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Celgene's Pomalyst receives FDA approval for treatment of multiple myeloma

The U.S. Food and Drug Administration today approved Pomalyst (pomalidomide) to treat patients with multiple myeloma whose disease progressed after being treated with other cancer drugs.

10 Feb 2013

Celgene receives FDA approval for POMALYST to treat multiple myeloma

Celgene Corporation today announced the U.S. Food and Drug Administration (FDA) has approved POMALYST brand therapy (pomalidomide) for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and bortezomib and have demonstrated disease progression on or within 60 days of completion of the last therapy.

10 Feb 2013

Broken motors induce stress and anxiety in mice

When motors break down, getting where you want to go becomes a struggle. Problems arise in much the same way for critical brain receptors when the molecular motors they depend on fail to operate. Now, researchers reporting in Cell Reports, a Cell Press publication, on February 7, have shown these broken motors induce stress and anxiety in mice. The discovery may point the way to new kinds of drugs to treat anxiety and other disorders.

10 Feb 2013

Positive data from POZEN's PA32540 Phase 3 studies presented at AHA 2013 stroke conference

POZEN Inc., a pharmaceutical company committed to transforming medicine that transforms lives, presented data today from the combined results of two Phase 3 studies of PA32540, an antiplatelet therapy of enteric-coated (EC) and immediate-release omeprazole, in patients with previous cerebrovascular disease.

10 Feb 2013

Bronchiectasis independently associated with increased mortality risk in COPD patients

Bronchiectasis is independently associated with an increased mortality risk in patients with moderate-to-severe COPD, according to a new study from researchers in Spain.

10 Feb 2013

International Association of Eating Disorders Professionals to kick off 27th annual symposium

The International Association of Eating Disorders Professionals (iaedp) kicks off its 27th annual Symposium March 21-24 at the Westin Lake Las Vegas Resort and Spa and will feature five nationally recognized professionals addressing new treatments and research concerning eating disorders.

10 Feb 2013

MMRF joins multiple myeloma community in celebrating FDA accelerated approval of Pomalyst

The Multiple Myeloma Research Foundation (MMRF) today joined the multiple myeloma community in celebrating the U.S. Food and Drug Administration's (FDA) decision to grant accelerated approval of Pomalyst (Celgene Corporation, pomalidomide) for the treatment of patients with relapsed and refractory multiple myeloma who no longer respond to currently available treatments.

10 Feb 2013

Researchers develop special version of iDichotic for patients with schizophrenia

Two years ago, researcher Josef Bless was listening to music on his phone when he suddenly had an idea. "I noticed that the sounds of the different instruments were distributed differently between the ears, and it struck me that this was very similar to the tests we routinely use in our laboratory to measure brain function. In dichotic listening, each ear is presented with a different syllable at the same time and the listener has to say which syllable seems clearest. The test indicates which side of the brain is most active during language processing," Bless explains.

10 Feb 2013

TGFβ inhibition enhances chemotherapy action against triple negative breast cancer

Due to chemotherapy resistance and a high rate of relapse, triple negative cancers are among the most difficult breast cancers to treat. In this issue of the Journal of Clinical Investigation, researchers led by Carlos Arteaga at Vanderbilt University identified a protein, TGF-β, that is highly expressed in triple negative breast cancer cells after chemotherapy.

10 Feb 2013

Weekend reading: Mental health discrimination; A doctor faces hard questions; Long-term outlook for health care jobs

"When I had cancer, I got cards and flowers," Karen Kangas' sign reads. "When I was diagnosed with bipolar disorder, I got no cards and a pink slip." A picture of Kangas holding the sign hangs in the state Capitol complex, part of an exhibit called "Discrimination: A Roadblock to Recovery."

9 Feb 2013

LPA genetic variant increases risk of heart valve calcification

Researchers have found a genetic variant that doubles the likelihood that people will have calcium deposits on their aortic valve. Such calcification, if it becomes severe, can cause narrowing or a blockage of the aortic valve, a condition called aortic stenosis.

