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NewLink Genetics to launch algenpantucel-L Phase 3 study in pancreatic cancer

NewLink Genetics Corporation announces launching of an open-label, randomized, multi-institutional Phase 3 study in patients with borderline resectable or locally advanced unresectable pancreatic cancer.

10 Oct 2012

People with diabetic foot ulcers more likely to die prematurely

People with diabetes who develop foot ulcers are at more risk of dying prematurely than those without the complication, finds a new large-scale study. The researchers say the findings highlight the potential need for improved detection and management of those with diabetes and foot ulcers.

10 Oct 2012

HbA1c converter tool launched by NPS

NPS MedicineWise has launched a new online HbA1c converter tool to help people with diabetes understand changes to the way their HbA1c test results are reported in Australia.

10 Oct 2012

Spanish and British scientists design new blood test to identify aggressive prostate cancer

Scientists from the Spanish National Cancer Research Centre (CNIO) in Madrid, along with British colleagues from the Institute for Cancer Research (ICR) and the Royal Marsden NHS Foundation Trust, have developed a test that studies genetic patterns in blood cells to detect advanced-stage prostate cancer.

10 Oct 2012

Scientists discover mechanism used by A20 protein to combat inflammation

Scientists affiliated with VIB and UGent have discovered a mechanism used by the protein A20 to combat inflammation. This could be a very important point of focus in the search for a treatment for autoimmune diseases such as Rheumatoid Arthritis, in which the patient suffers from chronic, uncontrolled inflammation.

10 Oct 2012

Physical activity associated with increased risk of bleeding in children with hemophilia

Hemophilia is a bleeding disorder that, if untreated, causes recurrent bleeding into joints. "Vigorous physical activity is thought to increase risk of bleeds in children with hemophilia, but the magnitude of the risk is unknown," according to background information in the article. Information about risks associated with physical activity is needed to help inform decisions regarding participation in physical activity, the authors write.

10 Oct 2012

Dieting, exercise can spur HDL cholesterol production in type 2 diabetics

With a little exercise and dieting, overweight people with type 2 diabetes can still train their fat cells to produce a hormone believed to spur HDL cholesterol production, report medical researchers from The Methodist Hospital and eight other institutions in an upcoming issue of the Journal of Lipid Research.

10 Oct 2012

Romney's pre-existing conditions plan questioned

News outlets examine this aspect of GOP presidential candidate Mitt Romney's health care policies and report that it would only help a fraction of the country's uninsured.

10 Oct 2012

Nearly all groups of patients with spinal stenosis do better with surgery

Nearly all groups of patients with spinal stenosis—but not smokers—do better with surgery than with nonsurgical treatment, reports a study in the October 1 issue of Spine.

10 Oct 2012

Proneurotensin associated with diabetes, cardiometabolic disease and breast cancer

Plasma levels of proneurotensin are associated with the development of diabetes, cardiovascular disease, cardiovascular and total mortality, and breast cancer in women during long-term follow-up, according to a study in the October 10 issue of JAMA.

10 Oct 2012

Decrease in doctor appointments, preventable hospital visits draw scrutiny

Medpage Today offers a pair of stories exploring Census findings regarding doctor visits in 2010 as well as MedPAC's interest in "preventable" hospital visits.

10 Oct 2012

High-fat Western diet could lead to development of atherosclerosis

Columbia University Medical Center (CUMC) researchers have found that a diet high in saturated fat raises levels of endothelial lipase (EL), an enzyme associated with the development of atherosclerosis, and, conversely, that a diet high in omega-3 polyunsaturated fat lowers levels of this enzyme.

10 Oct 2012

ASTRO names distinguished neurosurgeon as 2012 Honorary Member

The American Society for Radiation Oncology (ASTRO) has named Mark P. Carol, MD, a distinguished leader in the fields of intensity modulated radiation therapy (IMRT) and image-guided radiation therapy (IGRT), as its 2012 Honorary Member, which is the highest honor the Society bestows upon distinguished cancer researchers and leaders in disciplines other than radiation oncology, radiation physics or radiobiology.

