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Scientists discover natural trigger that enables stem cell development

A natural trigger that enables stem cells to become any cell-type in the body has been discovered by scientists.

10 Feb 2013

SUVmax may help indicate progression-free survival in stage I NSCLC patients treated with SBRT

SUVmax (Maximum Standardized Uptake Value) may be a significant and clinically independent marker to indicate progression-free survival in stage I non-small cell lung cancer (NSCLC) patients treated with stereotactic body radiation therapy (SBRT), according to research being presented at the 2013 Cancer Imaging and Radiation Therapy Symposium.

10 Feb 2013

Overexpression of alpha-synuclein can cause Parkinson's

Researchers at the University of California, San Diego School of Medicine say overexpression of a protein called alpha-synuclein appears to disrupt vital recycling processes in neurons, starting with the terminal extensions of neurons and working its way back to the cells' center, with the potential consequence of progressive degeneration and eventual cell death.

10 Feb 2013

Infusions of regulatory T cells turn off autoimmune attack on joints

Farber Cancer Institute scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis in a mouse model. They say it holds promise for improved treatment of arthritis and other autoimmune disorders in people.

10 Feb 2013

Harvard's Wyss Institute completes first clinical study of new rapid neuroassessment device

Doctors routinely track their patients' hand-eye coordination to monitor any neuromuscular deficits, particularly as patients age or when they are injured -- but the tests they have been using to track this kind of information may be subjective and qualitative.

10 Feb 2013

Sunitinib shows promise against metastatic renal cell carcinoma

Findings from clinical trial patients with metastatic renal cell carcinoma, a common kidney cancer, show they did not have accelerated tumor growth after treatment with sunitinib, in contrast to some study results in animals. Sunitinib is one of several drugs, either on the market or undergoing testing, that target blood vessel growth.

10 Feb 2013

Frequent hemodialysis can cause vascular complications in patients

Compared with standard dialysis, frequent dialysis can cause complications related to repeated access to the blood, requiring patients to undergo more repair procedures to the site through which blood is removed and returned, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

10 Feb 2013

Northwestern Medicine expert offers tips to battle seasonal affective disorder

Winter is in full force. With short days and less exposure to sunlight, everyone feels less energetic and more people are vulnerable to depression. Seasonal Affective Disorder (SAD), or winter depression, is a mood disorder related to seasonal variations of light. Symptoms start in late fall and oftentimes last until April or early spring. It affects between 10 to 20 percent of Americans, primarily younger adults and women.

10 Feb 2013

Biogen Idec, Sobi release data from rFVIIIFc and rFIXFc phase 3 trials on hemophilia

Biogen Idec and Swedish Orphan Biovitrum (Sobi) released data that confirmed the ability of investigational recombinant factors VIII Fc fusion protein (rFVIIIFc) and IX Fc fusion protein (rFIXFc) to provide long-lasting protection from bleeding with fewer injections than are required with the current standard of care for people with hemophilia.

10 Feb 2013

New insights on role of placebo in depression

A randomized controlled trial published in one of the last issue of Psychotherapy and Psychosomatics unravels new insights on the role of placebo in depression.

10 Feb 2013

Scientists discover recurring pattern of more than 13,000 epigenetic alterations in young tumours

Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction between the genetic and epigenetic mechanisms is critical for the selection of tumour biomarkers and for the future development of therapies. Human tumour specimens and cell lines however contain a plethora of genetic and epigenetic changes, which complicate data analysis.

10 Feb 2013

Combination of two antibodies prevents growth and spread of triple-negative breast tumors

Cancer drugs of the new, molecular generation destroy malignant breast tumors in a targeted manner: They block characteristic molecules on tumor cells - receptors for the hormones estrogen or progesterone, or a co-receptor, called HER2, that binds to many growth factors. But about one in every six breast tumors has none of these receptors. Such cancers, called triple-negative, are particularly aggressive and notoriously difficult to treat.

