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TP63 gene correlates significantly with worse prognosis of melanoma

Scientists at Queen Mary, University of London have identified a gene present in some melanoma which appears to make the tumour cells more resistant to treatment, according to research published today in the Journal of Experimental Medicine.

19 Feb 2013

Outcomes no better with epidural steroids for patients with spinal stenosis

For patients with spinal stenosis, epidural steroid injections (ESI) may actually lead to worse outcomes-whether or not the patient later undergoes surgery, according to a study in the February 15 issue of Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

19 Feb 2013

Loyola proposes new subspecialty to diagnose and treat patients with depression, heart disease

A Loyola University Medical Center psychiatrist is proposing a new subspecialty to diagnose and treat patients who suffer both depression and heart disease. He's calling it "Psychocardiology."

19 Feb 2013

Sucampo's RESCULA 0.15% now available by prescription across the U.S.

Sucampo Pharmaceuticals, Inc. today announced that RESCULA (unoprostone isopropyl ophthalmic solution) 0.15% is now available by prescription across the United States. The U.S. Food and Drug Administration (FDA) approved a sNDA for RESCULA for the lowering of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension on December 7, 2012.

19 Feb 2013

Tranylcypromine may also hold promise in treating sickle cell disease

An antidepressant drug used since the 1960s may also hold promise for treating sickle cell disease, according to a surprising new finding made in mice and human red blood cells by a team from the University of Michigan Medical School.

19 Feb 2013

New system can help spot sleep disturbance in people with early dementia

A new sleep pattern monitoring system has been developed by UK researchers to help spot sleep disturbance in people diagnosed with early dementia. The system, known as PAViS, could be used remotely by healthcare workers to view sleep profiles and analyse sleep patterns based on sensory data gathered at the patient's home.

19 Feb 2013

Miniature, ultra-flexible electrodes could open new possibilities for more accurate and local DBS

Some 90,000 patients per year are treated for Parkinson's disease, a number that is expected to rise by 25 percent annually. Deep Brain Stimulation (DBS), which consists of electrically stimulating the central or peripheral nervous system, is currently standard practice for treating Parkinson's, but it can involve long, expensive surgeries with dramatic side effects. Miniature, ultra-flexible electrodes developed in Switzerland, however, could be the answer to more successful treatment for this and a host of other health issues.

19 Feb 2013

Reduced lung function during infancy may increase risk of wheezing in young adulthood

A study in Australia suggests that reduced lung function in infancy was associated with wheezing beyond childhood at 18 years of age, according to a report published Online First by JAMA Pediatrics, a JAMA Network publication.

19 Feb 2013

Study investigates whether music therapy reduces stress in cancer patients

A Saint Louis University Cancer Center pilot study is investigating whether music affects the health of cancer patients by soothing them and making them less anxious.

19 Feb 2013

Data from Eleven Biotherapeutics' EBI-005 preclinical study on ocular diseases

Eleven Biotherapeutics, a biopharmaceutical company creating novel and differentiated protein-based biotherapeutics, has published preclinical data in Proceedings of the National Academy of Sciences (PNAS) showing beneficial effects of EBI-005, the first rationally-designed topically administered IL-1 protein for the treatment of ocular diseases.

19 Feb 2013

New regeneration approach could be used for people with bladder issues

A new approach to bladder regeneration is capitalizing on the potential of two distinct cell populations harvested from a patient's healthy bone marrow, a new study reports.

19 Feb 2013

Study examines links between sitting time and chronic diseases in middle-aged Australian males

The more you sit, the higher your risk of chronic diseases. Kansas State University researcher Richard Rosenkranz, assistant professor of human nutrition, examined the associations of sitting time and chronic diseases in middle-aged Australian males in a study that is published in the International Journal of Behavioral Nutrition and Physical Activity. Collaborators include University of Western Sydney researchers Emma George and Gregory Kolt.

19 Feb 2013

Cholesterol metabolism regulated by bacteria in the small intestine

Researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, show that cholesterol metabolism is regulated by bacteria in the small intestine. These findings may be important for the development of new drugs for cardiovascular disease.

