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FDA grants orphan drug status to Lentigen’s LG631-CD34 for treatment of glioblastoma multiforme

Lentigen Corporation, a biotechnology company specializing in the development and manufacture of lentiviral gene delivery products, announced today that that the U.S. Food and Drug Administration (FDA) has granted orphan drug status to P140K methylguanine methyltransferase (MGMT) transduced human CD34 cells for bone marrow protection in the treatment of glioblastoma multiforme.

14 Feb 2013

Mindfulness practitioners gain enhanced control over sensory cortical alpha rhythms

Why does training in mindfulness meditation help patients manage chronic pain and depression? In a newly published neurophysiological review, Brown University scientists propose that mindfulness practitioners gain enhanced control over sensory cortical alpha rhythms that help regulate how the brain processes and filters sensations, including pain, and memories such as depressive cognitions.

14 Feb 2013

New paper advances scientific understanding of glycoproteins’ structure and function

A Simon Fraser University chemist is the lead author on a new paper that advances scientific understanding of the structure and function of glycoproteins, in particular the number and positioning of sugars on them.

14 Feb 2013

Triple-negative breast cancers more biologically diverse than previously believed

Triple-negative breast cancers are more biologically diverse than previously believed and classification should be expanded to reflect this heterogeneity, according to University of North Carolina researchers.

14 Feb 2013

DBS can lead to long-term improvement in patients with neuropathic pain

For many patients with difficult-to-treat neuropathic pain, deep brain stimulation (DBS) can lead to long-term improvement in pain scores and other outcomes, according to a study in the February issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

14 Feb 2013

FDA grants final approval to Breckenridge’s Pioglitazone Hydrochloride ANDA

Breckenridge Pharmaceutical, Inc. announced today the immediate launch of Pioglitazone Hydrochloride Tablets. The U.S. Food and Drug Administration granted final approval for the Abbreviated New Drug Application (ANDA), which is being manufactured and supplied by Synthon Pharmaceuticals, Inc., and will be available in 15 mg, 30 mg, and 45 mg strengths.

14 Feb 2013

TP PCR methodology may help streamline genetic testing for Huntington's

A new test may help to streamline genetic testing for Huntington Disease (HD) by generating accurate results, avoiding unnecessary additional testing, and improving turnaround time.

14 Feb 2013

FDA allows Scioderm’s SD-101 IND application for Epidermolysis Bullosa to proceed

Scioderm announced that the US Food and Drug Administration (FDA) has reviewed and allowed the investigational new drug (IND) application for SD-101 to proceed. SD-101 is a topical treatment being developed for the treatment of Epidermolysis Bullosa (EB).

14 Feb 2013

CATT study clarifies value of genetic testing for age-related macular degeneration

New findings from a landmark clinical trial show that although certain gene variants may predict whether a person is likely to develop age-related macular degeneration (AMD), a potentially blinding eye disease that afflicts more than nine million Americans, these genes do not predict how patients will respond to Lucentis- and Avastin-, the two medications most widely used to treat the "wet" form of AMD.

13 Feb 2013

Examining politics of reaching NCD targets

Writing in the PLoS blog "Translational Global Health," Greg Paton, a public health consultant, discusses the history of and current discussions taking place surrounding global targets for non-communicable diseases (NCDs).

13 Feb 2013

Meridian receives ADA's Certificate of Education Recognition for diabetes education program

The American Diabetes Association (ADA) has awarded Meridian Medical Associates a Certificate of Education Recognition for its diabetes self-management education program.

13 Feb 2013

Researchers investigate new avenue of treatment to help boost poor pancreatic cancer survival rates

Researchers at Georgia Regents University Cancer Center are investigating a new avenue of treatment to help boost poor pancreatic cancer survival rates.

13 Feb 2013

Ability to tune gene activity will permit refined research for drug resistance, cancer

Scientists who built a synthetic gene circuit that allowed for the precise tuning of a gene's expression in yeast have now refined this new research tool to work in human cells, according to research published online in Nature Communications.