9 Feb 2013

Study finds reason why patients with chronic pain often suffer from impaired short -term memory

A group of Portuguese researchers from IBMC and FMUP at the University of Porto has found the reason why patients with chronic pain often suffer from impaired short -term memory.

9 Feb 2013

Marijuana may double stroke risk in young adults

Marijuana, the most widely used illicit drug, may double stroke risk in young adults, according to research presented at the American Stroke Association's International Stroke Conference 2013.

9 Feb 2013

Positive data from Oncolytics' REOLYSIN Phase 2 combination trial on SCCLC

Oncolytics Biotech Inc. today announced results examining percent overall tumour shrinkage data from its U.S. Phase 2 clinical trial in patients with squamous cell carcinoma of the lung (SCCLC) using intravenous administration of REOLYSIN in combination with carboplatin and paclitaxel (REO 021).

9 Feb 2013

Drugs that target retromer pathway could help prevent or treat Parkinson's

Columbia University Medical Center (CUMC) researchers have identified a protein trafficking defect within brain cells that may underlie common non-familial forms of Parkinson's disease.

9 Feb 2013

Older adults with COPD more frequently use benzodiazepines

A popular class of drugs commonly used to treat sleep and mood symptoms continues to be frequently prescribed despite being known to have potentially life-threatening side effects.

9 Feb 2013

Academic medical centers play an integral role in developing new treatments and cures

As an internationally recognized researcher into aging and dementia, Suzanne Craft is keenly aware of the importance of volunteers in clinical studies.

9 Feb 2013

Alzheimer's appears to be on the rise

The number of people with Alzheimer's disease is expected to triple in the next 40 years, according to a new study by researchers from Rush University Medical Center published in the February 6, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

9 Feb 2013

Scientists create nanoscale vehicle to battle cancer without harming healthy cells

A tiny capsule invented at a UCLA lab could go a long way toward improving cancer treatment. Devising a method for more precise and less invasive treatment of cancer tumors, a team led by researchers from the UCLA Henry Samueli School of Engineering and Applied Science has developed a degradable nanoscale shell to carry proteins to cancer cells and stunt the growth of tumors without damaging healthy cells.

9 Feb 2013

TIC10 may improve usefulness of TRAIL protein in cancer therapy

A compound that stimulates the production of a tumor-fighting protein may improve the usefulness of the protein in cancer therapy, according to a team of researchers.

9 Feb 2013

Medical Condition News

Celgene's Pomalyst receives FDA approval for treatment of multiple myeloma

Celgene receives FDA approval for POMALYST to treat multiple myeloma

Broken motors induce stress and anxiety in mice

Positive data from POZEN's PA32540 Phase 3 studies presented at AHA 2013 stroke conference

Bronchiectasis independently associated with increased mortality risk in COPD patients

International Association of Eating Disorders Professionals to kick off 27th annual symposium

MMRF joins multiple myeloma community in celebrating FDA accelerated approval of Pomalyst

Researchers develop special version of iDichotic for patients with schizophrenia

TGFβ inhibition enhances chemotherapy action against triple negative breast cancer

Weekend reading: Mental health discrimination; A doctor faces hard questions; Long-term outlook for health care jobs

LPA genetic variant increases risk of heart valve calcification

Study finds reason why patients with chronic pain often suffer from impaired short -term memory

Marijuana may double stroke risk in young adults

Positive data from Oncolytics' REOLYSIN Phase 2 combination trial on SCCLC

Drugs that target retromer pathway could help prevent or treat Parkinson's

Older adults with COPD more frequently use benzodiazepines

Academic medical centers play an integral role in developing new treatments and cures

Alzheimer's appears to be on the rise

Scientists create nanoscale vehicle to battle cancer without harming healthy cells

TIC10 may improve usefulness of TRAIL protein in cancer therapy

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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