found in red grapes and red wine, may have the potential to protect against hearing and cognitive decline, according to a published laboratory study from Henry Ford Hospital in Detroit.

21 Feb 2013

Tips to help reduce dry eyes

Some of the last days of winter can be among the worst for your eyes. Winter may be slowly giving way to spring, but the remaining cold days of the season can cause plenty of trouble for the eyes—trouble that is largely avoidable, says a Vanderbilt Eye Institute ophthalmologist.

21 Feb 2013

Reviewing progress on inclusion of NCDs in development goals

In a post in the BMJ Group Blogs, Katy Cooper, senior project manager at C3 Collaborating for Health, describes "what is happening around the global framework on non-communicable diseases, and how NCDs link into discussions on the successors to the Millennium Development Goals (due to expire in 2015) and the proposed new set of Sustainable Development Goals (as proposed at the Rio+20 conference in 2012)."

21 Feb 2013

Bracelet-like device with magnetic beads can control gastroesophageal reflux disease

A bracelet-like device with magnetic beads can control the chronic digestive disorder gastroesophageal reflux disease, according to a study published online today in the New England Journal of Medicine.

21 Feb 2013

U.N. report examines links between man-made chemicals, health issues

"Man-made chemicals in everyday products are likely to be at least the partial cause of a global surge in birth deformities, hormonal cancers and psychiatric diseases, a U.N.-sponsored research team reported on Tuesday," Reuters reports.

21 Feb 2013

Selenium supplements and heart disease risk: an interview with Dr Saverio Stranges, University of Warwick

Selenium is a micronutrient which has antioxidant properties by means of selenoproteins which play many important functions in the body. They actually are contained in many different foods. The amount of selenium we get from diet is closely linked to the amount of selenium in the soil.

21 Feb 2013

Ultrathin nanowire-based electrode helps capture signals from brain nerve cells

Electrodes operated into the brain are today used in research and to treat diseases such as Parkinson's. However, their use has been limited by their size. At Lund University in Sweden, researchers have, for the first time, succeeded in implanting an ultrathin nanowire-based electrode and capturing signals from the nerve cells in the brain of a laboratory animal.

21 Feb 2013

Simple interventions could reduce delirium and improve patient perceptions about sleep quality

A hospital is not the best place to get a good night's sleep, especially in a noisy intensive care unit. It's a cause for concern because studies have shown that a lack of sleep can cause patients to experience delirium-an altered mental state that may delay their recovery and lead to short and long-term confusion and memory problems.

21 Feb 2013

Article provides examples of how epigenetic drug treatments could be beneficial in treating cancers

A review article by researchers at Boston University School of Medicine (BUSM) proposes a new epigenetic hypothesis linked to tumor production and novel ideas about what causes progenitor cells to develop into cancer cells. Published in the February 2013 issue of Epigenomics, the article provides examples of how epigenetic drug treatments could be beneficial in treating cancers while also decreasing the likelihood of cancer relapse.

21 Feb 2013

Hydroxyethyl starch associated with increased risk of death and acute kidney injury

In an analysis of studies that examined critically ill patients requiring an increase in blood fluid volume, intravenous use of the fluid hydroxyethyl starch was not associated with decreased mortality, according to an article appearing in the February 20 issue of JAMA.

21 Feb 2013

BCHE gene variant predicts extent of plaque deposits in Alzheimer's

A study combining genetic data with brain imaging, designed to identify genes associated with the amyloid plaque deposits found in Alzheimer's disease patients, has not only identified the APOE gene -- long associated with development of Alzheimer's -- but has uncovered an association with a second gene, called BCHE.

21 Feb 2013

UCSD molecular biologist to receive Breakthrough Prize in Life Sciences

Napoleone Ferrara, MD, PhD, the molecular biologist credited with helping decipher how tumors grow and now senior deputy director for basic sciences at the University of California, San Diego Moores Cancer Center, was today named one of 11 recipients of the inaugural Breakthrough Prize in Life Sciences, which comes with a $3 million cash award.

21 Feb 2013