13 Feb 2013

Scientists identify aromatic rice with very low arsenic content

Millions of people worldwide are regularly exposed to arsenic through drinking water and eating rice grown in soil and water containing high amounts of arsenic. Long-term exposure can lead to the development of different types of cancer as well as serious cardiovascular, neurological, and other health problems. Scientists have now identified aromatic rice from Bangladesh that has far lower arsenic concentrations than found in non-aromatic rice.

13 Feb 2013

Tivozanib overall survival results announced by AVEO and Astellas

AVEO Oncology (NASDAQ: AVEO) and Astellas Pharma Inc. (TSE: 4503) announced overall survival (OS) for tivozanib, an investigational agent, from the Phase 3 TIVO-1 (TIvozanib Versus sOrafenib in 1st line advanced RCC) study in patients with advanced renal cell carcinoma (RCC). The final OS analysis, as specified by the protocol, shows a median OS of 28.8 months (95% confidence interval [CI]: 22.5–NA) for tivozanib versus a median OS of 29.3 months (95% CI: 29.3–NA) for the comparator arm, sorafenib.

13 Feb 2013

Military deployment increases risk of maternal depression in female service members

About 16,000 women on active duty in the U.S. military give birth each year. Most return to service after 6 weeks and can be deployed after 4 months. The potential for an increased risk of depression among new mothers who deploy and are exposed to combat experience is presented in a study published in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

13 Feb 2013

Less than 1 in 4 young people with ASD receive transition services

Health care transition (HCT) services help young people with special health care needs such as asthma or diabetes move from pediatric to adult health care. However, youths with autism spectrum disorder (ASD) have less access to these services, which are designed to prevent gaps in care and insurance coverage.

13 Feb 2013

Platelet-rich plasma holds great promise in treating knee OA

A study by researchers from Hospital for Special Surgery has shown that platelet-rich plasma (PRP) holds great promise for treating patients with knee osteoarthritis.

13 Feb 2013

Scopolamine may also be possible treatment for anxiety disorders

However, scopolamine is re-emerging as an antidepressant, with recent studies showing that scopolamine can rapidly improve mood in depressed patients. In addition, in a new study published in Biological Psychiatry this month by Dr. Moriel Zelikowsky and colleagues at the University of California, Los Angeles, it may also be a possible treatment for anxiety disorders.

13 Feb 2013

HRI to begin enrollment in RAD001 Phase II trial for Neurofibromatosis Type-2

House Research Institute (HRI) is recruiting patients for a Phase II clinical trial to test a medication that may slow the progression of Neurofibromatosis Type-2, commonly referred to as NF2.

13 Feb 2013

Medical Condition News

FDA grants orphan drug status to Lentigen’s LG631-CD34 for treatment of glioblastoma multiforme

Mindfulness practitioners gain enhanced control over sensory cortical alpha rhythms

New paper advances scientific understanding of glycoproteins’ structure and function

Triple-negative breast cancers more biologically diverse than previously believed

DBS can lead to long-term improvement in patients with neuropathic pain

FDA grants final approval to Breckenridge’s Pioglitazone Hydrochloride ANDA

TP PCR methodology may help streamline genetic testing for Huntington's

FDA allows Scioderm’s SD-101 IND application for Epidermolysis Bullosa to proceed

CATT study clarifies value of genetic testing for age-related macular degeneration

Examining politics of reaching NCD targets

Meridian receives ADA's Certificate of Education Recognition for diabetes education program

Researchers investigate new avenue of treatment to help boost poor pancreatic cancer survival rates

Ability to tune gene activity will permit refined research for drug resistance, cancer

Scientists identify aromatic rice with very low arsenic content

Tivozanib overall survival results announced by AVEO and Astellas

Military deployment increases risk of maternal depression in female service members

Less than 1 in 4 young people with ASD receive transition services

Platelet-rich plasma holds great promise in treating knee OA

Scopolamine may also be possible treatment for anxiety disorders

HRI to begin enrollment in RAD001 Phase II trial for Neurofibromatosis Type-2

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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