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Clinuvel submits SCENESSE MAA to EMA for treatment of erythropoietic protoporphyria

Clinuvel Pharmaceuticals Limited today announced that it has submitted a marketing authorisation application (MAA) for its first-in-class drug SCENESSE (afamelanotide 16mg implant) to the European Medicines Agency.

6 Feb 2012

CD74 molecule plays a guiding role in immune responses against diseases

University of British Columbia researchers have discovered the molecular pathway that enables receptors inside immune cells to find, and flag, fragments of pathogens trying to invade a host.

6 Feb 2012

Scientists identify genetic variant that increases risk of ischemic stroke

A genetic variant that increases the risk of a common type of stroke has been identified by scientists in a study published online in Nature Genetics today. This is one of the few genetic variants to date to be associated with risk of stroke and the discovery opens up new possibilities for treatment.

6 Feb 2012

Two molecules hold promise as a biomarker for OA

Henry Ford Hospital researchers have identified for the first time two molecules that hold promise as a biomarker for measuring cartilage damage associated with osteoarthritis.

5 Feb 2012

New stent retriever procedure safe, effective for patients with stroke

A new way of opening blocked arteries in the brain using a removable stent system in people suffering strokes brought remarkably positive results in how those patients recovered from the strokes, according to a study presented this morning at the American Stroke Association's annual conference in New Orleans.

4 Feb 2012

Two different research groups make similar advances in AD study

Two different research groups have independently made the same important discoveries on how Alzheimer's disease spreads in the brain, according to a February 2 New York Times story. The groups' findings have the potential to give us a much more sophisticated understanding of what goes wrong in Alzheimer's disease and, more importantly, what can be done to prevent or repair damage in the brain.

4 Feb 2012

Future of social robotics requires meeting the expectations of human brain

After years of existing only in fiction, social robots are finally being designed that can more closely emulate how people express themselves, interact and learn - and doing so while performing jobs like teaching social behavior to children with autism or helping stroke patients with their physical rehabilitation exercises.

4 Feb 2012

Study offers evidence that toxic forms of Alzheimer's protein spread in the brain

Tau tangles are one half of the twin hallmark pathologies of Alzheimer's disease—the half that is most closely tied to the death of neurons. A study in the February 1 PLoS One offers evidence that the toxic forms of tau that cause these tangles spread throughout the brain by moving from one neuron to the next in a pattern that tracks anatomical synaptic connections of the earliest-hit nerve cells in the brain.

4 Feb 2012

Road Hockey To Conquer Cancer to kick off sophomore campaign on Feb. 7

It's an ordinary workday, and the lunch hour at Commerce Court is bustling with people. Wait a minute! What the heck is going on? Where did those hockey sticks come from? How did those nets appear? There's a road hockey game in progress!! But what the heck is with those guys wearing jockstraps over their suits? After an extraordinary inaugural event that raised $2.4 million for cancer research at The Princess Margaret Cancer Centre and Canadian Cancer Society, Road Hockey To Conquer Cancer will kick off its sophomore campaign with a spontaneous road hockey game on Tuesday, February 7, 2012 at 12:30pm in the courtyard at Commerce Court.

4 Feb 2012

Study to determine how body weight, hormones affect bone health from childhood to adulthood

Researchers from the University of Sheffield are conducting ground-breaking research to determine how body weight and hormones affect bone health from childhood to adulthood.

4 Feb 2012

UCLA professor receives ASA's Feinberg Award for clinical stroke research

Dr. Jeffrey L. Saver, professor of neurology at the David Geffen School of Medicine at UCLA and director of the UCLA Stroke Center, received the William Feinberg Award for Excellence in Clinical Stroke at the American Stroke Association's 2012 International Stroke Conference in New Orleans on Feb. 2.

4 Feb 2012

CT-guided catheters carry t-PA to shrink clots in patients with ICH

Johns Hopkins neurologists report success with a new means of getting rid of potentially lethal blood clots in the brain safely without cutting through easily damaged brain tissue or removing large pieces of skull. The minimally invasive treatment, they report, increased the number of patients with intracerebral hemorrhage (ICH) who could function independently by 10 to 15 percent six months following the procedure.

4 Feb 2012

New approach can solve treatment-resistant problem in cancers

Free-flowing cancer cells have been mapped with unprecedented accuracy in the bloodstream of patients with prostate, breast and pancreatic cancer, using a brand new approach, in an attempt to assess and control the disease as it spreads in real time through the body, and solve the problem of predicting response and resistance to therapies.

4 Feb 2012

UTMB's international vaccine symposium to be held Feb. 7-9

An international vaccine symposium sponsored by the University of Texas Medical Branch at Galveston and scheduled for Feb. 7-9 will reflect a dramatic shift in the world of vaccinology, according to Alan Barrett, director of UTMB's Sealy Center for Vaccine Development.

4 Feb 2012

Starkey delivers gift to 235 hearing impaired children and adults from Indianapolis

With the help of a star-studded line up of football and entertainment legends, Starkey Hearing Foundation, which strives to change the social consciousness of hearing and hearing health care, delivered the gift of hearing today to 235 hearing impaired children and adults from the Indianapolis area ranging in age from 3 to 92. The event, which marked the Foundation's 3rd annual Super Bowl Week Hearing Mission, was held at the SportZone in Indianapolis.

4 Feb 2012

Scientists discover extremely long-lived proteins in aging rats

One of the big mysteries in biology is why cells age. Now scientists at the Salk Institute for Biological Studies report that they have discovered a weakness in a component of brain cells that may explain how the aging process occurs in the brain.

4 Feb 2012

Aspirin plus clopidogrel unlikely to prevent recurrent strokes and may increase risk of death, bleeding

The anti-blood clot regimen that adds the drug clopidogrel (Plavix) to aspirin treatment is unlikely to prevent recurrent strokes and may increase the risk of bleeding and death in patients with subcortical stroke according to late-breaking research presented at the American Stroke Association's International Stroke Conference 2012.

4 Feb 2012

Combination of Toca 511 and 5-FC may prolong survival in glioblastoma

Tocagen Inc. today announced the publication of data showing the company's investigational treatment for high grade glioma eradicates brain tumors and provides a dramatic survival benefit in mouse models of glioblastoma.

4 Feb 2012

Mineral and multivitamin supplements can lower risk of colon cancer

Could the use of vitamin and mineral supplements in a regular diet help to reduce the risk of colon cancer and protect against carcinogens? A study published in the Canadian Journal of Physiology and Pharmacology (CJPP) found that rats given regular multivitamin and mineral supplements showed a significantly lower risk of developing colon cancer when they were exposed to carcinogens.

4 Feb 2012

Whole exome sequencing provides clues about rare mutations in aneurysms

An innovative approach to genome screening has provided clues about rare mutations that may make people susceptible to brain aneurysms, predisposing them to brain bleeds, according to preliminary late-breaking research presented at the American Stroke Association's International Stroke Conference 2012.

4 Feb 2012