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Intensive lifestyle intervention may increase likelihood of partial remission of type 2 diabetes

Among overweight adults, participation in an intensive lifestyle intervention (that included counseling sessions and targets to reduce caloric intake and increase physical activity) was associated with a greater likelihood of partial remission of type 2 diabetes, however the absolute remission rates were modest, according to a study in the December 19 issue of JAMA.

19 Dec 2012

Targeting km23-1 protein may slow the spread of cancer cells

The spread of cancer cells may be slowed by targeting the protein km23-1, according to researchers at Penn State College of Medicine.

19 Dec 2012

Views on Conn. shootings: Mental illness doesn't generally lead to violence; Need for more treatment options; Helping the survivors

It's possible that preventing people with schizophrenia, bipolar disorder and other serious mental illnesses from getting guns might decrease the risk of mass killings. Even the Supreme Court, which in 2008 strongly affirmed a broad right to bear arms, at the same time endorsed prohibitions on gun ownership "by felons and the mentally ill." But mass killings are very rare events, and because people with mentally illness contribute so little to overall violence, these measures would have little impact on everyday firearm-related killings.

19 Dec 2012

Clopidogrel pretreatment for PCI does not reduce risk of overall mortality

Among patients scheduled for a percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries), pretreatment with the antiplatelet agent clopidogrel was not associated with a lower risk of overall mortality but was associated with a significantly lower risk of major coronary events, according to a review and meta-analysis of previous studies published in the December 19 issue of JAMA.

19 Dec 2012

Budding yeast an acceptable model system to study KP1019 anti-cancer drug

Researchers have found that the budding yeast (Saccharomyces cerevisiae) is an acceptable model system to study KP1019, an anti-cancer drug that uses ruthenium, a rare metal, a new study found. Researchers had previously been interested in studying KP1019 because it is believed to cause cancer cell death and is not known to have negative secondary side effects for healthy tissues.

19 Dec 2012

Metallic probe can detect fibrils from misfolded proteins in real time

Rice University scientists have discovered a new way to look inside living cells and see the insoluble fibrillar deposits associated with Parkinson's disease.

19 Dec 2012

Study: Purines fend off damage during anesthesia

Anesthesia is quite safe these days. But sometimes putting a patient under to fix one problem, such as heart damage, can harm a different organ, such as a kidney.

19 Dec 2012

EMD Serono's L-BLP25 Phase III NSCLC trial does not meet primary endpoint

EMD Serono, a subsidiary of Merck KGaA, Darmstadt, Germany, announced today that the Phase III STARTa trial of its investigational product L-BLP25 (formerly referred to as Stimuvax) in patients with unresectable, locally advanced stage IIIA or IIIB non-small cell lung cancer (NSCLC) did not meet its primary endpoint to demonstrate a statistically significant improvement in overall survival (OS).

19 Dec 2012

British Pharmacological Society celebrates the start of annual meeting

The British Pharmacological Society (BPS) today celebrated the start of its annual meeting, which will cover the latest research in drug discovery over the next three days, including a special focus on discoveries in cancer treatment.

19 Dec 2012

Arthritis, rheumatism and total joint arthroplasty: an interview with Dr Ravi and Dr Hawker

Arthritis translates to “joint inflammation.” The most common form of arthritis is osteoarthritis (OA), which affects 12-15% of North Americans over the age of 60, and will increase in prevalence as our population ages.

19 Dec 2012

Riverside Methodist Hospital treats first PAD patient with Cook Medical's Zilver PTX device

Just weeks after the Food and Drug Administration (FDA) approved Cook Medical's Zilver PTX Drug-Eluting Peripheral Stent, Riverside Methodist Hospital in Columbus, Ohio, has treated the first patient with the device as part of Cook's U.S. commercial launch.

19 Dec 2012

Changes in cholesterol metabolism induced by diet can alter the gut flora

For more than half a century, researchers have known that the bacteria that colonize the gastrointestinal tract of mammals influence their host's cholesterol metabolism. Now, Jens Walter and colleagues of the University of Nebraska show that changes in cholesterol metabolism induced by diet can alter the gut flora.

19 Dec 2012

Food and Function journal publishes Hass Avocado Board study

The Hass Avocado Board (HAB) is supporting research to improve understanding of the unique, positive benefits of consuming fresh avocados to human health and nutrition.

19 Dec 2012

Hypnotherapy helps fight irritable bowel syndrome symptoms

Hypnotherapy helps fight IBS symptoms. These are the findings of a thesis from Sahlgrenska Academy, University of Gothenburg, Sweden which proposes implementing this treatment method into the care of severe sufferers of this common disease.

19 Dec 2012

Myostatin responsible for initiation of muscle loss: Study

A research study from Nanyang Technological University (NTU) has yielded important breakthroughs on how the body loses muscle, paving the way for new treatments for aging, obesity and diabetes.

19 Dec 2012

Making small changes in travel or diet choices may lead to comparable obesity reduction

Those considering how to maintain a healthy weight during holiday festivities, or looking ahead to New Year's resolutions, may want to think twice before reaching for traditional staples like cookies or candy - or the car keys.

19 Dec 2012

Hospital MRIs may effectively predict long-term outcomes for people with mild TBI

Hospital MRIs may be better at predicting long-term outcomes for people with mild traumatic brain injuries than CT scans, the standard technique for evaluating such injuries in the emergency room, according to a clinical trial led by researchers at the University of California, San Francisco (UCSF) and the San Francisco General Hospital and Trauma Center (SFGH).

19 Dec 2012

Medical Condition News

Intensive lifestyle intervention may increase likelihood of partial remission of type 2 diabetes

Targeting km23-1 protein may slow the spread of cancer cells

Views on Conn. shootings: Mental illness doesn't generally lead to violence; Need for more treatment options; Helping the survivors

Clopidogrel pretreatment for PCI does not reduce risk of overall mortality

Budding yeast an acceptable model system to study KP1019 anti-cancer drug

Metallic probe can detect fibrils from misfolded proteins in real time

Study: Purines fend off damage during anesthesia

EMD Serono's L-BLP25 Phase III NSCLC trial does not meet primary endpoint

British Pharmacological Society celebrates the start of annual meeting

Arthritis, rheumatism and total joint arthroplasty: an interview with Dr Ravi and Dr Hawker

Riverside Methodist Hospital treats first PAD patient with Cook Medical's Zilver PTX device

Changes in cholesterol metabolism induced by diet can alter the gut flora

Food and Function journal publishes Hass Avocado Board study

Hypnotherapy helps fight irritable bowel syndrome symptoms

Myostatin responsible for initiation of muscle loss: Study

Making small changes in travel or diet choices may lead to comparable obesity reduction

Hospital MRIs may effectively predict long-term outcomes for people with mild TBI

Link between silent stroke and Parkinson's disease

Study: Half of the benefit of taking sleeping pills comes from the placebo effect

HAL Allergy completes enrollment in SUBLIVAC FIX Phleum pratense Phase II trial

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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