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NIH awards $2.1M grant to study possible ways to fight cancer

A professor with the University of Houston Cullen College of Engineering has won a $2.1 million grant to study the best ways to modify human immune cells to fight against cancer.

6 Oct 2012

Rember revamped for Phase 3 testing in behavioral-variant frontotemporal dementia

Rember—the blue dye that created a stir in 2008 when Phase 2 clinical trial data claimed that it slowed decline in people with Alzheimer's disease—has now been revamped for Phase 3 testing in another disease, behavioral-variant frontotemporal dementia (bvFTD).

6 Oct 2012

Researchers from three trials join to collaborate under European Dementia Prevention Initiative

Worldwide, the number of people with Alzheimer's disease will hit 115 million by 2050, according to the World Health Organization. Scientists, health officials, policymakers, and the public are asking if anything can slow down the disease.

6 Oct 2012

BUSM leads genome-wide evaluation of genetic variants associated with Parkinson's disease

Boston University School of Medicine investigators have led the first genome-wide evaluation of genetic variants associated with Parkinson's disease (PD). The study, which is published online in PLOS ONE, points to the involvement of specific genes and alterations in their expression as influencing the risk for developing PD.

6 Oct 2012

Benzodiazepine exposure for over-65s linked to increased risk of dementia

The results from comparative analysis of this population demonstrate the risk of developing dementia increased by 50% for subjects who consumed benzodiazepines during the follow-up period, compared with those who had never used benzodiazepines.

6 Oct 2012

Researchers discover brain mechanism responsible for sensation of nausea

Nausea is a common and distressing side effect of many drugs and treatments. Unlike vomiting, nausea is not well understood, but new research by University of Guelph scientists may soon change that.

6 Oct 2012

Two genes linked to increased risk of diabetes-associated kidney disease

An international group of researchers has discovered two genes that increase the risk of developing diabetes-associated kidney disease.

6 Oct 2012

Public health significance and societal consequences of pathological gambling

The panel discussion on the occasion of the 25th ECNP Congress in Vienna, Austria, will focus not only on medical issues of pathological gambling, but also on its public health significance and societal consequences.

6 Oct 2012

RXi receives SBIR grant to enable discovery and preclinical development of sd-rxRNAs

RXi Pharmaceuticals Corporation, a biotechnology company focused on discovering, developing and commercializing innovative therapies addressing major unmet medical needs using RNA-targeted technologies, today announced that it was awarded a Small Business Innovation Research (SBIR) grant by the National Cancer Institute (NCI) of the National Institutes of Health (NIH).

5 Oct 2012

MannKind completes enrollment in AFREZZA Phase 3 clinical studies for type 1 and 2 diabetes

MannKind Corporation today announced that it has completed recruiting patients for two Phase 3 clinical studies of AFREZZA (insulin human [rDNA origin]), an investigational, ultra rapid-acting mealtime insulin therapy, administered using MannKind's to-be-marketed next-generation inhaler.

5 Oct 2012

Home hemodialysis more accessible than ever

Most patients with chronic kidney disease who undergo hemodialysis put up with a grueling treatment regimen that involves going into a clinic several days a week and sitting through a three-to-four hour dialysis session at each visit. Home hemodialysis is more accessible than ever, though, with the advent of newer systems that are easier for patients to learn, use, and maintain, according to a review appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

5 Oct 2012

UCLA project to promote healthy nutrition and physical activity to curb obesity

Researchers at the UCLA Fielding School of Public Health and UCLA's Jonsson Comprehensive Cancer Center have been awarded a $20 million federal grant to further their innovative efforts to curb obesity, a global pandemic that has reached the level of a national crisis in the United States.

5 Oct 2012

Paper proposes novel mathematical models for injection of insulin in type 1 and 2 diabetes

Diabetes mellitus is a chronic disease in which individuals exhibit high levels of sugar in the blood, either due to insufficient production of insulin-the hormone that allows glucose to be absorbed by body cells-or the body's lack of response to insulin. Type 1 diabetes occurs due to loss or dysfunction of β-cells of the pancreas, the organ that produces insulin. Type 2 diabetes is caused by a defective glucose-insulin regulatory system.

5 Oct 2012