10 Oct 2012

Chemotherapy plus immunotherapy can enhance anti-tumor effects in patients with advanced cancer

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and Tianjin Medical University Cancer Institute and Hospital in China have discovered that combining chemotherapy drugs and immunotherapy cancer vaccines results in an enhanced anti-tumor effect.

10 Oct 2012

NACA could prevent or cure cataracts, macular degeneration and other eye conditions

Researchers at Missouri University of Science and Technology are working with an antioxidant that could prevent or cure cataracts, macular degeneration and other degenerative eye disorders.

10 Oct 2012

Boston Scientific initiates enrollment in Lotus Valve System clinical trial for aortic valve disease

Boston Scientific has enrolled the first patient in the REPRISE II clinical trial to evaluate the safety and performance of the Lotus Valve System in up to 120 patients with severe aortic valve disease.

10 Oct 2012

EHRs enhance quality of patient care in community-based settings

A new study by Weill Cornell Medical College researchers, published in the Journal of General Internal Medicine, provides compelling evidence that electronic health records (EHRs) enhance the quality of patient care in a community-based setting with multiple payers, which is representative of how medicine is generally practiced across the United States.

10 Oct 2012

Mylan, Shionogi and CIMA Labs to resolve generic Orapred ODT patent litigation

Mylan Inc. today announced that it has entered into a settlement agreement with Shionogi Inc. and CIMA Labs Inc. that will resolve patent litigation related to Prednisolone Sodium Phosphate Orally Disintegrating Tablets (ODT), 10 mg, 15 mg and 30 mg.

10 Oct 2012

Modifying factors may be responsible for non-diabetic kidney disease in African-Americans

The high rate of non-diabetic kidney disease in African-Americans is strongly associated with variations in a particular gene. Yet, not everyone who inherits these variations develops the disease.

10 Oct 2012

Recovering Treg cells in pancreatic lymph nodes may restore insulin production in type I diabetics

The key to restoring production of insulin in type I diabetic patients, previously known as juvenile diabetes, may be in recovering the population of protective cells known T regulatory cells in the lymph nodes at the "gates" of the pancreas, a new preclinical study published online October 8 in Cellular & Molecular Immunology by researchers in the Department of Bioscience Technologies at Thomas Jefferson University suggests.

10 Oct 2012

Medical Condition News

NewLink Genetics to launch algenpantucel-L Phase 3 study in pancreatic cancer

People with diabetic foot ulcers more likely to die prematurely

HbA1c converter tool launched by NPS

Spanish and British scientists design new blood test to identify aggressive prostate cancer

Scientists discover mechanism used by A20 protein to combat inflammation

Physical activity associated with increased risk of bleeding in children with hemophilia

Dieting, exercise can spur HDL cholesterol production in type 2 diabetics

Romney's pre-existing conditions plan questioned

Nearly all groups of patients with spinal stenosis do better with surgery

Proneurotensin associated with diabetes, cardiometabolic disease and breast cancer

Decrease in doctor appointments, preventable hospital visits draw scrutiny

High-fat Western diet could lead to development of atherosclerosis

ASTRO names distinguished neurosurgeon as 2012 Honorary Member

Chemotherapy plus immunotherapy can enhance anti-tumor effects in patients with advanced cancer

NACA could prevent or cure cataracts, macular degeneration and other eye conditions

Boston Scientific initiates enrollment in Lotus Valve System clinical trial for aortic valve disease

EHRs enhance quality of patient care in community-based settings

Mylan, Shionogi and CIMA Labs to resolve generic Orapred ODT patent litigation

Modifying factors may be responsible for non-diabetic kidney disease in African-Americans

Recovering Treg cells in pancreatic lymph nodes may restore insulin production in type I diabetics

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

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