10 Feb 2013

Virginia Tech researchers reveal how 'bad' gut bacteria may help control diabetes

A stomach bacterium believed to cause health problems such as gastritis, ulcers, and gastric cancer may play a dual role by balancing the stomach's ecosystem and controlling body weight and glucose tolerance, according to immunologists at the Virginia Bioinformatics Institute of Virginia Tech.

10 Feb 2013

Inhibiting JNK enzyme protects against ischemic/reperfusion injury

Using two different compounds they developed, scientists from the Florida campus of The Scripps Research Institute (TSRI) have been able to show in animal models that inhibiting a specific enzyme protects heart cells and surrounding tissue against serious damage from heart attacks.

10 Feb 2013

Tat-beclin 1 shows promise against infections, neurodegenerative disorders and cancer

UT Southwestern Medical Center scientists have synthesized a peptide that shows potential for pharmaceutical development into agents for treating infections, neurodegenerative disorders, and cancer through an ability to induce a cell-recycling process called autophagy.

10 Feb 2013

UIC receives $2.3M federal grant to study how young adults use new tobacco products

Researchers at the University of Illinois at Chicago's Institute for Health Research and Policy have received a $2.3 million federal grant to study how young adults use hookahs, snus, electronic cigarettes, and other new tobacco products.

10 Feb 2013

Research sheds light on how E. coli thrive in the intestine of people with IBD

Scientists have long puzzled over why "bad" bacteria such as E. coli can thrive in the guts of those with inflammatory bowel disease (IBD), causing serious diarrhea. Now UC Davis researchers have discovered the answer-one that may be the first step toward finding new and better treatments for IBD.

10 Feb 2013

Report: The number of Americans with Alzheimer's disease will almost triple by 2050

The government-funded report projects the Alzheimer's cases will rise from 5 million to about 13.8 million, thereby straining the nation's health care system.

10 Feb 2013

Single gene therapy session can cure diabetes

Researchers from the Universitat Aut-noma de Barcelona (UAB), led by F-tima Bosch, have shown for the first time that it is possible to cure diabetes in large animals with a single session of gene therapy. As published this week in Diabetes, the principal journal for research on the disease, after a single gene therapy session, the dogs recover their health and no longer show symptoms of the disease.

10 Feb 2013

Reprogrammed human skin cells highly effective in treating myelin disorders

A study out today in the journal Cell Stem Cell shows that human brain cells created by reprogramming skin cells are highly effective in treating myelin disorders, a family of diseases that includes multiple sclerosis and rare childhood disorders called pediatric leukodystrophies.

10 Feb 2013

Medical Condition News

Scientists discover natural trigger that enables stem cell development

SUVmax may help indicate progression-free survival in stage I NSCLC patients treated with SBRT

Overexpression of alpha-synuclein can cause Parkinson's

Infusions of regulatory T cells turn off autoimmune attack on joints

Harvard's Wyss Institute completes first clinical study of new rapid neuroassessment device

Sunitinib shows promise against metastatic renal cell carcinoma

Frequent hemodialysis can cause vascular complications in patients

Northwestern Medicine expert offers tips to battle seasonal affective disorder

Biogen Idec, Sobi release data from rFVIIIFc and rFIXFc phase 3 trials on hemophilia

New insights on role of placebo in depression

Scientists discover recurring pattern of more than 13,000 epigenetic alterations in young tumours

Combination of two antibodies prevents growth and spread of triple-negative breast tumors

Virginia Tech researchers reveal how 'bad' gut bacteria may help control diabetes

Inhibiting JNK enzyme protects against ischemic/reperfusion injury

Tat-beclin 1 shows promise against infections, neurodegenerative disorders and cancer

UIC receives $2.3M federal grant to study how young adults use new tobacco products

Research sheds light on how E. coli thrive in the intestine of people with IBD

Report: The number of Americans with Alzheimer's disease will almost triple by 2050

Single gene therapy session can cure diabetes

Reprogrammed human skin cells highly effective in treating myelin disorders

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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