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SOD1 enzyme protects cells by regulating cell energy and metabolism

Just like a comic book super hero, you could say that the enzyme superoxide dismutase (SOD1) has a secret identity. Since its discovery in 1969, scientists believed SOD1's only role was to protect living cells against damage from free radicals. Now, researchers at the Johns Hopkins Bloomberg School of Public Health have discovered that SOD1 protects cells by regulating cell energy and metabolism. The results of their research were published January 17, 2013, in the journal Cell.

30 Jan 2013

Acceleron commences ACE-536 phase 2 study in myelodysplastic syndromes

Acceleron Pharma, Inc., a biopharmaceutical company developing protein therapeutics for cancer and orphan diseases, today announced the initiation of a phase 2 study of its investigational protein therapeutic, ACE-536, to treat anemia in patients with myelodysplastic syndromes (MDS).

30 Jan 2013

Phenformin decreases size of lung tumors and increases survival in mice

Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases could also work against cancer.

30 Jan 2013

Mice with mitochondrial mutation live longer, have less fat

If findings of a new study in mice are any indication, it might be possible to fine-tune cellular powerhouses called mitochondria, tweaking one aspect to increase insulin sensitivity, reduce body and fat mass, and even extend life. Exploiting this target could one day lead to novel treatments for type 2 diabetes - an endocrine system disease that affects 8 percent of the U.S. population. The research also points to promising new avenues of investigation in the biology of aging.

30 Jan 2013

OncoPep commences PVX-410 Phase 1/2a trial in smoldering multiple myeloma

OncoPep, Inc. today announced that the Company has initiated a Phase 1/2a clinical trial evaluating PVX-410, a multi-peptide therapeutic cancer vaccine, in patients with smoldering multiple myeloma, an asymptomatic precursor of multiple myeloma, which is an incurable cancer of the plasma cells.

30 Jan 2013

U-M to host 11th-annual Depression on College Campuses Conference on Feb. 26-27

Rather than seeking out healthy treatment options, many college students experiencing symptoms of depression or anxiety too often resort to unhealthy coping practices like drug use, drinking, or self-injury.

30 Jan 2013

FDA allows IND application for ImmunoCellular’s ICT-140 to treat ovarian cancer

ImmunoCellular Therapeutics, Ltd. announced that the US Food and Drug Administration (FDA) has allowed the investigational new drug (IND) application for ICT-140, paving the way for conducting a clinical trial.

30 Jan 2013

Human Brain Project to link basic research with disease treatment

King's College London is part of an international consortium of scientists who have today been awarded a grant of over one billion euros, over ten years, to simulate 'everything we know about the human brain' in supercomputers.

30 Jan 2013

New BU institute discovers new ways of making tourist attractions dementia-friendly

New BU institute discovers new ways of making tourist attractions dementia-friendly. Fear of getting lost, fear of not finding the toilets or being misunderstood; there are many reasons why people with dementia and the families who care for them stop going on holiday.

30 Jan 2013

Sanofi introduces LeGoo gel to temporarily stop blood flow during cardiovascular surgery

Sanofi US announced the commercial launch of LeGoo, a biopolymer gel that allows surgeons to temporarily stop blood flow during surgery without the use of clamps, elastic loops or other conventional occlusion devices, which may increase risk of trauma to blood vessels.

30 Jan 2013

Genzyme receives FDA approval for Kynamro to treat homozygous familial hypercholesterolemia

The U.S. Food and Drug Administration today approved Kynamro (mipomersen sodium) injection as an addition to lipid-lowering medications and diet to treat patients with a rare type of high cholesterol called homozygous familial hypercholesterolemia (HoFH).

30 Jan 2013

Controlling blood pressure and cholesterol may reduce risk of heart attack or stroke in diabetics

For people with diabetes, meeting the recommended guidelines for blood pressure and cholesterol is even more important than meeting the guidelines for blood sugar control in reducing the risk of heart attack or stroke, according to a new Kaiser Permanente study published today in the Journal of General Internal Medicine.