19 Feb 2013

Chiasma, Roche enter agreement to develop and commercialize Octreolin

Roche and Chiasma Inc., a privately held biopharma company, announced today that they have entered into an agreement to develop and commercialize Chiasma's proprietary product Octreolin, initially for acromegaly and subsequently for neuroendocrine tumors.

19 Feb 2013

Researchers design molecules that can stop colon cancer progression

A Basque research consortium has managed to halt the progress of colon cancer and its metastasis in the liver in an experimental model with mice. This advance, that may open a new path for the future treatment of such pathologies, has been achieved by creating molecules which interfere with the adhesion of tumour cells to other cells of the organism. In this way, the molecules halt both the growth of the tumour and the dissemination of the tumour to and its proliferation in other organs.

19 Feb 2013

Fibromyalgia prevalence is 2.1% of the general population in Germany

Researchers have determined that fibromyalgia prevalence is 2.1% of the general population in Germany. Results appearing in Arthritis Care & Research, a journal published by Wiley on behalf of the American College of Rheumatology (ACR), suggest that fibromyalgia is a spectrum disorder rather than a categorical illness. Additionally, a number of fibromyalgia cases in the general population satisfy proposed criteria for physical symptom disorder—the presence of one or more physical symptoms that impair function, which cannot be explained by another clinical or psychiatric illness.

19 Feb 2013

Study describes pharmacological action of TZDs directly on pancreas

A scientific study published on the journal Diabetes, edited by the American Diabetes Association, describes for the first time the pharmacological action of thiazolidinediones (TZDs) —anti-diabetic drugs— directly on pancreas, the organ which produces insulin.

18 Feb 2013

Article details mechanism by which long non-coding RNA-activators promote gene expression

Long segments of RNA- encoded in our DNA but not translated into protein-are key to physically manipulating DNA in order to activate certain genes, say researchers at The Wistar Institute. These non-coding RNA-activators (ncRNA-a) have a crucial role in turning genes on and off during early embryonic development, researchers say, and have also been connected with diseases, including some cancers, in adults.

18 Feb 2013

Roles of diet, energy expenditures in rising obesity rates to be presented at AAAS meeting

William Leonard has conducted extensive research on the diets and ways of prehistoric populations. A paper on his research will be presented Friday, Feb. 15, at the annual meeting of the American Association for the Advancement of Science (AAAS).

18 Feb 2013

Royal Holloway University launches new iPad app to help people with macular disease

Scientists from Royal Holloway University are launching a new iPad app to help people with macular disease, the most common cause of sight loss in the UK.

18 Feb 2013

Medical Condition News

TP63 gene correlates significantly with worse prognosis of melanoma

Outcomes no better with epidural steroids for patients with spinal stenosis

Loyola proposes new subspecialty to diagnose and treat patients with depression, heart disease

Sucampo's RESCULA 0.15% now available by prescription across the U.S.

Tranylcypromine may also hold promise in treating sickle cell disease

New system can help spot sleep disturbance in people with early dementia

Miniature, ultra-flexible electrodes could open new possibilities for more accurate and local DBS

Reduced lung function during infancy may increase risk of wheezing in young adulthood

Study investigates whether music therapy reduces stress in cancer patients

Data from Eleven Biotherapeutics' EBI-005 preclinical study on ocular diseases

New regeneration approach could be used for people with bladder issues

Study examines links between sitting time and chronic diseases in middle-aged Australian males

Cholesterol metabolism regulated by bacteria in the small intestine

Chiasma, Roche enter agreement to develop and commercialize Octreolin

Researchers design molecules that can stop colon cancer progression

Fibromyalgia prevalence is 2.1% of the general population in Germany

Study describes pharmacological action of TZDs directly on pancreas

Article details mechanism by which long non-coding RNA-activators promote gene expression

Roles of diet, energy expenditures in rising obesity rates to be presented at AAAS meeting

Royal Holloway University launches new iPad app to help people with macular disease

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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