29 Jan 2013

One-step, off-the-shelf tool can help evaluate genetic cause of mitochondrial diseases

More powerful gene-sequencing tools have increasingly been uncovering disease secrets in DNA within the cell nucleus. Now a research team is expanding those rapid next-generation sequencing tests to analyze a separate source of DNA—within the genes inside mitochondria, cellular power plants that, when abnormal, contribute to complex, multisystem diseases.

29 Jan 2013

CINJ receives $75,000 grant from Breast Cancer Alliance

For the second consecutive year, The Cancer Institute of New Jersey has been awarded a $75,000 grant from the non-profit entity the Breast Cancer Alliance. The grant, which supports the institute's Breast Surgery Fellowship Program, is for academic year 2013-2014.

29 Jan 2013

ARGO launches ReWalk Rehabilitation 2.0 system

ARGO Medical Technologies has unveiled the newest generation of its ReWalk Rehabilitation exoskeleton that enables individuals with spinal cord injuries the ability to walk again.

29 Jan 2013

U-M researchers develop new method thet could enhance gene sequencing data

When researchers sequence the RNA of cancer cells, they can compare it to normal cells and see where there is more RNA. That can help lead them to the gene or protein that might be triggering the cancer.

29 Jan 2013

German Research Foundation approves funding for Mainz study on cardiovascular disorders

The German Research Foundation has approved funding for the Department of Internal Medicine II of the Mainz University Medical Center to promote the further study of the interrelations between the immune system and cardiovascular system disorders.

29 Jan 2013

Study finds reduction in salt intake among England people after national campaign

The number of people in England adding salt to food at the table fell by more than a quarter in the five years following a national campaign, according to research published in the British Journal of Nutrition.

29 Jan 2013

Consuming carotenoid-rich foods may help prevent or delay onset of amyotrophic lateral sclerosis

New research suggests that increased consumption of foods containing colorful carotenoids, particularly beta-carotene and lutein, may prevent or delay the onset of amyotrophic lateral sclerosis (ALS).

29 Jan 2013

Colorectal cancer screening: an interview with Dr Donato F. Altomare

Colorectal cancer is a malignant neoplasm affecting the large bowel and the rectum mainly after the 5th decade of life and representing the second cause of death for cancer in western countries (the third in women). In about 15-20% of patients there is an inherited predisposition.

29 Jan 2013

Medical Condition News

SOD1 enzyme protects cells by regulating cell energy and metabolism

Acceleron commences ACE-536 phase 2 study in myelodysplastic syndromes

Phenformin decreases size of lung tumors and increases survival in mice

Mice with mitochondrial mutation live longer, have less fat

OncoPep commences PVX-410 Phase 1/2a trial in smoldering multiple myeloma

U-M to host 11th-annual Depression on College Campuses Conference on Feb. 26-27

FDA allows IND application for ImmunoCellular’s ICT-140 to treat ovarian cancer

Human Brain Project to link basic research with disease treatment

New BU institute discovers new ways of making tourist attractions dementia-friendly

Sanofi introduces LeGoo gel to temporarily stop blood flow during cardiovascular surgery

Genzyme receives FDA approval for Kynamro to treat homozygous familial hypercholesterolemia

Controlling blood pressure and cholesterol may reduce risk of heart attack or stroke in diabetics

One-step, off-the-shelf tool can help evaluate genetic cause of mitochondrial diseases

CINJ receives $75,000 grant from Breast Cancer Alliance

ARGO launches ReWalk Rehabilitation 2.0 system

U-M researchers develop new method thet could enhance gene sequencing data

German Research Foundation approves funding for Mainz study on cardiovascular disorders

Study finds reduction in salt intake among England people after national campaign

Consuming carotenoid-rich foods may help prevent or delay onset of amyotrophic lateral sclerosis

Colorectal cancer screening: an interview with Dr Donato F. Altomare

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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